| 1. |
- Khaldi, Alexandre, 1982-, et al.
(author)
-
Patterning highly conducting conjugated polymer electrodes for soft and flexible microelectrochemical devices
- 2018
-
In: ACS Applied Materials and Interfaces. - : American Chemical Society (ACS). - 1944-8244 .- 1944-8252. ; 10:17, s. 14978-14985
-
Journal article (peer-reviewed)abstract
- There is a need for soft actuators in various biomedical applications in order to manipulate delicate objects such as cells and tissues. Soft actuators are able to adapt to any shape and limit the stress applied to delicate objects. Conjugated polymer actuators, especially in the so-called trilayer configuration, are interesting candidates for driving such micromanipulators. However, challenges involved in patterning the electrodes in a trilayer with individual contact have prevented further development of soft micromanipulators based on conjugated polymer actuators. To allow such patterning, two printing-based patterning techniques have been developed. First an oxidant layer is printed using either syringe-based printing or micro-contact printing, followed by vapor phase polymerization of the conjugated polymer. Sub-millimeter patterns with electronic conductivities of 800 Scm-1 are obtained. Next, laser ablation is used to cleanly cut the final device structures including the printed patterns, resulting in fingers with individually controllable digits and miniaturized hands. The methods presented in this paper will enable integration of patterned electrically active conjugated polymer layers in many types of complex 3-D structures.
|
|
| 2. |
|
|
| 3. |
- Alimelli, Adriano, et al.
(author)
-
Fish freshness detection by a computer screen photoassisted based gas sensor array
- 2007
-
In: Analytica Chimica Acta. - : Elsevier BV. - 0003-2670 .- 1873-4324. ; 582:2, s. 320-328
-
Journal article (peer-reviewed)abstract
- In the last years a large number of different measurement methodologies were applied to measure the freshness of fishes. Among them the connection between freshness and headspace composition has been considered by gas chromatographic analysis and from the last two decades by a number of sensors and biosensors aimed at measuring some characteristic indicators (usually amines). More recently also the so-called artificial olfaction systems gathering together many non-specific sensors have shown a certain capability to transduce the global composition of the fish headspace capturing the differences between fresh and spoiled products. One of the main objectives related to the introduction of sensor systems with respect to the analytical methods is the claimed possibility to distribute the freshness control since sensors are expected to be "portable" and "simple". In spite of these objectives, until now sensor systems did not result in any tool that may be broadly distributed. In this paper, we present a chemical sensor array where the optical features of layers of chemicals, sensitive to volatile compounds typical of spoilage processes in fish, are interrogated by a very simple platform based on a computer screen and a web cam. An array of metalloporphyrins is here used to classify fillets of thawed fishes according to their storage days and to monitor the spoilage in filleted anchovies for a time of 8 h. Results indicate a complete identification of the storage days of thawed fillets and a determination of the storage time of anchovies held at room temperature with a root mean square error of validation of about 30 min. The optical system produces a sort of spectral fingerprint containing information about both the absorbance and the emission of the sensitive layer. The system here illustrated, based on computer peripherals, can be easily scaled to any device endowed with a programmable screen and a camera such as cellular phones offering for the first time the possibility to fulfil the sensor expectation of diffused and efficient analytical capabilities. © 2006 Elsevier B.V. All rights reserved.
|
|
| 4. |
- Anderson, Tony, 1973-, et al.
(author)
-
Frog melanophores cultured on fluorescent microbeads : Biomimic-based biosensing
- 2005
-
In: Biosensors & bioelectronics. - : Elsevier BV. - 0956-5663 .- 1873-4235. ; 21:1, s. 111-120
-
Journal article (peer-reviewed)abstract
- Melanophores are pigmented cells in lower vertebrates capable of quick color changes and thereby suitable as whole cell biosensors. In the frog dermis skin layer, the large and dark pigmented melanophore surrounds a core of other pigmented cells. Upon hormonal stimulation the black-brown pigment organelles will redistribute within the melanophore, and thereby cover or uncover the core, making complex color changes possible in the dermis. Previously, melanophores have only been cultured on flat surfaces. Here we mimic the three dimensional biological geometry in the frog dermis by culturing melanophores on fluorescent plastic microbeads. To demonstrate biosensing we use the hormones melatonin and α-melanocyte stimulating hormone (α-MSH) as lightening or darkening stimuli, respectively. Cellular responses were successfully demonstrated on single cell level by fluorescence microscopy, and in cell suspension by a fluorescence microplate reader and a previously demonstrated computer screen photo-assisted technique. The demonstrated principle is the first step towards "single well/multiple read-out" biosensor arrays based on suspensions of different selective-responding melanophores, each cultured on microbeads with distinctive spectral characteristics. By applying small amount of a clinical sample, or a candidate substance in early drug screening, to a single well containing combinations of melanophores on beads, multiple parameter read-outs will be possible. © 2004 Elsevier B.V. All rights reserved.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
- Arwin, Hans, 1950-, et al.
(author)
-
Computer screen photo-assisted measurement of intensity or polarization change of light upon interaction with a sample
- 2006
-
Patent (pop. science, debate, etc.)abstract
- A method for measuring a property of a test sample utilizing one of the test methods ellipsometry, surface plasmon resonance and nephelometry, wherein the method includes the steps; providing a test sample being an object with which an optical interaction with light takes place, illuminating said test sample using a program controlled display as a light source, which program controlled display is composed of at least one activated pixel providing an illumination from an illuminating area of said program controlled display, arranging said program controlled display to illuminate said test sample with polarized light, detecting light emerging from said test sample utilizing a detector coupled to said program and evaluating said property from signals from said detector.
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
- Bakker, Jimmy W.P., et al.
(author)
-
Immunodetection using computer screen photo-assisted ellipsometry
- 2008
-
In: Physica Status Solidi. C: Current Topics in Solid State Physics. - Weinheim, Germany : Wiley-VCH Verlagsgesellschaft. - 1862-6351. ; 5:5, s. 1431-1433
-
Journal article (peer-reviewed)abstract
- Detection of antibody-antigen reactions is demonstrated by measuring changes in reflectance of light polarized parallel to the plane of incidence, using a computer screen as light source and a web camera as detector, giving results similar to traditional off-null ellipsometry and in accordance with a simplified theoretical model.
|
|
