| 1. |
- Romanak, Katherine, et al.
(författare)
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Attitudes on Carbon Capture and Storage (CCS) as a Mitigation Technology within the UNFCCC
- 2021
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Ingår i: Energies. - : MDPI. - 1996-1073. ; 14:3
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Tidskriftsartikel (refereegranskat)abstract
- Carbon Capture and Storage (CCS) is a technology for mitigating emissions from large point‐source industries. In addition to the primary role of reducing carbon dioxide (CO2) in the atmosphere, CCS forms the basis for two large‐scale negative emissions technologies by coupling geologic CO2 storage with bioenergy (BECCS) and direct air carbon capture (DACCS). Despite its inclusion within the United Nations Framework Convention on Climate Change (UNFCCC), CCS has been largely unsupported by UNFCCC delegates because of its association with fossil fuels. We evaluate data from surveys given since 2015 to UNFCCC delegates at the Conference of the Parties (COPs) to ascertain how attitudes about bioenergy, BECCS, and CCS may be changing within the UNFCCC. The results show a positive change in attitudes over time for both fossil CCS and BECCS. Using a unique data analysis method, we ascertain that, in some instances, popularity of BECCS increased due to an increased acceptance of CCS despite lower opinions of bioenergy. Business and research NGOs have the most positive views of CCS, and environmental NGOs the most negative views. Delegates that attend CCS side‐events have more positive attitudes towards CCS than nonattendees. Developing countries have a larger need and a greater appetite for information on BECCS than developed countries, but a need for information exists in both.
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| 2. |
- Sawcer, Stephen, et al.
(författare)
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- 2011
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 476:7359, s. 214-219
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Tidskriftsartikel (refereegranskat)abstract
- Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis.
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