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- Adeloye, Davies, et al.
(författare)
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Research priorities to address the global burden of chronic obstructive pulmonary disease (COPD) in the next decade
- 2021
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Ingår i: Journal of Global Health. - : International Global Health Society. - 2047-2986 .- 2047-2978. ; 11, s. 15003-15003
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Tidskriftsartikel (refereegranskat)abstract
- Background: The global prevalence of chronic obstructive pulmonary disease (COPD) has increased markedly in recent decades. Given the scarcity of resources available to address global health challenges and respiratory medicine being relatively under-invested in, it is important to define research priorities for COPD globally. In this paper, we aim to identify a ranked set of COPD research priorities that need to be addressed in the next 10 years to substantially reduce the global impact of COPD. Methods: We adapted the Child Health and Nutrition Research Initiative (CHNRI) methodology to identify global COPD research priorities. Results: 62 experts contributed 230 research ideas, which were scored by 34 researchers according to six pre-defined criteria: answerability, effectiveness, feasibility, deliverability, burden reduction, and equity. The top-ranked research priority was the need for new effective strategies to support smoking cessation. Of the top 20 overall research priorities, six were focused on feasible and cost-effective pulmonary rehabilitation delivery and access, particularly in primary/community care and low-resource settings. Three of the top 10 overall priorities called for research on improved screening and accurate diagnostic methods for COPD in low-resource primary care settings. Further ideas that drew support involved a better understanding of risk factors for COPD, development of effective training programmes for health workers and physicians in low resource settings, and evaluation of novel interventions to encourage physical activity. Conclusions: The experts agreed that the most pressing feasible research questions to address in the next decade for COPD reduction were on prevention, diagnosis and rehabilitation of COPD, especially in low resource settings. The largest gains should be expected in low- and middle-income countries (LMIC) settings, as the large majority of COPD deaths occur in those settings. Research priorities identified by this systematic international process should inform and motivate policymakers, funders, and researchers to support and conduct research to reduce the global burden of COPD.
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| 3. |
- Hedeving, Anna, et al.
(författare)
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Thin loess in Southwestern Sweden
- 2024
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Ingår i: GFF. - 1103-5897 .- 2000-0863.
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Tidskriftsartikel (refereegranskat)abstract
- A thin (20–80 cm), patchy layer of silt-rich sediment occurs at the surface throughout Svartedalen, a nature reserve 30 km north of Gothenburg, Sweden. This surface silt mantles a bedrock-dominated, fracture-valley landscape. Using data from grain-size analysis, OSL dating and detrital-zircon U-Pb dating, we argue that the silt is loess sourced from glacial sediment that was eroded from local bedrock. The sediment has a grain-size distribution typical of wind-blown silt and is especially similar to thin deposits of loess overlying coarser material. OSL ages on five samples range from 1 to 8 ka, although analysis of equivalent dose distributions of one may suggest an age as old as 11 ka. The dates may represent true depositional ages and represent several Holocene eolian events. However, we consider as more likely that the loess was deposited during deglaciation, and quartz-grain signals have been partially reset during bioturbation. U-Pb ages on 273 zircon grains from the loess show prominent peaks at 1.6 and 1.8 Ga, as well as smaller numbers of grains from 1.0 to 1.6 Ga. These ages match dates from the Idefjord Terrane which comprises the bedrock of the study area. We argue that during ice-margin retreat, debris in the glacier was dominated by locally derived debris. This glacial sediment was left in thin patches uplands and particularly in large ice-marginal deltas. These deposits served as the proximal source for the loess. The presence of thin loess in Svartedalen suggests loess to be common in soils of southwest Sweden.
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| 4. |
- Hedeving, Anna, et al.
(författare)
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Thin loess in Southwestern Sweden
- 2024
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Ingår i: GFF. - 1103-5897 .- 2000-0863.
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Tidskriftsartikel (refereegranskat)abstract
- A thin (20-80 cm), patchy layer of silt-rich sediment occurs at the surface throughout Svartedalen, a nature reserve 30 km north of Gothenburg, Sweden. This surface silt mantles a bedrock-dominated, fracture-valley landscape. Using data from grain-size analysis, OSL dating and detrital-zircon U-Pb dating, we argue that the silt is loess sourced from glacial sediment that was eroded from local bedrock. The sediment has a grain-size distribution typical of wind-blown silt and is especially similar to thin deposits of loess overlying coarser material. OSL ages on five samples range from 1 to 8 ka, although analysis of equivalent dose distributions of one may suggest an age as old as 11 ka. The dates may represent true depositional ages and represent several Holocene eolian events. However, we consider as more likely that the loess was deposited during deglaciation, and quartz-grain signals have been partially reset during bioturbation. U-Pb ages on 273 zircon grains from the loess show prominent peaks at 1.6 and 1.8 Ga, as well as smaller numbers of grains from 1.0 to 1.6 Ga. These ages match dates from the Idefjord Terrane which comprises the bedrock of the study area. We argue that during ice-margin retreat, debris in the glacier was dominated by locally derived debris. This glacial sediment was left in thin patches uplands and particularly in large ice-marginal deltas. These deposits served as the proximal source for the loess. The presence of thin loess in Svartedalen suggests loess to be common in soils of southwest Sweden.
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