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Sökning: WFRF:(Frampton R.)

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  • 2021
  • swepub:Mat__t
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  • Glasbey, JC, et al. (författare)
  • 2021
  • swepub:Mat__t
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  • Coustenis, A., et al. (författare)
  • TandEM : Titan and Enceladus mission
  • 2009
  • Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 23:3, s. 893-946
  • Tidskriftsartikel (refereegranskat)abstract
    • TandEM was proposed as an L-class (large) mission in response to ESA's Cosmic Vision 2015-2025 Call, and accepted for further studies, with the goal of exploring Titan and Enceladus. The mission concept is to perform in situ investigations of two worlds tied together by location and properties, whose remarkable natures have been partly revealed by the ongoing Cassini-Huygens mission. These bodies still hold mysteries requiring a complete exploration using a variety of vehicles and instruments. TandEM is an ambitious mission because its targets are two of the most exciting and challenging bodies in the Solar System. It is designed to build on but exceed the scientific and technological accomplishments of the Cassini-Huygens mission, exploring Titan and Enceladus in ways that are not currently possible (full close-up and in situ coverage over long periods of time). In the current mission architecture, TandEM proposes to deliver two medium-sized spacecraft to the Saturnian system. One spacecraft would be an orbiter with a large host of instruments which would perform several Enceladus flybys and deliver penetrators to its surface before going into a dedicated orbit around Titan alone, while the other spacecraft would carry the Titan in situ investigation components, i.e. a hot-air balloon (MontgolfiSre) and possibly several landing probes to be delivered through the atmosphere.
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  • Henrion, Marc Y R, et al. (författare)
  • Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer
  • 2015
  • Ingår i: PLOS ONE. - : Public library science. - 1932-6203. ; 10:3
  • Tidskriftsartikel (refereegranskat)abstract
    • So far six susceptibility loci for renal cell carcinoma (RCC) have been discovered by genome-wide association studies (GWAS). To identify additional RCC common risk loci, we performed a meta-analysis of published GWAS (totalling 2,215 cases and 8,566 controls of Western-European background) with imputation using 1000 Genomes Project and UK10K Project data as reference panels and followed up the most significant association signals [22 single nucleotide polymorphisms (SNPs) and 3 indels in eight genomic regions] in 383 cases and 2,189 controls from The Cancer Genome Atlas (TCGA). A combined analysis identified a promising susceptibility locus mapping to 1q24.1 marked by the imputed SNP rs3845536 (Pcombined =2.30x10-8). Specifically, the signal maps to intron 4 of the ALDH9A1 gene (aldehyde dehydrogenase 9 family, member A1). We further evaluated this potential signal in 2,461 cases and 5,081 controls from the International Agency for Research on Cancer (IARC) GWAS of RCC cases and controls from multiple European regions. In contrast to earlier findings no association was shown in the IARC series (P=0.94; Pcombined =2.73x10-5). While variation at 1q24.1 represents a potential risk locus for RCC, future replication analyses are required to substantiate our observation.
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10.
  • Nilsson, Oscar, et al. (författare)
  • Growth and modulus of elasticity of pine species and hybrids three years after planting in South Africa
  • 2020
  • Ingår i: Southern Forests, a journal of forest science. - : Taylor & Francis Group. - 2070-2620 .- 2070-2639. ; 82:4, s. 367-376
  • Tidskriftsartikel (refereegranskat)abstract
    • Growth data and modulus of elasticity (MOE) of 11 different pine species and hybrids were examined at six sites in three regions in South Africa. Growth traits and three MOE variables were measured at three years of age in order to evaluate whether other potential pine species were more suitable than the current commercial species. There were strong observed species differences for all three MOE variables both within and across the four sites measured for wood properties, with across-site MOE ranging from 3.03 to 6.40 GPa. Green density varied among species, and an assumed constant green density of 1 000 kg m-3 underestimated MOE for species with a very high green density; similarly, for species with a very low green density, MOE was overestimated. Although survival was poor at several sites, the data shows that there are alternative pine species that exhibit comparable growth rates to the current commercial species. For estimating MOE, it is concluded that assuming a constant green density generally does not affect the species ranking, but if the aim is to find the 'true' MOE, sampling in the field to determine the appropriate green density is needed.
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