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Sökning: WFRF:(Fischler H.)

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  • Fischler, H., et al. (författare)
  • Concept mapping as a tool for research in science education
  • 2001
  • Ingår i: Research in Science Education - Past, Present, and Future. - 0792367553
  • Bokkapitel (populärvet., debatt m.m.)abstract
    • In recent years concept mapping has become a powerful tool that is frequently applied in different contexts in science education. There are still, however, questions and problems that arise when researchers in science education begin to design concept map formats and search for appropriate methods of analysis. In a symposium, five research groups from different countries shared experiences of using concept maps and hence provided some answers to the questions and some illumination of the problems.
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  • Malenicka, S., et al. (författare)
  • Impaired intention-to-treat survival after listing for liver transplantation in children with biliary atresia compared to other chronic liver diseases : 20 years' experience from the Nordic countries
  • 2017
  • Ingår i: Pediatric Transplantation. - : Wiley. - 1397-3142 .- 1399-3046. ; 21:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Biliary atresia (BA) is the most common indication for LT in children. We investigated whether this diagnosis per se, compared to other chronic liver diseases (OCLD), had an influence on patient survival. Data from 421 Scandinavian children, 194 with BA and 227 with OCLD, listed for LT between 1990 and 2010 were analyzed. The intention-to-treat survival and influencing risk factors were studied. Patients with BA had higher risk of death after listing than patients with OCLD. The youngest (< 1 year) and smallest (< 10 kg) children with the highest bilirubin (> 510 mu mol/L), highest INR (> 1.6), and highest PELD score (> 20) listed during 1990s had the worst outcome. Given the same PELD score, patients with BA had higher risk of death than patients with OCLD. For adolescents, low weight/BMI was the only prognostic marker. Impaired intention-to-treat survival in patients with BA was mainly explained by more advanced liver disease in younger ages and higher proportion of young children in the BA group rather than diagnosis per se. PELD score predicted death, but seemed to underestimate the severity of liver disease in patients with BA. Poor nutritional status and severe cholestasis had negative impact on survival, supporting the "sickest children first" allocation policy and correction of malnutrition before surgery.
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