| 1. |
- Proletov, Ian, et al.
(författare)
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Primary and secondary glomerulonephritides 1.
- 2014
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Ingår i: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 1460-2385. ; 29 Suppl 3:May, s. 186-200
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Fodor, George A., 1954-, et al.
(författare)
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The implications of the object/unified modeling language approach to the problem of fault detection and isolation in dynamical systems
- 1999
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Ingår i: Proceedings of the 1999 IEEE International Symposium on Computer Aided Control System Design. - New York, USA : IEEE conference proceedings. - 0780355008 ; , s. 176-181
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Konferensbidrag (refereegranskat)abstract
- There is a growing trend to use object-based implementations and modeling in industrial control applications. However, the object-based approach imposes new theoretical and practical problems. Those problems are due to a higher abstraction level that is achievable with objects as compared to the more traditional, state-based fault detection and isolation methods (FDI) approaches. This paper presents a description of the problems and solutions to them in the framework of a discrete FDI method referred to as ontological control. The results are also relevant in respect to domain-independent failure recovery methods... (Fodor et al., 1997)
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| 4. |
- Fodor, George, 1954-, et al.
(författare)
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Modeling the real-time recovery of complex control systems : A fuzzy approach
- 1997
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Ingår i: 1997 IEEE International Conference on Systems, Man, and Cybernetics. - New York, USA : IEEE conference proceedings. - 0780340531 ; , s. 2163-2168
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Konferensbidrag (refereegranskat)abstract
- This paper presents an approach to complex system recovery based on a fuzzy specification method. The method can be applied when controllers of different types and makes are connected in a common control architecture. The method allows a controller B to trigger a recovery operation on a controller A when B has the recovery specification of A. The approach has important potential applications in industry, e.g. as a possible complement to PLC standards such as IEC1131, and to the design of hybrid and complex control systems
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| 5. |
- Grantner, Janos L., et al.
(författare)
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Applications of the Fuzzy State Fuzzy Output Finite State Machine to the Problem of Recovery from Violation of Ontological Assumptions
- 2000
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Ingår i: International Journal of Smart Engineering System Design. - : Taylor & Francis Group. - 1025-5818. ; 2:3, s. 177-199
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Tidskriftsartikel (refereegranskat)abstract
- A programmable logic controller (PC) carries out a control algorithm under violations of theontological assumptions (VOA) when the plant does not meet one or more unstated but essential assumptions used in the design of the control algorithm. This paper presents a recovery technique based on the theory of Fuzzy State Fuzzy Output Finite State Machines (FSFO-FSM). The appeal of this approach is that the only known recovery results today are for fuzzy controllers. A common drawback of most linguistic models is that they are essentially static and thus not suitable to model the sequential behavior of a PC program. A FSFO-FSM can act as a sequentialmachine during the normal course of control, yet it possesses all the required linguistic properties during a VOA. This approach can enhance substantially the safety and operational range of existing PC and embedded control applications. This paper describes the control problem, presents results based on simulations, and show architectural constraints when applying this principle to real-world application.
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| 6. |
- Grantner, J.L., et al.
(författare)
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Hybrid fuzzy-Boolean automata for ontological controllers
- 1998
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Ingår i: The 1998 IEEE International Conference on Fuzzy Systems Proceedings. - New York, USA : IEEE conference proceedings. - 078034863X ; , s. 400-404
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Konferensbidrag (refereegranskat)abstract
- This paper introduces a hybrid fuzzy-Boolean finite state machine (HFB FSM) model for ontological control. Ontological control is a novel type supervisory control that deals with the problems of error detection and recovery in complex control systems. The HFB FSM is used as a specification method for the problem of recovery when an autonomous control system encounters unexpected changes in its environment. The method allows a controller B (the ontological controller) to trigger a recovery operation on controller A when B has the recovery specification of A. The approach has important potential applications in industry
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| 7. |
- Grantner, Janos L., et al.
(författare)
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The virtual fuzzy state machine approach : a domain-independent fault detection and recovery method for object-based control systems
- 1999
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Ingår i: Proceedings of the 18th International Conference of the North American Fuzzy Information Processing Society (NAFIPS). - : IEEE conference proceedings. - 0780352114 ; , s. 158-162
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Konferensbidrag (refereegranskat)abstract
- The current trend of using object based design for real time control systems has the implication that traditional state based fault detection and recovery methods cannot be used directly. This problem is even more difficult for domain independent fault detection and recovery since most such methods are based on a formal analysis of the global state set. The paper presents a domain independent fault isolation, detection and recovery method for object based control systems based on constraints of the object architecture. Variations of the control behavior from normal cases are detected using a fuzzy state machine approach
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| 8. |
- Grantner, Janos L., et al.
(författare)
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Using fuzzy logic for bounded recovery of autonomous agents
- 1997
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Ingår i: 1997 Annual Meeting of the North American Fuzzy Information Processing Society. - New York, USA : IEEE conference proceedings. ; , s. 317-322
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Konferensbidrag (refereegranskat)abstract
- The solution to the problem of application-independent fault recovery of autonomous agents requires a specification method for the agent's capacity to act outside of its normal operational limits. This paper presents a recovery method based upon the theory of a fuzzy finite state machine. A fuzzy specification is given for the bounds within which an autonomous agent is capable to recover after an unexpected situation has occurred in its environment. It has been shown that the three main components of the recovery problem: fault detection, fault recovery, and the properties of the actuator/sensor gear of an autonomous agent are interrelated. The suggested method can be implemented either by an application-independent software algorithm, or by fuzzy logic hardware
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| 9. |
- Lonn, Eva, et al.
(författare)
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Novel Approaches in Primary Cardiovascular Disease Prevention : The HOPE-3 Trial Rationale, Design, and Participants' Baseline Characteristics.
- 2016
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Ingår i: Canadian Journal of Cardiology. - : Elsevier BV. - 0828-282X .- 1916-7075. ; 32:3, s. 311-318
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Cholesterol and blood pressure (BP) can be effectively and safely lowered with statin drugs and BP-lowering drugs, reducing major cardiovascular (CV) events by 20%-30% within 5 years in high-risk individuals. However, there are limited data in lower-risk populations. The Heart Outcomes Prevention Evaluation-3 (HOPE-3) trial is evaluating whether cholesterol lowering with a statin drug, BP lowering with low doses of 2 antihypertensive agents, and their combination safely reduce major CV events in individuals at intermediate risk who have had no previous vascular events and have average cholesterol and BP levels.METHODS: A total of 12,705 women 65 years or older and men 55 years or older with at least 1 CV risk factor, no known CV disease, and without any clear indication or contraindication to the study drugs were randomized to rosuvastatin 10 mg/d or placebo and to candesartan/hydrochlorothiazide 16/12.5 mg/d or placebo (2 × 2 factorial design) and will be followed for a mean of 5.8 years. The coprimary study outcomes are the composite of CV death, nonfatal myocardial infarction (MI), and nonfatal stroke and the composite of CV death, nonfatal MI, nonfatal stroke, resuscitated cardiac arrest, heart failure, and arterial revascularization.RESULTS: Participants were recruited from 21 countries in North America, South America, Europe, Asia, and Australia. Mean age at randomization was 66 years and 46% were women.CONCLUSIONS: The HOPE-3 trial will provide new information on cholesterol and BP lowering in intermediate-risk populations with average cholesterol and BP levels and is expected to inform approaches to primary prevention worldwide.
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| 10. |
- Mann, Johannes F. E., et al.
(författare)
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Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease : results of the renal Hope-2 study
- 2008
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Ingår i: Nephrology, Dialysis and Transplantation. - : Oxford University Press (OUP). - 0931-0509 .- 1460-2385. ; 23:2, s. 645-653
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Elevated plasma homocysteine levels are reported to be associated with higher rates of vascular diseases. Plasma homocysteine increases in chronic kidney disease (CKD) and could contribute to the increased cardiovascular risk in CKD. METHODS: Participants aged 55 years or older with CKD, defined as estimated GFR<60 ml/min and at high cardiovascular risk, were randomly assigned to the combination of folic acid, 2.5 mg, vitamin B6, 50 mg and vitamin B12, 1 mg (n = 307) or placebo (n = 312) daily for 5 years. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction and stroke. RESULTS: Mean baseline plasma homocysteine was 15.9 +/- 7.3 micromol/l in the active treatment group and 15.7 +/- 5.7 micromol/l in placebo group and decreased to 11.9 +/- 3.3 micromol/l (P < 0.001) on active treatment (15.5 +/- 4.5 on placebo). Primary outcome events occurred in 90 participants (29.3%) on active therapy and in 80 (25.6%) on placebo (relative risk, 1.19; 95% confidence interval, 0.88-1.61; P = 0.25). There were no significant treatment benefits on death from cardiovascular causes (1.24; 0.84-1.83), myocardial infarction (1.10; 0.76-1.61) and stroke (1.00; 0.54-1.85). More participants in the active treatment group were hospitalized for heart failure (1.98; 1.21-3.26; P = 0.007) and for unstable angina (1.70; 1.02-2.83; P = 0.04). Incidence of primary outcome increased with decreasing GFR. CONCLUSIONS: Active treatment with B vitamins lowered homocysteine levels in participants with CKD but did not reduce cardiovascular risk.
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