| 1. |
- Carlson, Elisabeth, et al.
(författare)
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Students´ Experiences of Participation in a Research Team : Evaluation of a Research-based Teaching Activity in HigherEducation
- 2022
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Ingår i: International Journal for the Scholarship of Teaching & Learning. - : Faculty Center at Georgia Southern University. - 1931-4744. ; 16:3
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Tidskriftsartikel (refereegranskat)abstract
- AbstractIn Sweden as well as internationally the teaching and research nexus has been described as the defining charac-teristics of higher education promoting generic skills such as information analysis and critical reflection. Vertically Integrated Projects has been proposed as one educational strategy where research and teaching are linked by in-viting students to take active part in actual research projects. The strategy is well aligned to Scholarship of teaching and learning enabling the transition from a teacher-centred accepted knowledge to a student-centred perspective where students are invited as producers of knowledge. The aim of the current study was to explore students’ experiences of participation in a research-based learning activity with academia and industrial partners, designed as a qualitative explorative study using focus group interviews. Findings describe not only factors students find motivating for learning, but also their experience of being part of professional life with its benefits and challenges.
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| 2. |
- Aeinehband, Shahin, et al.
(författare)
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Cerebrospinal fluid kynurenines in multiple sclerosis : relation to disease course and neurocognitive symptoms
- 2016
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Ingår i: Brain, behavior, and immunity. - : Elsevier. - 0889-1591 .- 1090-2139. ; 51, s. 47-55
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Tidskriftsartikel (refereegranskat)abstract
- Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system, with a high rate of neurocognitive symptoms for which the molecular background is still uncertain. There is accumulating evidence for dysregulation of the kynurenine pathway (KP) in different psychiatric and neurodegenerative conditions. We here report the first comprehensive analysis of cerebrospinal fluid (CSF) kynurenine metabolites in MS patients of different disease stages and in relation to neurocognitive symptoms. Levels of tryptophan (TRP), kynurenine (KYN), kynurenic acid (KYNA) and quinolinic acid (QUIN) were determined with liquid chromatography mass spectrometry in cell-free CSF. At the group level MS patients (cohort 1; n = 71) did not differ in absolute levels of TRP, KYN, KYNA or QUIN as compared to non-inflammatory neurological disease controls (n = 20). Stratification of patients into different disease courses revealed that both absolute QUIN levels and the QUIN/KYN ratio were increased in relapsing-remitting MS (RRMS) patients in relapse. Interestingly, secondary progressive MS (SPMS) displayed a trend for lower TRP and KYNA, while primary progressive (PPMS) patients displayed increased levels of all metabolites, similar to a group of inflammatory neurological disease controls (n = 13). In the second cohort (n = 48), MS patients with active disease and short disease duration were prospectively evaluated for neuropsychiatric symptoms. In a supervised multivariate analysis using orthogonal projection to latent structures (OPLS-DA) depressed patients displayed higher KYNA/TRP and KYN/TRP ratios, mainly due to low TRP levels. Still, this model had low predictive value and could not completely separate the clinically depressed patients from the non-depressed MS patients. No correlation was evident for other neurocognitive measures. Taken together these results demonstrate that clinical disease activity and differences in disease courses are reflected by changes in KP metabolites. Increased QUIN levels of RRMS patients in relapse and generally decreased levels of TRP in SPMS may relate to neurotoxicity and failure of remyelination, respectively. In contrast, PPMS patients displayed a more divergent pattern more resembling inflammatory conditions such as systemic lupus erythematosus. The pattern of KP metabolites in RRMS patients could not predict neurocognitive symptoms.
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| 3. |
- Axelsson, Per, 1972-, et al.
(författare)
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Inledning
- 2016
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Ingår i: Samiska Rötter. - Solna : Sveriges släktforskarförbund. - 9789188341037 ; , s. 5-7
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Bokkapitel (populärvet., debatt m.m.)
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| 4. |
- Berg, Martin, 1977-, et al.
(författare)
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Beräkningsmedier
- 2021
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Ingår i: Introduktion till medieteknik. - Lund : Studentlitteratur AB. - 9789144141671 ; , s. 261-269
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Vad kan falska nyheter, VR-glasögon och aktivitetsarmband lära oss om medieteknik som forskningsämne? Med utgångspunkt i tre forskningsbaserade exempel introducerar vi beräkningsmedier som ett nyckelbegrepp för framtida medieteknisk forskning. Begreppet bidrar till att ta fram digitala teknologiers datafierande karaktär och deras inflytande på relationen mellan människor och deras kroppar, mellan medier och vad som uppfattas vara verkligt i en medialiserad värld. Detta hjälper oss att bedriva vetenskaplig forskning inom ämnet medieteknik på sätt som både skapar förståelse för och bidrar till utvecklingen av digitala medier med hänsyn till deras tekniska, sociala, kulturella och ekonomiska förutsättningar.
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| 5. |
- Berg, Martin, 1977-, et al.
(författare)
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Inledning : Varför tekniska mediestudier?
- 2023. - 1
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Ingår i: Tekniska mediestudier. - Lund : Studentlitteratur AB. - 9789144155234 ; , s. 11-23
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 6. |
- Bolter, Jay David, et al.
(författare)
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Media studies, mobile augmented reality, and interaction design
- 2013
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Ingår i: interactions. - : ACM. - 1072-5520 .- 1558-3449. ; 20:1, s. 36-45
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- You are walking in the Sweetwater Creek State Park near Atlanta and using the Augmented Reality (AR) Trail Guide, a mobile application designed by Isaac Kulka for the Argon Browser (Figure 1). The application offers two views: a now familiar Google-style map, with points of interest marked on its surface, and an AR view, which shows these points located in space. You see the map view when you hold the screen parallel to the ground; when you turn the phone up to look at the world, you get the AR view with the points of interest floating in space in front of you. This simple gesture of raising the phone changes your relationship to the information. You pass from a fully symbolic form of representation to a form of perceiving symbolic information as part of your visual environment. The AR Trail Guide, developed in the Augmented Environments Lab at Georgia Tech [1], illustrates a new realm in AR design that goes beyond current commercial applications. In this article, we discuss some of these new areas, such as designing for experiences in cultural heritage, personal expression, and entertainment. At the same time, we want to address a larger issue. ACM interactions has often been a place for exploring new paradigms and the relevance for interaction design of unusual approaches from other disciplines. In that spirit, we pose the question: Can the humanistic discipline of media studies play a useful role in interaction design? Media studies looks at the history of media and their relationship to culture, and we will focus here on digital media and their relationship to other media, both present and past. Looking at digital media in a historical context is relevant because of the dynamic relationship between "traditional" media (film, television, radio, print) and their digital remediations. How can media studies be made to contribute to the productive work of interaction design? We believe one answer lies in using the historical understanding gained through media studies to develop a kind of media aesthetics that can guide designers as they explore new forms of digital media such as the mobile augmented reality application described above.
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| 7. |
- Bolter, Jay David, 1951-, et al.
(författare)
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Reality Media : Augmented and Virtual Reality
- 2021. - 1
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Bok (refereegranskat)abstract
- How augmented reality and virtual reality are taking their places in contemporary media culture alongside film and television.This book positions augmented reality (AR) and virtual reality (VR) firmly in contemporary media culture. The authors view AR and VR not as the latest hyped technologies but as media—the latest in a series of what they term “reality media,” taking their place alongside film and television. Reality media inserts a layer of media between us and our perception of the world; AR and VR do not replace reality but refashion a reality for us. Each reality medium mediates and remediates; each offers a new representation that we implicitly compare to our experience of the world in itself but also through other media.The authors show that as forms of reality media emerge, they not only chart a future path for media culture, but also redefine media past. With AR and VR in mind, then, we can recognize their precursors in eighteenth-century panoramas and the Broadway lights of the 1930s. A digital version of Reality Media, available through the book's website, invites readers to visit a series of virtual rooms featuring interactivity, 3-D models, videos, images, and texts that explore the themes of the book.
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| 8. |
- Claesson, Maria, 1985, et al.
(författare)
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Meso-ordered soft hydrogels
- 2012
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Ingår i: Soft Matter. - : Royal Society of Chemistry (RSC). - 1744-6848 .- 1744-683X. ; 8:31, s. 8149-8156
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Tidskriftsartikel (refereegranskat)abstract
- Many factors such as cross-link density are known to dictate the properties of hydrogels; however, less is known about the microstructure and how it can be tailored to control the properties. Here we demonstrate a method of forming microstructured hydrogels using a soft template that allows us to control and modify the microstructure. Meso-ordered hydrogels were formed by chemically cross-linking poly(ethylene glycol)-diacrylate (PEG-DA) segments via photopolymerization in the presence of poly(ethylene glycol)-poly(propylene glycol)-poly(ethylene glycol) (EOxPOyEOx) block copolymers. The results showed that hydrogels with lamellar mesostructured regions were formed when high concentrations of PEG-DA segments (50%) were used in combination with block co-polymers having certain ratios of the hydrophilic and hydrophobic blocks (P123, EO20PO70EO20). Only lamellar mesostructures were observed, independent of the PEG molecular weight (1500 or 3400 g mol(-1)) or block co-polymer concentration (10-50%). This finding demonstrates that it is possible to form soft meso-ordered hydrogels using block co-polymers as templates, and they do not follow the same mesophase behavior as the purely self-assembled block co-polymers.
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| 9. |
- Ekman-Ordeberg, Gunvor, et al.
(författare)
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Tafoxiparin, a novel drug candidate for cervical ripening and labor augmentation: results from 2 randomized, placebo-controlled studies
- 2024
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Ingår i: American Journal of Obstetrics and Gynecology. - 0002-9378 .- 1097-6868. ; 230:3
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Forskningsöversikt (refereegranskat)abstract
- Background: Slow progression of labor is a common obstetrical problem with multiple associated complications. Tafoxiparin is a depolymerized form of heparin with a molecular structure that eliminates the anticoagulant effects of heparin. We report on 2 phase II clinical studies of tafoxiparin in primiparas. Study 1 was an exploratory, first-in-pregnant-women study and study 2 was a dose-finding study. Objective: Study 1 was performed to explore the effects on labor time of subcutaneous administration of tafoxiparin before onset of labor. Study 2 was performed to test the hypothesis that intravenous treatment with tafoxiparin reduces the risk for prolonged labor after spontaneous labor onset in situations requiring oxytocin stimulation because of dystocia. Study Design: Both studies were randomized, double-blind, and placebo-controlled. Participants were healthy, nulliparous females aged 18 to 45 years with a normal singleton pregnancy and gestational age confirmed by ultrasound. The primary endpoints were time from onset of established labor (cervical dilation of 4 cm) until delivery (study 1) and time from start of study treatment infusion until delivery (study 2). In study 1, patients at 38 to 40 weeks of gestation received 60 mg tafoxiparin or placebo daily as 0.4 mL subcutaneous injections until labor onset (maximum 28 days). In study 2, patients experiencing slow progression of labor, a prolonged latent phase, or labor arrest received a placebo or 1 of 3 short-term tafoxiparin regimens (initial bolus 7, 21, or 35 mg followed by continuous infusion at 5, 15, or 25 mg/hour until delivery; maximum duration, 36 hours) in conjunction with oxytocin. Results: The number of participants randomized in study 1 was 263, and 361 were randomized in study 2. There were no statistically significant differences in the primary endpoints between those receiving tafoxiparin and those receiving the placebo in both studies. However, in study 1, the risk for having a labor time exceeding 12 hours was significantly reduced by tafoxiparin (tafoxiparin 6/114 [5%] vs placebo 18/101 [18%]; P=.0045). Post hoc analyses showed that women who underwent labor induction had a median (range) labor time of 4.44 (1.2–8.5) hours with tafoxiparin and 7.03 (1.5–14.3) hours with the placebo (P=.0041) and that co-administration of tafoxiparin potentiates the effect of oxytocin and facilitates a shorter labor time among women with a labor time exceeding 6 to 8 hours (P=.016). Among women induced into labor, tafoxiparin had a positive effect on cervical ripening in 11 of 13 cases (85%) compared with 3 of 13 participants (23%) who received the placebo (P=.004). For women requiring oxytocin because of slow progression of labor, the corresponding results were 34 of 51 participants (66%) vs 16 of 40 participants (40%) (P=.004). In study 2, tafoxiparin had no positive effects on the secondary endpoints when compared with the placebo. Except for injection-site reactions in study 1, adverse events were no more common for tafoxiparin than for the placebo among either mothers or infants. There were few serious or treatment-related adverse events. Conclusion: Subcutaneous treatment with tafoxiparin before labor onset (study 1) may be effective in reducing the labor time among women undergoing labor induction and among those requiring oxytocin for slow progression of labor. Moreover, tafoxiparin may have a positive effect on cervical ripening. Short-term, intravenous treatment with tafoxiparin as an adjunct to oxytocin in patients with labor arrest (study 2) did not affect labor time or other endpoints. Both studies suggest that tafoxiparin has a favorable safety profile in mothers and their infants.
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| 10. |
- ENGBERG, ARON, et al.
(författare)
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Evangelical Volunteers in Israel as Long-Term Pilgrims : Ambassadors for the Kingdom
- 2016
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Ingår i: Pilgrimage and Tourism to Holy Cities : Ideological and Management Perspectives - Ideological and Management Perspectives. - Wallingford : CABI Publishing. - 9781780647388 ; , s. 161-174
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Bokkapitel (refereegranskat)abstract
- Drawing from several years of field work and about 30 life story interviews,this chapter presents a case of contemporary evangelical mobility that cannotbe squarely placed within any of the related academic debates about ‘(religious)tourism’, ‘pilgrimage’, ‘short-term missions’, ‘international volunteering’ or ‘migration’ simply because it is intrinsically related to all these phenomena at the same time. Pro-Zionist Evangelical Christians come to Jerusalem from all parts of the world; some of them as part of biblical tours, some for Christian conferences or for Hebrew courses and yet others come as volunteers.This latter group is engaged in what often looks like secular humanitarian work, or sometimes even political activism, but explains these activities almost exclusively in religious terms. Initially, they come for a short period of time but often end up staying in Jerusalem for 10 years or more. What looks like a temporary adventure often turns out to be something more akin to a ‘way of life’. Thus, I will explore this phenomenon as a case of ‘long-term pilgrimage’ in order to discuss the religious meanings that the volunteers attach to their time in Israel, the practices that they are involved in and to the place itself. Apart from providing more data on contemporary religiously motivated travel patterns I hope that this case will prove useful in reconsidering the traditional boundaries between ‘tourism’, ‘volunteer work’ and ‘pilgrimage’, and perhaps also illuminate something of the underlying theoretical quagmires about the relationship between ‘the secular’ and ‘the religious’.
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