| 1. |
- Bednar, Peter, et al.
(författare)
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Transformation of Information Systems: Relevance of Expectations
- 2007
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Ingår i: [Host publication title missing]. ; , s. 1-9
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Konferensbidrag (refereegranskat)abstract
- The purpose of the paper is to highlight the influence of expectations of professionals towards a greater role in decision-taking at all levels. This includes an expectation of collaboration in the development of organizational information systems. To this end we drew upon Claudio Ciborra's Mood, represented by his discussion of bricolage, hacking and improvisation and their philosophical foundations in the work of Heidegger. Further, the paper explains how these relate to IS at the level of the organization. Our treatment of Ciborra's vision and concerns contributes towards the realisation of ideals closely relevant to a transformation to professionalisation of citizenship within organizations. Integration of these ideas into information systems development processes would help to develop more desirable systems, in line with changing professional values.
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| 2. |
- Tedeschi, Rosamaria, et al.
(författare)
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Activation of maternal Epstein-Barr virus infection and risk of acute leukemia in the offspring
- 2007
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Ingår i: American Journal of Epidemiology. - : Oxford University Press (OUP). - 0002-9262 .- 1476-6256. ; 165:2, s. 134-137
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Tidskriftsartikel (refereegranskat)abstract
- After identifying an association between maternal Epstein-Barr virus (EBV) reactivation and acute lymphoblastic leukemia (ALL), the authors analyzed a nested case-control study within Finnish and Icelandic maternity cohorts with 7 million years of follow-up to confirm EBV's role in ALL. Offspring of 550,000 mothers were followed up to age 15 years during 1975-1997 by national cancer registries to identify leukemia cases. Mothers of cases and three quarters of matched mothers of controls were identified by national population registers. First-trimester sera from mothers of 304 ALL cases and 39 non-ALL cases and from 943 mothers of controls were analyzed for antibodies to viral capsid antigen, early antigen, and EBV transactivator protein ZEBRA. Relative risk, estimated as odds ratio (95% confidence interval), was adjusted for birth order and sibship size. Combining early antigen and/or ZEBRA immunoglobulin G antibodies with the presence of viral capsid antigen immunoglobulin M antibodies did not increase the estimate for ALL risk for viral capsid antigen immunoglobulin M alone (odds ratio = 1.9, 95% confidence interval: 1.2, 3.0). Both ZEBRA immunoglobulin G antibodies and viral capsid antigen immunoglobulin M antibodies were associated with an increased risk of non-ALL in the offspring (odds ratio = 4.5, 95% confidence interval: 1.3, 16; odds ratio = 5.6, 95% confidence interval: 1.1, 29, respectively), suggesting EBV reactivation in the mothers of non-ALL cases. EBV reactivation may be associated with a proportion of childhood leukemia.
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