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Sökning: WFRF:(Escobar Alfonso)

  • Resultat 1-6 av 6
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1.
  • Cohen, Lois K, et al. (författare)
  • Dentistry's future.
  • 2018
  • Ingår i: Journal of the American Dental Association. - : Elsevier BV. - 1943-4723 .- 0002-8177. ; 149:9, s. 752-753
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
  •  
2.
  • Cohen, Lois K, et al. (författare)
  • Why a radical overhaul of dentistry is needed.
  • 2017
  • Ingår i: Indian journal of dental research : official publication of Indian Society for Dental Research. - 1998-3603. ; 28:5, s. 471-474
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
  •  
3.
  • Ortigoza-Escobar, Juan Darío, et al. (författare)
  • Free-thiamine is a potential biomarker of thiamine transporter-2 deficiency: a treatable cause of Leigh syndrome.
  • 2016
  • Ingår i: Brain : a journal of neurology. - : Oxford University Press (OUP). - 1460-2156. ; 139:Pt 1, s. 31-8
  • Tidskriftsartikel (refereegranskat)abstract
    • Thiamine transporter-2 deficiency is caused by mutations in the SLC19A3 gene. As opposed to other causes of Leigh syndrome, early administration of thiamine and biotin has a dramatic and immediate clinical effect. New biochemical markers are needed to aid in early diagnosis and timely therapeutic intervention. Thiamine derivatives were analysed by high performance liquid chromatography in 106 whole blood and 38 cerebrospinal fluid samples from paediatric controls, 16 cerebrospinal fluid samples from patients with Leigh syndrome, six of whom harboured mutations in the SLC19A3 gene, and 49 patients with other neurological disorders. Free-thiamine was remarkably reduced in the cerebrospinal fluid of five SLC19A3 patients before treatment. In contrast, free-thiamine was slightly decreased in 15.2% of patients with other neurological conditions, and above the reference range in one SLC19A3 patient on thiamine supplementation. We also observed a severe deficiency of free-thiamine and low levels of thiamine diphosphate in fibroblasts from SLC19A3 patients. Surprisingly, pyruvate dehydrogenase activity and mitochondrial substrate oxidation rates were within the control range. Thiamine derivatives normalized after the addition of thiamine to the culture medium. In conclusion, we found a profound deficiency of free-thiamine in the CSF and fibroblasts of patients with thiamine transporter-2 deficiency. Thiamine supplementation led to clinical improvement in patients early treated and restored thiamine values in fibroblasts and cerebrospinal fluid.
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4.
  • Pinedo-Escobar, José Alfonso, et al. (författare)
  • Nanoparticulate Double-Heterojunction Photocatalysts Comprising TiO2(Anatase)/WO3/TiO2(Rutile) with Enhanced Photocatalytic Activity toward the Degradation of Methyl Orange under Near-Ultraviolet and Visible Light
  • 2021
  • Ingår i: ACS Omega. - : American Chemical Society (ACS). - 2470-1343. ; 6:18, s. 11840-11848
  • Tidskriftsartikel (refereegranskat)abstract
    • Nanoparticulate double-heterojunction photocatalysts comprising TiO2(Anatase)/WO3/TiO2(Rutile) were produced by a sol–gel method. The resulting photocatalysts exhibit clear synergistic effects when tested toward the degradation of methyl orange under both UV and visible light. Kinetic studies indicate that the degradation rate on the best double-heterojunction photocatalyst (10 wt % WO3-TiO2) depends mainly on the amount of dye concentration, contrary to pure oxides in which the degradation rate is limited by diffusion-controlled processes. The synergistic effects were confirmed through systematic and careful studies including holes and OH radical formation, X-ray diffraction, electron microscopy, elemental analysis, UV–vis diffuse reflectance spectroscopy, and surface area analysis. Our results indicate that the successful formation of a double heterojunction in the TiO2(Anatase)/WO3/TiO2(Rutile) system leads to enhanced photoactivity when compared to individual oxides and commercial TiO2 P25.
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5.
  • Bravo, L, et al. (författare)
  • 2021
  • swepub:Mat__t
  •  
6.
  • Tabiri, S, et al. (författare)
  • 2021
  • swepub:Mat__t
  •  
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  • Resultat 1-6 av 6

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