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- Blomstrom-Lundqvist, C., et al.
(author)
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European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections-endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)
- 2020
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In: European Heart Journal. - : Oxford University Press (OUP). - 0195-668X .- 1522-9645. ; 41:21, s. 2012-2032
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Journal article (peer-reviewed)abstract
- Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy devices are potentially lifesaving treatments for a number of cardiac conditions but are not without risk. Most concerning is the risk of a cardiac implantable electronic device (CIED) infection, which is associated with significant morbidity, increased hospitalizations, reduced survival, and increased health care costs. Recommended preventive strategies such as administration of intravenous antibiotics before implantation are well-recognized. Uncertainties have remained about the role of various preventive, diagnostic, and treatment measures such as skin antiseptics, pocket antibiotic solutions, antibacterial envelopes, prolonged antibiotics post-implantation, and others. When compared with previous guidelines or consensus statements, the present consensus document gives guidance on the use of novel device alternatives, novel oral anticoagulants, antibacterial envelopes, prolonged antibiotics post-implantation, as well as definitions on minimum quality requirements for centres and operators and volumes. The recognition that an international consensus document focused on management of CIED infections is lacking, the dissemination of results from new important randomized trials focusing on prevention of CIED infections, and observed divergences in managing device-related infections as found in an European Heart Rhythm Association worldwide survey, provided a strong incentive for a Novel 2019 International State-of-the-art Consensus document on risk assessment, prevention, diagnosis, and treatment of CIED infections.
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- David-Uraz, A., et al.
(author)
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Magnetic OB[A] Stars with TESS : probing their Evolutionary and Rotational properties (MOBSTER) - I. First-light observations of known magnetic B and A stars
- 2019
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In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 487:1, s. 304-317
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Journal article (peer-reviewed)abstract
- In this paper we introduce the MOBSTER collaboration and lay out its scientific goals. We present first results based on the analysis of 19 previously known magnetic O, B, and A stars observed in 2-min cadence in sectors 1 and 2 of the Transiting Exoplanet Survey Satellite (TESS) mission. We derive precise rotational periods from the newly obtained light curves and compare them to previously published values. We also discuss the overall photometric phenomenology of the known magnetic massive and intermediate-mass stars and propose an observational strategy to augment this population by taking advantage of the high-quality observations produced by TESS.
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- Shultz, M. E., et al.
(author)
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Ultraviolet spectropolarimetry with Polstar : using Polstar to test magnetospheric mass-loss quenching
- 2022
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In: Astrophysics and Space Science. - : Springer Nature. - 0004-640X .- 1572-946X. ; 367:12
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Journal article (peer-reviewed)abstract
- Polstar is a proposed NASA MIDEX space telescope that will provide high-resolution, simultaneous full-Stokes spectropolarimetry in the far ultraviolet, together with low-resolution linear polarimetry in the near ultraviolet. This observatory offers unprecedented capabilities to obtain unique information on the magnetic and plasma properties of the magnetospheres of hot stars. We describe an observing program making use of the known population of magnetic hot stars to test the fundamental hypothesis that magnetospheres should act to rapidly drain angular momentum, thereby spinning the star down, whilst simultaneously reducing the net mass-loss rate. Both effects are expected to lead to dramatic differences in the evolution of magnetic vs. non-magnetic stars.
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- Wolever, Thomas M S, et al.
(author)
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Measuring the glycemic index of foods: interlaboratory study.
- 2008
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In: The American journal of clinical nutrition. - 0002-9165 .- 1938-3207. ; 87:1
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Journal article (peer-reviewed)abstract
- BACKGROUND: Many laboratories offer glycemic index (GI) services. OBJECTIVE: We assessed the performance of the method used to measure GI. DESIGN: The GI of cheese-puffs and fruit-leather (centrally provided) was measured in 28 laboratories (n=311 subjects) by using the FAO/WHO method. The laboratories reported the results of their calculations and sent the raw data for recalculation centrally. RESULTS: Values for the incremental area under the curve (AUC) reported by 54% of the laboratories differed from central calculations. Because of this and other differences in data analysis, 19% of reported food GI values differed by >5 units from those calculated centrally. GI values in individual subjects were unrelated to age, sex, ethnicity, body mass index, or AUC but were negatively related to within-individual variation (P=0.033) expressed as the CV of the AUC for repeated reference food tests (refCV). The between-laboratory GI values (mean+/-SD) for cheese-puffs and fruit-leather were 74.3+/-10.5 and 33.2+/-7.2, respectively. The mean laboratory GI was related to refCV (P=0.003) and the type of restrictions on alcohol consumption before the test (P=0.006, r2=0.509 for model). The within-laboratory SD of GI was related to refCV (P<0.001), the glucose analysis method (P=0.010), whether glucose measures were duplicated (P=0.008), and restrictions on dinner the night before (P=0.013, r2=0.810 for model). CONCLUSIONS: The between-laboratory SD of the GI values is approximately 9. Standardized data analysis and low within-subject variation (refCV<30%) are required for accuracy. The results suggest that common misconceptions exist about which factors do and do not need to be controlled to improve precision. Controlled studies and cost-benefit analyses are needed to optimize GI methodology. The trial was registered at clinicaltrials.gov as NCT00260858.
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- Erba, C., et al.
(author)
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Confirmation of ξ1 CMa’s ultra-slow rotation : magnetic polarity reversal and a dramatic change in magnetospheric UV emission lines
- 2021
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In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press. - 0035-8711 .- 1365-2966. ; 506:2, s. 2296-2308
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Journal article (peer-reviewed)abstract
- The magnetic beta Cep pulsator xi(1) CMa has the longest rotational period of any known magnetic B-type star. It is also the only magnetic B-type star with magnetospheric emission that is known to be modulated by both rotation and pulsation. We report here the first unambiguous detection of a negative longitudinal magnetic field in xi(1) CMa (< B-z > = -87 +/- 2 G in 2019 and < B-z > = -207 +/- 3 G in 2020), as well as the results of ongoing monitoring of the star's H alpha variability. We examine evidence for deviation from a purely dipolar topology. We also report a new HST UV spectrum of xi(1) CMa obtained near magnetic null that is consistent with an equatorial view of the magnetosphere, as evidenced by its similarity to the UV spectrum of beta Cep obtained near maximum emission. The new UV spectrum of xi(1) CMa provides additional evidence for the extremely long rotation period of this star via comparison to archival data.
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- Slart, Riemer H. J. A., et al.
(author)
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Position paper of the EACVI and EANM on artificial intelligence applications in multimodality cardiovascular imaging using SPECT/CT, PET/CT, and cardiac CT
- 2021
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In: European Journal of Nuclear Medicine and Molecular Imaging. - : Springer. - 1619-7070 .- 1619-7089. ; 48:5, s. 1399-1413
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Journal article (peer-reviewed)abstract
- In daily clinical practice, clinicians integrate available data to ascertain the diagnostic and prognostic probability of a disease or clinical outcome for their patients. For patients with suspected or known cardiovascular disease, several anatomical and functional imaging techniques are commonly performed to aid this endeavor, including coronary computed tomography angiography (CCTA) and nuclear cardiology imaging. Continuous improvement in positron emission tomography (PET), single-photon emission computed tomography (SPECT), and CT hardware and software has resulted in improved diagnostic performance and wide implementation of these imaging techniques in daily clinical practice. However, the human ability to interpret, quantify, and integrate these data sets is limited. The identification of novel markers and application of machine learning (ML) algorithms, including deep learning (DL) to cardiovascular imaging techniques will further improve diagnosis and prognostication for patients with cardiovascular diseases. The goal of this position paper of the European Association of Nuclear Medicine (EANM) and the European Association of Cardiovascular Imaging (EACVI) is to provide an overview of the general concepts behind modern machine learning-based artificial intelligence, highlights currently prefered methods, practices, and computational models, and proposes new strategies to support the clinical application of ML in the field of cardiovascular imaging using nuclear cardiology (hybrid) and CT techniques.
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