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| 2. |
- Gnauck, Maja, et al.
(författare)
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Knowledge and competence in temporomandibular disorders among Swedish general dental practitioners and dental hygienists
- 2017
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Ingår i: Acta Odontologica Scandinavica. - : Informa Healthcare. - 0001-6357 .- 1502-3850. ; 75:6, s. 429-436
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to investigate knowledge and competence in temporomandibular disorders (TMD) among dentists and dental hygienists working in the public dental service (PDS) in Sweden. Materials and methods: The study population comprised all general dentists (n = 110) and dental hygienists (n = 80) working in the PDS in two Swedish counties: Kronoberg (K) and Blekinge (B). The participants filled out a questionnaire comprised of 15 questions. Results: The results of these questions are presented. The overall response rate for the general dentists was 87%, while the rate for the dental hygienists was 71%. Statistically significant differences between the general dentists in the two counties were found regarding the following: education in the field of TMD over the last 5 years (K: 37%, B: 73%), evaluation of occlusion when examining patients with suspected TMD ('always': K: 61%, B: 82%), and a desire for consultation of the OFP (orofacial pain)/TMD specialist by telephone (K: 71%, B: 44%). Regarding the dental hygienists, there was a statistically significant difference concerning the use of the treatment modality 'reassurance' (K: 41%, B: 7%). Conclusions: The majority of the dental care providers in both counties - irrespective of professional category - had a positive attitude towards patients with TMD. Knowledge and competence in the field are sparse and require postgraduate education. There is a great need of an OFP/TMD specialist for more complicated patients and a need to implement updated knowledge and competence in the PDS in these two counties.
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- Arzola, Luis H., et al.
(författare)
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Viabahn-assisted sutureless anastomosis (VASA) repair of a complex internal carotid artery aneurysm
- 2023
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Ingår i: Journal of Vascular Surgery Cases and Innovative Techniques. - : Elsevier. - 2468-4287. ; 9:2
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Tidskriftsartikel (refereegranskat)abstract
- Extracranial carotid artery aneurysms (CAAs) are extremely rare and often require surgical intervention to avoid complications such as local compression symptoms and thrombo-embolization. We present the case of a 63-year-old man with a history of hypertension, meningioma, and an incidental finding of a right saccular internal carotid artery aneurysm at the base of the skull. He underwent open surgical repair; nonetheless, end-to-end anastomosis was not feasible. As bailout, the internal carotid artery was successfully reconstructed with a novel Viabahn-assisted sutureless anastomosis technique (GORE, Viabahn). Postoperative clinical assessment revealed no complications, postoperative computed tomography angiography revealed a patent reconstruction, and the patient was discharged home uneventfully with 1-year clinical and computed tomography angiography follow-up without remarks. Hybrid procedure is a viable option for technically challenging carotid anastomoses near the skull base.
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| 4. |
- Borota, Ljubisa, et al.
(författare)
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Combined percutaneous and transarterial devascularisation of juvenile nasopharyngeal angiofibroma with protection of internal carotid artery : A modification of the technique
- 2015
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Ingår i: Interventional Neuroradiology. - : SAGE Publications. - 1591-0199 .- 2385-2011. ; 21:3, s. 390-396
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Tidskriftsartikel (refereegranskat)abstract
- Juvenile nasal angiofibroma (JNA) is a hypervascularised, benign, but locally aggressive tumour that grows in the posterior, upper part of the nasal cavity and invades surrounding anatomical structures. The treatment of choice is surgical removal, but complete resection of the tumour can be hampered because of profuse perioperative bleeding. Preoperative embolisation of the tumour has been proposed as an effective method for prevention of perioperative bleeding, thereby shortening of the time of the operation. In this report of five cases, we describe successful preoperative devascularisation of the tumour by applying a modified method of direct intratumoural injection of the liquid embolic agent Onyx combined with protection of the internal carotid artery. The control of bleeding during the embolisation and occlusion of the maxillary or sphenopalatine artery was achieved by using a bi-luminal balloon catheter. Such use of the dual-lumen catheter in treatment of JNA has not been reported so far in the medical literature.
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| 7. |
- Cheng, Junping, et al.
(författare)
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Radioimmunotherapy with astatine-211 using chimeric monoclonal antibody U36 in head and neck squamous cell carcinoma
- 2007
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Ingår i: The Laryngoscope. - 0023-852X .- 1531-4995. ; 117:6, s. 1013-1018
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: In advanced head and neck squamous cell carcinoma (HNSCC), there is a need for an adjuvant treatment. We aim to evaluate the biodistribution and therapeutic effect of radioimmunotherapy using the alpha emitting, astatine-211-labeled, chimeric monoclonal antibody U36 (U36) on the HNSCC cell line UT-SCC7 in vivo. STUDY DESIGN: Xenograft tumors were inoculated subcutaneously in nude mice. Astatine-211-labeled U36 was injected intravenously with or without blocking of target with nonlabeled U36. METHODS: In the biodistribution experiments, radioactivity was measured in tumors and various organs at set time points. In the therapeutic experiments, two groups (with or without blocking) received therapy, and the tumor growth was compared with that of controls. In addition, one group received nonlabeled U36 only. RESULTS: The biodistribution experiments demonstrated that astatine-211-labeled U36 could target UT-SCC7 xenografts in nude mice. With time, uptake increased in tumors and decreased in normal organs. Nonlabeled U36 did not influence tumor growth. In the two therapy groups, 18 of 20 tumors responded to therapy by decreasing or stabilizing their volumes. Significant difference was seen between the treated groups and the controls (P < .05). CONCLUSION: The study illustrates the specific binding of astatine-211-labeled U36 to HNSCC and suggests radioimmunotherapy with the alpha emitting radionuclide to be a useful treatment modality.
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| 8. |
- Cheng, Junping, et al.
(författare)
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The use of closo-dodecaborate-containing linker improves targeting of HNSCC xenografts with radioiodinated chimeric monoclonal antibody U36
- 2010
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Ingår i: Molecular Medicine Reports. - : Spandidos Publications. - 1791-2997. ; 3:1, s. 155-160
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Tidskriftsartikel (refereegranskat)abstract
- Radionuclide imaging of head and neck squamous cell carcinoma (HNSCC) using monoclonal antibodies (MAbs) has the potential to contribute to improved diagnosis and staging, thereby making more effective treatment possible. Chimeric monoclonal antibody U36 (cMAb U36), specific to CD44v6 antigen. is a candidate for the targeting of HNSCC. The aim of this study was to compare the influence of indirect iodination via closo-dodecaborate-based linker (DABI) with the influence of direct radioiodination on the biodistribution of the chimeric anti-CD44v6 antibody U36. The study was performed using nude mice bearing UT-SCC7 HNSCC xenografts using the paired-label method. The biodistribution of cMAb U36 labelled directly with I-131 and using DABI with I-125 was compared in the same animals. The influence of DABI on the tumour-to-organ ratio was evaluated. For both conjugates, radioactivity uptake in blood and organs decreased with time, except in tumours and the thyroid. DABI-labelled cMAb U36 was characterised by fast blood clearance and an elevated uptake in the liver and spleen. The use of DABI enabled a 1.5 to 2-fold improvement in the tumour-to-blood and tumour-to-organ ratios in comparison with direct radioiodination, with the exception of the liver and spleen. These results indicate that DABI is a promising linker for the coupling of radioiodine to HNSCC-targeting antibodies.
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| 9. |
- Dahlgren, Anita, et al.
(författare)
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Idrott och hälsa i skolan, och föreningsidrott på fritiden – eller?
- 2007
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Ingår i: Resultatdialog 2007. - : Vetenskapsrådet. - 9789173071154 ; , s. 29-35
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Skolans verksamhet är ständigt i fokus och föremål för mångas tänkande och tyckande. Alla är eller har på något sätt varit berörda av den. Skolan är en komplex verksamhet, som skall uppfylla både samhällets och individens behov och krav. Verksamheten studeras och utvärderas för att göra den så givande och bra som möjligt för varje enskild individ. I ett skolämne som Idrott och hälsa finns även en tydlig relation till föreningsliv (idrott) och en betydelse för samhället (hälsa). På senare tid har ett ökat antal studier fokuserat på ämnet och dess förutsättningar och effekter. Många av dessa studier har koncentrerat sig på lärares/elevers uppfattning av verksamheten och är inte i första hand studier av de processer som sker i själva verksamheten. Det finns således ett behov av kunskap om de organiserade lärandesituationerna i skolan. Syftet med projektet är att, med den organiserade lärandesituationen i centrum, dvs., lektionen i Idrott och hälsa, studera och beskriva olika faktorer som påverkar skeendet, och en central del är att studera det faktiska skeendet. Lärarnas och elevernas förståelse för och erfarenhet av idrott och ämnet Idrott och hälsa utgör en andra del av studien. En tredje del syftar till att belysa de sociala sammanhang elever och lärare befinner sig i med hänsyn bland annat till kön och social bakgrund.
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| 10. |
- Ekberg, Lars, et al.
(författare)
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Ventilation i Sverige : En kunskapssammanställning
- 2022
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Boverket ser ett behov av en kunskapssammanställning kring nuläget för ventilation för att ha en så bred och korrekt förståelse som möjligt för vem branschen är, vilka regler som tillämpas, var det finns kunskapscentra och vilka utvecklingsbehov som behöver stödjas.Rapporten tar uppVentilation som en del av byggnaden; Ventilation i bostäder; Ventilation i lokaler; Ventilation och inneklimatkrav (regelverk) samt kontroller; Mäta och verifiera inneklimat och ventilation; Energikrav och rekommendationer för ventilation; Brandskydd och ventilation; Ventilations påverkan på smittspridning; Vägledningar för ventilation och inomhusklimat; Branschens aktörer i SVerige; En fördjupande enkät; Behov av fortsatt kartläggning
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