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- Dynefors, Kristina, 1977, et al.
(författare)
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research and development of SiC Static Induction transistor
- 2003
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Ingår i: GHz2003 conference, Linköping 2003.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A fabrication process for SiC Static Induction Transistors (SITs) is developed and tested. Simulated and measured results of the device are presented. The complete fabrication process involves only 5 lithography steps, due to the self-aligned process used for mesa, ohmic contacts and gates. This makes the process fast and minimize the risk of process errors. Only optical lithography is used in the process, why dimensions are not optimised. Mesa widths of 2, 3, 4 and 5 µm are processed. Since the process is scalable, better performance can be expected with smaller widths achieved by the use electron beam lithography. Preliminary results indicate FET operation with a maximum current density of 110 mA/mm.
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- Eriksson, Joakim, 1977-
(författare)
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Coping with decisions on deviations in complex product development projects
- 2012
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- A strong need for resource efficiency within manufacturing companies have been driven extensively through pro-active planning and methods which have naturally resulted in an increased amount of strong couplings between product development projects, their activities, and resources. These strong couplings mean a high level of complexity where deviations are likely to occur on a regular basis which can spread quickly and have far reaching consequences. Praxis related to treatment of such deviations in product development projects has not been widely discussed. The subsequent question is therefore How are decisions on managing deviations made in practice?A Practice approach has been adopted in this research and led on to the use of context sensitive research methods in order to collect relevant data. The main amount of data has been gathered through one year of participant observations and document retrieval in a product development project. Also, a large amount of interviews have been used as a method for collecting data.38 deviations have been analysed through the identification of praxis which has been primarily analysed by three theories. The first theory, decision roles, has been used to clarify the different types of uncertainties people within complex product development projects need to manage in practice. The second theory, loosely coupled systems, shows how temporary organizing by loose couplings enables parallel management of both planned and unplanned activities when deviations occur. The third theory, Sensemaking, have been used to characterise processes related to different types of uncertainties.Conclusions are drawn regarding how people acts related to deviations are directly dependent on the types of uncertainties of the context as well as the situation itself. Uncertainties regarding choices, responsibilities, mobilization, and legitimization combined with the temporary organization leads to certain praxis patterns. The patterns can be used by project managers and other decision makers as a way of discussing temporary organization and how process emerge within the organization today, and how they would like resulting processes to be managed when deviations occur.
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- Eriksson, Joakim, 1977-, et al.
(författare)
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Decisions on managing project deviations in practice
- 2024
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Ingår i: International Journal of Project Organisation and Management. - : Inderscience Publishers. - 1740-2891 .- 1740-2905.
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents the results of a case study aimed at investigating how decisions are made on managing deviations in complex product development projects. The results are based on the analysis of data collected from participant observations, as well as interviews with project managers from seven large manufacturing companies. The data is analysed according to four types of sensemaking processes. This research examines why these processes are used in different situations and further explore their characteristics and at their relationship with the different roles decisions play in organizations. The factors driving controlled and uncontrolled sensemaking are also examined. This research contributes to knowledge of how project managers use different praxes to manage deviations in complex, socially and politically sensitive environments. The results can be used by decision makers within complex product development in order to assist them in managing deviations, proactively as well as reactively.
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- Botling, Johan, et al.
(författare)
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High-grade progression confers poor survival in pancreatic neuroendocrine tumors
- 2020
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Ingår i: Neuroendocrinology. - : S. Karger AG. - 0028-3835 .- 1423-0194. ; 110:11-12, s. 891-898
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Little is known about how Pancreatic Neuroendocrine Tumors (PanNETs) evolve over time and if changes towards a more aggressive biology correlates with prognosis. The purpose of this study was to characterize changes PanNET differentiation and proliferation over time, and to correlate findings to overall survival (OS).PATIENTS AND METHODS: In this retrospective cohort study we screened 475 PanNET patients treated at Uppsala University Hospital, Sweden. Sporadic patients with baseline and follow-up tumor samples were included. Pathology reports and available tissue sections were re-evaluated with regard to tumor histopathology and Ki-67 index.RESULTS: Forty-six patients with 106 tumor samples (56 available for pathology re-evaluation) were included. Median Ki-67 index at diagnosis was 7% (range 1-38%), grade 1 n=8, grade 2 n=36, and grade 3 n=2. The median change in Ki-67 index (absolute value; follow-up - baseline) was +14% (range -11 to +80%). Increase in tumor grade occurred in 28 patients (63.6%), the majority from grade 1/2 to grade 3 (n=24, 54.5%). The patients with a high-grade progression had a median OS of 50.2 months compared to 115.1 months in patients without such progression (HR 3.89, 95% CI 1.91-7.94, P<0.001).CONCLUSIONS: A longitudinal increase in Ki-67 index and increase in tumor grade were observed in a majority of PanNETs included in this study. We propose that increase in Ki-67 index and high-grade progression should be investigated further as important biomarkers in PanNET.
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