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Sökning: WFRF:(Dimmock A. P.)

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1.
  • Akkoyun, S., et al. (författare)
  • AGATA - Advanced GAmma Tracking Array
  • 2012
  • Ingår i: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. - : Elsevier BV. - 0168-9002 .- 0167-5087 .- 1872-9576. ; 668, s. 26-58
  • Tidskriftsartikel (refereegranskat)abstract
    • The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation γ-ray spectrometer. AGATA is based on the technique of γ-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a γ ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of γ-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector- response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer. © 2011 Elsevier B.V. All rights reserved.
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2.
  • Wadsworth, R., et al. (författare)
  • THE NORTHWEST FRONTIER : SPECTROSCOPY OF N similar to Z NUCLEI BELOW MASS 100
  • 2009
  • Ingår i: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 40:3, s. 611-620
  • Tidskriftsartikel (refereegranskat)abstract
    • The spectroscopy and structure of excited states of N similar to Z nuclei in the mass 70-100 region has been investigated using two techniques. In the A similar to 70-80 region fusion evaporation reactions coupled with the recoil-beta-tagging method have been employed at Jyvaskyla to study low-lying states in odd-odd N = Z nuclei. Results from these and other data for known odd-odd nuclei above mass 60 will be discussed. In the heavier mass 90 region a fragmentation experiment has been performed using the RIS-ING/FRS setup at GSI. This experiment was primarily aimed at searching for spin gap isomers in nuclei around A similar to 96. The objectives of the latter experiment will be discussed.
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3.
  • Helbig, K. L., et al. (författare)
  • De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias
  • 2018
  • Ingår i: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 103:5, s. 666-678
  • Tidskriftsartikel (refereegranskat)abstract
    • Developmental and epileptic encephalopathies (DEEs) are severe neurodevelopmental disorders often beginning in infancy or early childhood that are characterized by intractable seizures, abundant epileptiform activity on EEG, and developmental impairment or regression. CACNA1E is highly expressed in the central nervous system and encodes the alpha(1)-subunit of the voltage-gated Ca(V)2.3 channel, which conducts high voltage-activated R-type calcium currents that initiate synaptic transmission. Using next-generation sequencing techniques, we identified de novo CACNA1E variants in 30 individuals with DEE, characterized by refractory infantile-onset seizures, severe hypotonia, and profound developmental impairment, often with congenital contractures, macrocephaly, hyperkinetic movement disorders, and early death. Most of the 14, partially recurring, variants cluster within the cytoplasmic ends of all four S6 segments, which form the presumed Ca(V)2.3 channel activation gate. Functional analysis of several S6 variants revealed consistent gain-of-function effects comprising facilitated voltage-dependent activation and slowed inactivation. Another variant located in the domain II S4-S5 linker results in facilitated activation and increased current density. Five participants achieved seizure freedom on the anti-epileptic drug topiramate, which blocks R-type calcium channels. We establish pathogenic variants in CACNA1E as a cause of DEEs and suggest facilitated R-type calcium currents as a disease mechanism for human epilepsy and developmental disorders.
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4.
  • Allen, R. C., et al. (författare)
  • Energetic ions in the Venusian system : Insights from the first Solar Orbiter flyby
  • 2021
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 656
  • Tidskriftsartikel (refereegranskat)abstract
    • The Solar Orbiter flyby of Venus on 27 December 2020 allowed for an opportunity to measure the suprathermal to energetic ions in the Venusian system over a large range of radial distances to better understand the acceleration processes within the system and provide a characterization of galactic cosmic rays near the planet. Bursty suprathermal ion enhancements (up to similar to 10 keV) were observed as far as similar to 50R(V) downtail. These enhancements are likely related to a combination of acceleration mechanisms in regions of strong turbulence, current sheet crossings, and boundary layer crossings, with a possible instance of ion heating due to ion cyclotron waves within the Venusian tail. Upstream of the planet, suprathermal ions are observed that might be related to pick-up acceleration of photoionized exospheric populations as far as 5R(V) upstream in the solar wind as has been observed before by missions such as Pioneer Venus Orbiter and Venus Express. Near the closest approach of Solar Orbiter, the Galactic cosmic ray (GCR) count rate was observed to decrease by approximately 5 percent, which is consistent with the amount of sky obscured by the planet, suggesting a negligible abundance of GCR albedo particles at over 2 R-V. Along with modulation of the GCR population very close to Venus, the Solar Orbiter observations show that the Venusian system, even far from the planet, can be an effective accelerator of ions up to similar to 30 keV. This paper is part of a series of the first papers from the Solar Orbiter Venus flyby.
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5.
  • Recchia, F, et al. (författare)
  • Position resolution of the prototype AGATA triple-cluster detector from an in-beam experiment
  • 2009
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 604:3, s. 555-562
  • Tidskriftsartikel (refereegranskat)abstract
    • AGATA belongs to a new generation of gamma-ray detector arrays for nuclear spectroscopy at present in its final stage of development. The detectors of these new arrays will be based on 36-fold electronically segmented coaxial germanium diodes operated in position sensitive mode. An in-beam test of the AGATA prototype triple cluster detector was carried out with the purpose of demonstrating the feasibility of such detectors and in order to measure the most sensitive parameters for their overall performance. An inverse kinematics reaction was performed, using a Ti-48 beam at an energy of 100MeV, impinging on a deuterated titanium tat-get. The results from the analysis of the experimental data, compared with the predictions of Monte Carlo Simulations, give an estimation of the position sensitivity of these detectors of about 5 mm FWHM, consistent with the specifications required. (C) 2009 Elsevier B.V. All rights reserved.
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6.
  • Singh, B. S. Nara, et al. (författare)
  • Coulomb shifts and shape changes in the mass 70 region
  • 2007
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 75:6
  • Tidskriftsartikel (refereegranskat)abstract
    • The technique of recoil beta tagging has been developed which allows prompt gamma decays in nuclei from excited states to be correlated with electrons from their subsequent short-lived beta decay. This technique is ideal for studying nuclei very far from stability and improves in sensitivity for very short-lived decays and for high decay Q-values. The method has allowed excited states in Y-78 to be observed for the first time, as well as an extension in the knowledge of T=1 states in Rb-74. From this new information it has been possible to compare Coulomb energy differences (CED) between T=1 states in Br-70/Se-70, Rb-74/Kr-74, and Y-78/Sr-78. The A=70 CED exhibit an anomalous behavior which is inconsistent with all other known CED. This behavior may be accounted for qualitatively in terms of small variations in the Coulomb energy arising from shape changes.
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7.
  • Hadid, L. Z., et al. (författare)
  • BepiColombo's Cruise Phase : Unique Opportunity for Synergistic Observations
  • 2021
  • Ingår i: Frontiers in Astronomy and Space Sciences. - : Frontiers Media S.A.. - 2296-987X. ; 8
  • Tidskriftsartikel (refereegranskat)abstract
    • The investigation of multi-spacecraft coordinated observations during the cruise phase of BepiColombo (ESA/JAXA) are reported, with a particular emphasis on the recently launched missions, Solar Orbiter (ESA/NASA) and Parker Solar Probe (NASA). Despite some payload constraints, many instruments onboard BepiColombo are operating during its cruise phase simultaneously covering a wide range of heliocentric distances (0.28 AU-0.5 AU). Hence, the various spacecraft configurations and the combined in-situ and remote sensing measurements from the different spacecraft, offer unique opportunities for BepiColombo to be part of these unprecedented multipoint synergistic observations and for potential scientific studies in the inner heliosphere, even before its orbit insertion around Mercury in December 2025. The main goal of this report is to present the coordinated observation opportunities during the cruise phase of BepiColombo (excluding the planetary flybys). We summarize the identified science topics, the operational instruments, the method we have used to identify the windows of opportunity and discuss the planning of joint observations in the future.
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8.
  • Singh, B. S. Nara, et al. (författare)
  • Recoil Beta Tagging : Application to the study of odd-odd near proton drip line nuclei, Rb-74 and Y-78
  • 2007
  • Ingår i: The European Physical Journal Special Topics. - : Springer Science and Business Media LLC. - 1951-6355 .- 1951-6401. ; 150, s. 147-148
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a study of low-spin states in Rb-74 and Y-78 using the new technique of Recoil Beta Tagging. This yielded new information on Rb-74 and has provided the first evidence for non-isomeric T = 1 states in Y-78.
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9.
  • Branduardi-Raymont, G., et al. (författare)
  • Exploring solar-terrestrial interactions via multiple imaging observers
  • 2022
  • Ingår i: Experimental astronomy. - : Springer Nature. - 0922-6435 .- 1572-9508. ; 54:2-3, s. 361-390
  • Tidskriftsartikel (refereegranskat)abstract
    • How does solar wind energy flow through the Earth's magnetosphere, how is it converted and distributed? is the question we want to address. We need to understand how geomagnetic storms and substorms start and grow, not just as a matter of scientific curiosity, but to address a clear and pressing practical problem: space weather, which can influence the performance and reliability of our technological systems, in space and on the ground, and can endanger human life and health. Much knowledge has already been acquired over the past decades, particularly by making use of multiple spacecraft measuring conditions in situ, but the infant stage of space weather forecasting demonstrates that we still have a vast amount of learning to do. A novel global approach is now being taken by a number of space imaging missions which are under development and the first tantalising results of their exploration will be available in the next decade. In this White Paper, submitted to ESA in response to the Voyage 2050 Call, we propose the next step in the quest for a complete understanding of how the Sun controls the Earth's plasma environment: a tomographic imaging approach comprising two spacecraft in highly inclined polar orbits, enabling global imaging of magnetopause and cusps in soft X-rays, of auroral regions in FUV, of plasmasphere and ring current in EUV and ENA (Energetic Neutral Atoms), alongside in situ measurements. Such a mission, encompassing the variety of physical processes determining the conditions of geospace, will be crucial on the way to achieving scientific closure on the question of solar-terrestrial interactions.
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10.
  • Carter, J. A., et al. (författare)
  • Ground-based and additional science support for SMILE
  • 2024
  • Ingår i: Earth and Planetary Physics. - : Science Press. - 2096-3955. ; 8:1, s. 275-298
  • Tidskriftsartikel (refereegranskat)abstract
    • The joint European Space Agency and Chinese Academy of Sciences Solar wind Magnetosphere Ionosphere Link Explorer (SMILE) mission will explore global dynamics of the magnetosphere under varying solar wind and interplanetary magnetic field conditions, and simultaneously monitor the auroral response of the Northern Hemisphere ionosphere. Combining these large-scale responses with medium and fine-scale measurements at a variety of cadences by additional ground-based and space-based instruments will enable a much greater scientific impact beyond the original goals of the SMILE mission. Here, we describe current community efforts to prepare for SMILE, and the benefits and context various experiments that have explicitly expressed support for SMILE can offer. A dedicated group of international scientists representing many different experiment types and geographical locations, the Ground-based and Additional Science Working Group, is facilitating these efforts. Preparations include constructing an online SMILE Data Fusion Facility, the discussion of particular or special modes for experiments such as coherent and incoherent scatter radar, and the consideration of particular observing strategies and spacecraft conjunctions. We anticipate growing interest and community engagement with the SMILE mission, and we welcome novel ideas and insights from the solar-terrestrial community.
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