| 1. |
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| 2. |
- Grigorenko, L, et al.
(författare)
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Scientific program of DERICA-prospective accelerator and storage ring facility for radioactive ion beam research
- 2019
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Ingår i: Physics-Uspekhi. - 1468-4780 .- 1063-7869. ; 62:7, s. 675-690
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Tidskriftsartikel (refereegranskat)abstract
- Studies of radioactive ions (RIs) are the most thriving field of low-energy nuclear physics. In this paper, the concept and the scientific agenda of the prospective accelerator and storage ring facility for RI beam (RIB) research are proposed for a large-scale international project based at the Flerov Laboratory of Nuclear Reactions of the Joint Institute for Nuclear Research. The motivation for the new facility is discussed and its characteristics are briefly presented and shown to be comparable to those of advanced world centers, the so-called "RIB factories". In the project, the emphasis is made on studies with short-lived RIBs in storage rings. A unique feature of the project is the possibility of studying electron-RI interactions in a collider experiment to determine the fundamental properties of nuclear matter, in particular, electromagnetic form factors of exotic nuclei.
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| 3. |
- Damgaard, P. D., et al.
(författare)
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137 ancient human genomes from across the Eurasian steppes
- 2018
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 557:7705, s. 369-374
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Tidskriftsartikel (refereegranskat)abstract
- For thousands of years the Eurasian steppes have been a centre of human migrations and cultural change. Here we sequence the genomes of 137 ancient humans (about 1x average coverage), covering a period of 4,000 years, to understand the population history of the Eurasian steppes after the Bronze Age migrations. We find that the genetics of the Scythian groups that dominated the Eurasian steppes throughout the Iron Age were highly structured, with diverse origins comprising Late Bronze Age herders, European farmers and southern Siberian hunter-gatherers. Later, Scythians admixed with the eastern steppe nomads who formed the Xiongnu confederations, and moved westward in about the second or third century bc, forming the Hun traditions in the fourthfifth century ad, and carrying with them plague that was basal to the Justinian plague. These nomads were further admixed with East Asian groups during several short-term khanates in the Medieval period. These historical events transformed the Eurasian steppes from being inhabited by Indo-European speakers of largely West Eurasian ancestry to the mostly Turkic-speaking groups of the present day, who are primarily of East Asian ancestry.
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| 4. |
- Zuev, D. A., et al.
(författare)
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Multifunctional Sensing with Hybrid Nanophotonic Structures
- 2017
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Ingår i: Progress in Electromagnetics Research Symposium. - 1559-9450 .- 1931-7360. ; , s. 1491-1493
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Konferensbidrag (refereegranskat)abstract
- The development of multifunctional systems for investigation of different parameters involved in chemical reactions is a vital problem in case of low concentrations of tested matter. Here, we investigate hybrid plasmonic-dielectric system and demonstrate possibility of such application for multifunctional sensing.
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| 5. |
- Haraldson, Klas, et al.
(författare)
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LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication
- 2012
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Ingår i: Biochimie. - : Elsevier. - 0300-9084 .- 1638-6183. ; 94:5, s. 1151-1157
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Tidskriftsartikel (refereegranskat)abstract
- Chromosome 3 specific NotI microarrays containing 180 NotI linking clones associated with 188 genes were hybridized to NotI representation probes prepared using matched tumor/normal samples from major epithelial cancers: breast (47 pairs), lung (40 pairs) cervical (43 pairs), kidney (34 pairs of clear cell renal cell carcinoma), colon (24 pairs), ovarian (25 pairs) and prostate (18 pairs). In all tested primary tumors (compared to normal controls) methylation and/or deletions was found. For the first time we showed that the gene LRRC3B was frequently methylated and/or deleted in breast carcinoma - 32% of samples, cervical - 35%, lung - 40%, renal - 35%, ovarian - 28%, colon - 33% and prostate cancer - 44%. To check these results bisulfite sequencing using cloned PCR products with representative two breast, one cervical, two renal, two ovarian and two colon cancer samples was performed. In all cases methylation was confirmed. Expression analysis using RT-qPCR showed that LRRC3B is strongly down-regulated at the latest stages of RCC and ovarian cancers. In addition we showed that LRRC3B exhibit strong cell growth inhibiting activity (more than 95%) in colony formation experiments in vitro in KRC/Y renal cell carcinoma line. All these data suggest that LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.
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| 6. |
- Blanter, M. S., et al.
(författare)
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Ab initio Based O-O Investigation and the Snoek Relaxation in Nb-O
- 2012
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Ingår i: Diffusion and Defect Data Pt.B. - : Trans Tech Publications Inc.. - 9783037853382 ; , s. 63-68
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Konferensbidrag (refereegranskat)abstract
- It is common knowledge that interstitial-interstitial interaction influence on the Snoek relaxation. We used a computer simulation of this effect in the Nb-O alloy to test the adequacy of various models of the O-O interaction and clarify the mechanism of this effect The energy calculations in the first twelve coordination shells have been performed by the projector augmentedwave (PAW) method as implemented in the Vienna ab initio simulation package (VASP). The energies have been calculated in different ways which vary in the method of determination the energy of non-interacting O-O pairs. The energies calculated on the various variants are similar but in one case there is O-O repulsion in all first twelve coordination shells, whereas in another one can see attraction in four of twelve shells. Internal friction Q -1 was calculated as a sum of the contributions from individual interstitial atoms in different environments, each of which being assumed to be the Debye function. It is assumed that long-range interaction of oxygen atoms affects the distribution of these atoms and the energy of each interstitial atom in the octahedral interstices before a jump and after a jump. The Monte Carlo method is used for simulating short-range order of interstitial atoms and for calculating values of energy changes. Comparison of the calculated temperature and concentration dependence of the Snoek peak with the published data showed that the PAW supercell calculation of the O-O interactions in Nb describes the behavior of the interstitial solid solution adequately. It proves also that the impact of interstitial atom concentration on the Snoek relaxation is connected to the mutual attraction of these atoms.
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| 7. |
- Blanter, M. S., et al.
(författare)
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Interaction of interstitial atoms and configurational contribution to their thermodynamic activity in V, Nb, and Ta
- 2017
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Ingår i: Physics of metals and metallography. - : Maik Nauka/Interperiodica. - 0031-918X .- 1555-6190. ; 118:2, s. 105-112
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Tidskriftsartikel (refereegranskat)abstract
- The pairwise interaction energies of O–O and N–N in bcc metals of group VB, which were calculated earlier using first-principles methods, have been employed to analyze the effect of the interatomic interactions on the configurational contribution to the thermodynamic activity. The strong effect of interstitial- interstitial interaction has been shown. The configurational contribution grows in the row (Nb–N) → (V–N) → (Ta–N) → (Nb–O) → (V–O) → (Ta–O), which is caused by a weakening of the mutual attraction of interstitial atoms in these solid solutions. The strong repulsion that characterizes the majority of coordination shells only weakly affects the thermodynamic activity. The character of the temperature dependence of the configurational contribution is defined by the strength of the mutual attraction of the interstitial atoms, i.e., upon strong attraction, the contribution increases with increasing temperature (Nb–N, V–N, Ta–N, and Nb–O) and, upon weak attraction, it decreases (V–O and Ta–O).
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| 8. |
- Blanter, M. S., et al.
(författare)
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Interstitial-interstitial interactions in bcc VB group metals : Ab initio calculations
- 2013
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Ingår i: Journal of Physics and Chemistry of Solids. - : Elsevier BV. - 0022-3697 .- 1879-2553. ; 74:5, s. 716-722
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Tidskriftsartikel (refereegranskat)abstract
- Chemical and strain-induced interactions of oxygen and nitrogen interstitials in bcc V and Ta have been obtained for the first 12 coordination shells in the supercell first-principles calculations by the Viena ab initio simulation package (VASP). It is shown that the chemical interactions are dominating at the first several coordination shells while the strain-induced interactions become important at more distant coordination shells. The latter are in reasonable agreement with the earlier results of a microscopic phenomenological Krivoglaz-Kanzaki-Khachaturyan model (KKKM). The obtained interstitial-interstitial interactions have been used in calculations of the concentration dependence of the oxygen Snoek peak, which is in good agreement with the existing experimental data.
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| 9. |
- Blanter, M. S., et al.
(författare)
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Ordering in V-O and V-N solid solutions : Computer simulation
- 2014
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Ingår i: Bulletin of the Russian Academy of Sciences: Physics. - 1062-8738. ; 78:10, s. 1030-1034
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Tidskriftsartikel (refereegranskat)abstract
- The atomic structures of interstitial solid solutions O and N in V at relatively low concentrations O(N)/V = 1/16 or 1/8 are calculated using the Monte Carlo method. A combined model of long-range interaction between interstitial atoms is employed. The first 12 shells contain ab initio energies and the energies in shells 13–18 are calculated on the basis of a phenomenological model of deformation interaction. The ordered solid solutions are long-period structures with body-centered tetragonal crystal lattices and tetragonality c/a < 1.
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| 10. |
- Blanter, M. S., et al.
(författare)
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Strain-induced interaction of interstitials in IVA group hcp metals
- 2010
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Ingår i: Journal of Physics and Chemistry of Solids. - : Elsevier BV. - 0022-3697 .- 1879-2553. ; 71:10, s. 1416-1420
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Tidskriftsartikel (refereegranskat)abstract
- Strain-induced (elastic) interactions of oxygen, nitrogen and carbon atoms in IVA group metals, alpha-Ti, Zr, and -Hf, are calculated in the framework of the microscopic Krivoglaz-Kanzaki-Khachaturyan theory. The experimental elastic constants, lattice spacing of the host metal, and concentration expansion coefficients are used as the input numerical parameters. The resulting interactions are stronger in a-Ti than in alpha-Zr and alpha-Hf. A comparative analysis of interactions in the hcp IVA group metals with those in bcc and fcc solid solutions reveals the crystal structure effect. In general, the strain-induced interactions of O, N, and C in hcp IVA group metals are weaker than in bcc solid solutions and are stronger than in fcc solid solutions.
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