| 1. |
- Aghoutane, Youssra, et al.
(författare)
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Development of a molecularly imprinted polymer electrochemical sensor and its application for sensitive detection and determination of malathion in olive fruits and oils
- 2020
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Ingår i: Bioelectrochemistry. - : Elsevier. - 1567-5394 .- 1878-562X. ; 132
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Tidskriftsartikel (refereegranskat)abstract
- Malathion (MAL) is an organophosphorus (OP) insecticide. It is a cholinesterase inhibitor, 15 which can pose serious health and environmental problems. In this study, a sensitive and 16 selective molecular imprinted polymer (MIP) based on screen-printed gold electrodes (Au-17 SPE) for MAL detection in olive oils and fruits, was devised. The MIP sensor was prepared 18 using acrylamide as the functional monomer and MAL as the template. Subsequently, the 19 morphology of the electrode surface was studied by scanning electron microscopy (SEM) and 20 atomic force microscopy (AFM). The electrochemical characterization of the developed MIP 21 sensor was performed by cyclic voltammetry (CV), differential pulse voltammetry (DPV), 22 and electrochemical impedance spectroscopy (EIS) techniques. The operational repeatability 23 and stability of the sensor were studied. It was found to have a dynamic concentration range 24 of (0.1 pg mL-1-1000 pg mL-1) and a low limit of detection (LOD) of 0.06 pg mL-1. 25 Furthermore, the sensor was employed to determine MAL content in olive oil with a recovery 26 rate of 87.9% and a relative standard deviation of 8%. It was successfully applied for MAL 27 determination in real samples and promise to open new opportunities for the detection of OP 28 pesticides residues in various food products, as well as in environmental applications.
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| 2. |
- Diouf, Alassane, et al.
(författare)
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An electrochemical sensor based on chitosan capped with gold nanoparticles combined with a voltammetric electronic tongue for quantitative aspirin detection in human physiological fluids and tablets
- 2020
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Ingår i: Materials science & engineering. C, biomimetic materials, sensors and systems. - : ELSEVIER. - 0928-4931 .- 1873-0191. ; 110
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Tidskriftsartikel (refereegranskat)abstract
- Inflammatory diseases increase has recently sparked the research interest for drugs diagnostic tools development. At therapeutic doses, acetylsalicylic acid (ASA or aspirin) is widely used for these diseases' treatment. ASA overdoses can however give rise to adverse side effects including ulcers, gastric damage. Hence, development of simple, portable and sensitive methods for ASA detection is desirable. This paper reports aspirin analysis in urine, saliva and pharmaceutical tablet using an electrochemical sensor and a voltammetric electronic tongue (VE-Tongue). The electrochemical sensor was fabricated by self-assembling chitosan capped with gold nanoparticles (Cs + AuNPs) on a screen-printed carbon electrode (SPCE). It exhibits a logarithmic-linear relationship between its response and the ASA concentration in the range between 1 pg/mL and 1 mu g/mL. A low detection limit (0.03 pg/mL), good selectivity against phenol and benzoic acid interference, and successful practical application were demonstrated. Qualitative analysis was performed using the VE-Tongue based unmodified metal electrodes combined with two chemometric approaches to classify urine samples spiked with different aspirin concentrations. Partial least squares (PLS) method provided prediction models obtained from the data of both devices with a regression correlation coefficient R-2 = 0.99. Correspondingly, the SPCE/(Cs + AuNPs) electrochemical sensor and VE-Tongue could be viable tools for biological analysis of drugs.
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