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1.	Allentoft, Morten E., et al. (författare) Population genomics of post-glacial western Eurasia 2024 Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 625:7994, s. 301-311 Tidskriftsartikel (refereegranskat)abstract Western Eurasia witnessed several large-scale human migrations during the Holocene1–5. Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes—mainly from the Mesolithic and Neolithic periods—from across northern and western Eurasia. These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. Our analyses revealed a ‘great divide’ genomic boundary extending from the Black Sea to the Baltic. Mesolithic hunter-gatherers were highly genetically differentiated east and west of this zone, and the effect of the neolithization was equally disparate. Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 bp, consistent with the persistence of localized groups of hunter-gatherers. The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 bp, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. Similar turnovers occurred in western Siberia, where we report new genomic data from a ‘Neolithic steppe’ cline spanning the Siberian forest steppe to Lake Baikal. These prehistoric migrations had profound and lasting effects on the genetic diversity of Eurasian populations.
2.	Gschwendtner, Dda, et al. (författare) The AWAKE Run 2 Programme and Beyond 2022 Ingår i: Symmetry. - : MDPI AG. - 2073-8994. ; 14:8 Tidskriftsartikel (refereegranskat)abstract Plasma wakefield acceleration is a promising technology to reduce the size of particle accelerators. The use of high energy protons to drive wakefields in plasma has been demonstrated during Run 1 of the AWAKE programme at CERN. Protons of energy 400 GeV drove wakefields that accelerated electrons to 2 GeV in under 10 m of plasma. The AWAKE collaboration is now embarking on Run 2 with the main aims to demonstrate stable accelerating gradients of 0.5-1 GV/m, preserve emittance of the electron bunches during acceleration and develop plasma sources scalable to 100s of metres and beyond. By the end of Run 2, the AWAKE scheme should be able to provide electron beams for particle physics experiments and several possible experiments have already been evaluated. This article summarises the programme of AWAKE Run 2 and how it will be achieved as well as the possible application of the AWAKE scheme to novel particle physics experiments.
3.	Kalapos, Peter Pal, et al. (författare) Photoswitching of Local (Anti)Aromaticity in Biphenylene-Based Diarylethene Molecular Switches 2022 Ingår i: Journal of Organic Chemistry. - : American Chemical Society (ACS). - 0022-3263 .- 1520-6904. ; 87:15, s. 9532-9542 Tidskriftsartikel (refereegranskat)abstract Photoinduced tuning of (anti)aromaticity and associated molecular properties is currently in the focus of attention for both tailoring photochemical reactivity and designing new materials. Here, we report on the synthesis and spectroscopic characterization of diarylethene-based molecular switches embedded in a biphenylene structure composed of rings with different levels of local (anti)aromaticity. We show that it is possible to modulate and control the (anti)aromatic character of each ring through reversible photoswitching of the aryl units of the system between open and closed forms. Remarkably, it is shown that the irreversible formation of an annulated bis(dihydro-thiopyran) side-product that hampers the photoswitching can be efficiently suppressed when the aryl core formed by thienyl groups in one switch is replaced by thiazolyl groups in another.

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Typ av publikation: tidskriftsartikel (3)

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Författare/redaktör: Larsson, Lars (1); Zhao, Lei (1); Persson, Per (1); Vincke, Helmut (1); Rosengren, Anders (1); Lynnerup, Niels (1); visa fler...; Sjögren, Karl-Göran, ... (1); Silva, Luís (1); Allentoft, Morten E. (1); Sikora, Martin (1); Fischer, Anders, 195 ... (1); Ingason, Andrés (1); Macleod, Ruairidh (1); Schulz Paulsson, Bet ... (1); Jørkov, Marie Louise ... (1); Stenderup, Jesper (1); Price, T. Douglas (1); Fischer Mortensen, M ... (1); Nielsen, Anne Birgit ... (1); Ulfeldt Hede, Mikkel (1); Sørensen, Lasse (1); Nielsen, Poul Otto (1); Rasmussen, Peter (1); Jensen, Theis Zetner ... (1); Refoyo-Martínez, Alb ... (1); Kristiansen, Kristia ... (1); Barrie, William (1); Pearson, Alice (1); Sousa da Mota, Bárba ... (1); Demeter, Fabrice (1); Henriksen, Rasmus A. (1); Vimala, Tharsika (1); McColl, Hugh (1); Vaughn, Andrew (1); Vinner, Lasse (1); Renaud, Gabriel (1); Stern, Aaron (1); Johannsen, Niels Nør ... (1); Ramsøe, Abigail Dais ... (1); Schork, Andrew Josep ... (1); Ruter, Anthony (1); Gotfredsen, Anne Bir ... (1); Henning Nielsen, Bja ... (1); Brinch Petersen, Eri ... (1); Kannegaard, Esben (1); Hansen, Jesper (1); Buck Pedersen, Krist ... (1); Pedersen, Lisbeth (1); Klassen, Lutz (1); Meldgaard, Morten (1); visa färre...

Lärosäte: Göteborgs universitet (1); Uppsala universitet (1); Linköpings universitet (1); Lunds universitet (1); Linnéuniversitetet (1)

Språk: Engelska (3)

Forskningsämne (UKÄ/SCB): Naturvetenskap (3); Humaniora (1)

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