| 1. |
|
|
| 2. |
- Bag, Gargi, et al.
(författare)
-
Performance Evaluation of IEC 61850-90-5 over a latency optimized 3GPP LTE Network
- 2018
-
Ingår i: 2018 IEEE International Conference on Communications, Control, and Computing Technologies for Smart Grids, SmartGridComm 2018. - : IEEE. - 9781538679548
-
Konferensbidrag (refereegranskat)abstract
- This paper evaluates the performance of the IEC 61850-90-5 protocol stack transmitted over a latency optimized non-commercial 3GPP LTE network through experiments in a lab environment. IEC 61850-90-5 is designed for Phasor Measurement Unit (PMU) communication but can also be extended to other areas of control and protection in smart grids, using the routable GOOSE and routable sample value features. The test was carried out using a PC that emulated a PMU in sending periodic IEC61850-90-5 packets. Different IEC 61850-90-5 packet sizes and transmission rates were considered to determine the availability, throughput and latency of the LTE based network. The latency was minimized by applying a low latency scheduling mechanism and local breakout where user plane functionality of the core network is located at the edge of the Radio Access network. From the results it can be seen that an LTE network with latency optimized configuration performs well in terms of throughput and latency whereas a reference network without local breakout show significantly higher latency and jitter.
|
|
| 3. |
- Bengtsson, Johan, 1985, et al.
(författare)
-
Metaxa: Automated detection and discrimination among ribosomal small subunit (12S/16S/18S) sequences of archaea, bacteria, eukaryotes, mitochondria, and chloroplasts
- 2011
-
Ingår i: SocBiN Bioinformatics Conference, Helsinki, Finland, 2011.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The ribosomal small subunit (SSU) rRNA gene has emerged as an important genetic marker for taxonomic identification in environmental sequencing datasets. However, the gene is not only present in the nuclear genome of eukaryotes and the core genome of prokaryotes, but also in the mitochondria and chloroplasts of eukaryotes. The SSU genes in the core genome, mitochondria and chloroplast are conceptually paralogous and should in most situations not be aligned and analyzed jointly, e.g. when estimating species diversity. Identifying the origin of SSU sequences in complex sequence datasets is a time-consuming and largely manual undertaking. To ease this situation, we have created Metaxa, an automated software tool to extract full-length and partial SSU sequences from larger sequence datasets and assign them to an archaeal, bacte- rial, nuclear eukaryote, mitochondrial, or chloroplast origin. Metaxa very efficiently detects SSU sequences from fragments as short as 200 base pairs, and correctly classifies 97% of the identified genes at read lengths typically obtained from pyrosequencing. In addition, Metaxa shows a false positive rate of 0.00012% when run on random DNA fragments, showing the robustness of the method. We believe that this tool will be useful in microbial and evolutionary ecology as well as in metagenomics.
|
|
| 4. |
- Bengtsson-Palme, Johan, 1985, et al.
(författare)
-
Metaxa: a software tool for automated detection and discrimination among ribosomal small subunit (12S/16S/18S) sequences of archaea, bacteria, eukaryotes, mitochondria, and chloroplasts in metagenomes and environmental sequencing datasets
- 2011
-
Ingår i: Antonie van Leeuwenhoek: international journal of general and molecular microbiology. - : Springer Science and Business Media LLC. - 0003-6072 .- 1572-9699. ; 100:3, s. 471-475
-
Tidskriftsartikel (refereegranskat)abstract
- The ribosomal small subunit (SSU) rRNA gene has emerged as an important genetic marker for taxonomic identification in environmental sequencing datasets. In addition to being present in the nucleus of eukaryotes and the core genome of prokaryotes, the gene is also found in the mitochondria of eukaryotes and in the chloroplasts of photosynthetic eukaryotes. These three sets of genes are conceptually paralogous and should in most situations not be aligned and analyzed jointly. To identify the origin of SSU sequences in complex sequence datasets has hitherto been a time-consuming and largely manual undertaking. However, the present study introduces Metaxa (http://microbiology.se/software/metaxa/), an automated software tool to extract full-length and partial SSU sequences from larger sequence datasets and assign them to an archaeal, bacterial, nuclear eukaryote, mitochondrial, or chloroplast origin. Using data from reference databases and from full-length organelle and organism genomes, we show that Metaxa detects and scores SSU sequences for origin with very low proportions of false positives and negatives. We believe that this tool will be useful in microbial and evolutionary ecology as well as in metagenomics.
|
|
| 5. |
- Engelbak Nielsen, Zandra, et al.
(författare)
-
Are cancer patients better off if they participate in clinical trials? : A mixed methods study
- 2020
-
Ingår i: BMC Cancer. - : Springer Science and Business Media LLC. - 1471-2407. ; 20:1
-
Tidskriftsartikel (refereegranskat)abstract
- BackgroundResearch and cancer care are closely intertwined; however, it is not clear whether physicians and nurses believe that clinical trials offer the best treatment for patients and, if so, whether this belief is justified. The aim of this study was therefore: (i) to explore how physicians and nurses perceive the benefits of clinical trial participation compared with standard care and (ii) whether it is justified to claim that clinical trial participation improves outcomes for cancer patients.MethodsA mixed methods approach was used employing semi-structured interviews with 57 physicians and nurses in oncology and haematology and a literature review of the evidence for trial superiority, i.e. the idea that receiving treatment in a clinical trial leads to a better outcome compared with standard care. Inductive thematic analysis was used to examine the interview data. A literature review comprising nine articles was conducted according to a conceptual framework developed by Peppercorn et al. and evaluated recent evidence on trial superiority.ResultsOur findings show that many physicians and nurses make claims supporting trial superiority, however very little evidence is available in the literature comparing outcomes for trial participants and non-participants that supports their assertions.ConclusionsDespite the recent rapid development and use of targeted therapy and immunotherapy, we find no support for trial participation to provide better outcomes for cancer patients than standard care. Hence, our present results are in line with previous results from Peppercorn et al. A weaker version of the superiority claim is that even if a trial does not bring about a direct positive effect, it brings about indirect positive effects. However, as the value of such indirect effects is dependent on the individual’s specific circumstances and preferences, their existence cannot establish the general claim that treatment in trials is superior. Belief in trial superiority is therefore unfounded. Hence, if such beliefs are communicated to patients in a trial recruitment context, it would provide misleading information. Instead emphasis should be on patients volunteering to give an altruistic contribution to the furthering of knowledge and to the potential benefit of future patients.
|
|
| 6. |
- Eriksson, Emelie, 1987-
(författare)
-
Patterns of corporate visual selfrepresentation in accounting narratives
- 2017
-
Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation deals with firms’ visual and pre-visual self-representations in accounting narratives. Self-representations are those descriptions about the company that firms include in accounting narratives to convey the current standings and their identity. External stakeholders increasingly expect non-numerical information about firms to be disclosed, and accounting narratives are a key medium for firms to account for their activities and maintain legitimacy as social actors. The question of which reporting conventions exist for legitimating selfrepresentations, especially from a visual perspective, remains unexplored. The purpose of this study is therefore to explore the empirical phenomenon of self-representations in accounting narratives in relation to legitimation rhetoric.The study is based on three research papers dealing with different patterns of self-representations in accounting-related narratives, including corporate reporting and business model diagrams. The examples are viewed through the theoretical lenses of semiotics and institutional theory, particularly legitimation theory. The study combines visual methods (visual content analysis and visual taxonomy) with other methods (interviews, text analysis) to conceptualize and exemplify what is meant by self-representations in accounting narratives. The study finds that there may be multiple parallel pre-visual self-representations at play to influence representations of the self, that visual self-representations are becoming more common in accounting narratives, and that several rhetorical strategies for legitimation are observable in these representations. By showing how diagrams can serve a legitimating purpose in accounting narratives, it is argued that diagrams should be considered on par with graphs and photographs as visual rhetorical devices in accounting narratives, and that they could be used as key communicative elements in the accounting process.Second, based on the longitudinal and comparative examples of self-representations, it is suggested that self-representations increasingly refer to abstract rather than concrete referents. This change is discussed in terms of the increasingly digital and service-based knowledge economy, where material referents give way to “amaterial” values. The contribution of this study is to describe selfrepresentations through several empirical examples, and to thereby increase awareness among practitioners and researchers of how visuals serve as communicative resources with legitimating functions in accounting narratives. Four concepts are proposed as tools for explaining the observed developments, and for improving visual literacy with regard to accounting narratives: inclusive perspective on accounting narratives, amateriality, self-representation, and diagrams.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Eriksson, Petri
(författare)
-
The effects of neurotrophic substances on primary sensory neurons following peripheral nerve injury
- 1997
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Sensory impulses from the periphery is transmitted by primary sensory neurons located in dorsal root and cranial nerve ganglia. The primary sensory neurons are phenotypically diverse with regard to their expression of various chemical components. Thus, various subpopulations of dorsal root ganglion (DRG) cells express the peptides substance P (SP) and calcitonin gene related peptide (CGRP), the enzyme fluoride-resistant acid phosphatase (FRAP) and bind the lectin Griffonia (Bandeiraea) simplicifolia I (B4), or the enzyme carbonic anhydrase II (CAII). Injury to peripheral sensory axons results in prominent changes in the cell bodies as well in the central termination areas of the affected primary sensory neuron. A significant fraction of the DRG cells downregulate SP, CGRP, FRAP and CAII and some undergo neuronal death. There is also changes in the termination pattern of afferents in the dorsal horn. Depletion of normally available target derived trophic factors seems to play an important role in the neuronal changes following axotomy. The effect of nerve growth factor (NGF) is mediated through the TrkA receptor whereas TrkB and TrkC interact with the neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), respectively. NGF, BDNF and NT-3 have been shown to have distinct and overlapping effects on the survival and differentiation of sensory neurons and motoneurons and have been proposed as critical target-derived factors. Various sciatic nerve injuries in female but not male rats lead to a significant decrease in DRG numbers. This loss is not affected by increasing age. Even a short-term or delayed NGF application was able to counteract the loss of DRG neurons following axotomy. NGF also restored the depletion of SP, CGRP and to some extent that of FRAP, but did not affect B4-binding or CAII. However, the same NGF-dose that rescued the axotomized DRG neurons was not sufficient to reduce the axotomy-induced depletion in SP and CGRP. Three weeks of treatment with BDNF or NT-3 rescued axotomized neonatal DRG neurons, but not motoneurons. The activation of microglial and astroglial cells occurs already twenty-four hours, peak around one week after injury whereafter follows a considerably slower decrease. NGF application in doses sufficient to reduce neuronal death and neuropeptide depletion could not counteract the glial cell reactions. NGF, but not BDNF and NT-3 was found to counteract the axotomy-induced expansion of myelinated afferents into lamina II. In conclusion, the results show that the loss of DRG neurons and some of the biochemical and central connectivity changes after a peripheral nerve injury can be counteracted by application of NGF, BDNF or NT-3. The non-neuronal cells as well as some non-peptidergic biochemical changes cannot be affected, however. These findings indicate that exogenous neurotrophins influence the response of axotomized DRG neurons in a manner which may be significant for the functional recovery after peripheral nerve injury.
|
|
| 10. |
- Eriksson, Thommy, 1967, et al.
(författare)
-
Audiovisual Thinking
- 2010
-
Ingår i: Media, Communication and Cultural Studies (MeCCSA).
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)
|
|
