| 1. |
- Scarlata, Simone, et al.
(författare)
-
Advancing healthcare through thoracic ultrasound research in older patients
- 2023
-
Ingår i: Aging Clinical and Experimental Research. - 1594-0667 .- 1720-8319. ; 35:12, s. 2887-2901
-
Forskningsöversikt (refereegranskat)abstract
- This paper reports the proceedings of a meeting convened by the Research Group on Thoracic Ultrasound in Older People of the Italian Society of Gerontology and Geriatrics, to discuss the current state-of-the-art of clinical research in the field of geriatric thoracic ultrasound and identify unmet research needs and potential areas of development. In the last decade, point-of-care thoracic ultrasound has entered clinical practice for diagnosis and management of several respiratory illnesses, such as bacterial and viral pneumonia, pleural effusion, acute heart failure, and pneumothorax, especially in the emergency–urgency setting. Very few studies, however, have been specifically focused on older patients with frailty and multi-morbidity, who frequently exhibit complex clinical pictures needing multidimensional evaluation. At the present state of knowledge, there is still uncertainty on the best requirements of ultrasound equipment, methodology of examination, and reporting needed to optimize the advantages of thoracic ultrasound implementation in the care of geriatric patients. Other issues regard differential diagnosis between bacterial and aspiration pneumonia, objective grading of interstitial syndrome severity, quantification and monitoring of pleural effusions and solid pleural lesions, significance of ultrasonographic assessment of post-COVID-19 sequelae, and prognostic value of assessment of diaphragmatic thickness and motility. Finally, application of remote ultrasound diagnostics in the community and nursing home setting is still poorly investigated by the current literature. Overall, the presence of several open questions on geriatric applications of thoracic ultrasound represents a strong call to implement clinical research in this field.
|
|
| 3. |
- Borrarzo, Cristian, et al.
(författare)
-
Monte Carlo Simulation to Evaluate Factors Affecting Imaging Performances of Compact Scintillation Gamma Camara
- 2016
-
Ingår i: 2016 IEEE NUCLEAR SCIENCE SYMPOSIUM, MEDICAL IMAGING CONFERENCE AND ROOM-TEMPERATURE SEMICONDUCTOR DETECTOR WORKSHOP (NSS/MIC/RTSD). - : IEEE. - 9781509016426
-
Konferensbidrag (refereegranskat)abstract
- In recent years, a new generation of compact gamma cameras, based on monolithic scintillation crystals, has become increasingly widespread. The main advantages of small FoV gamma cameras with respect to the standard ones are high portability, low cost and low weight, allowing several clinical applications, from scintimammography to intraoperative tumor localization. In gamma cameras based on continuous scintillation crystals, intrinsic Spatial Resolution (SR) is mainly affected by two factors: scintillation light collection efficiency and overall crystal thickness. The first affects the counting statistics, the latter impacts on the light distribution width. To fully investigate the potentiality of these devices we took advantage of Monte Carlo simulations as a valuable tool to physically characterize the imaging systems and to establish a priori reference values. GEANT4 toolkit allows to completely describe the phenomenon of light emission and propagation through the media, providing control to all second-order factors existing in real systems. Results show clearly that SR is dependent on the number of photoelectrons produced and on the light spread. Furthermore, the role of refractive index has been unambiguously identified as an important factor affecting light collection and consequently SR.
|
|
