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- Ameller, D., et al.
(författare)
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Handling Non-functional Requirements in Model-Driven Development: An Ongoing Industrial Survey
- 2015
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Ingår i: 2015 IEEE 23rd International Requirements Engineering Conference (Re). - : IEEE. - 9781467369053
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Konferensbidrag (refereegranskat)abstract
- Model-Driven Development (MDD) is no longer a novel development paradigm. It has become mature from a research perspective and recent studies show its adoption in industry. Still, some issues remain a challenge. Among them, we are interested in the treatment of non-functional requirements (NFRs) in MDD processes. Very few MDD approaches have been reported to deal with NFRs (and they do it in a limited way). However, it is clear that NFRs need to be considered somehow in the final product of the MDD process. To better understand how NFRs are integrated into the existing MDD approaches, we have initiated the NFR4MDD project, a multi-national empirical study, based on interviews with companies working on MDD projects. Our project aims at surveying the state of the practice for this topic. In this paper, we summarize our research protocol and present the current status of our study. The discussion will focus on the peculiarities of our study's context and organization involving about 20 researchers from 8 European countries.
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- Grases-Pintó, Blanca, et al.
(författare)
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Influence of Leptin and Adiponectin Supplementation on Intraepithelial Lymphocyte and Microbiota Composition in Suckling Rats
- 2019
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Ingår i: Frontiers in Immunology. - : Frontiers Media SA. - 1664-3224. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- Dietary components in early life play a role in both microbiota and intestinal immune system maturation in mammalian species. Adipokines, as endogenously produced hormones from breast milk, may have an impact on this process. The aim of the present study was to establish the influence of leptin and adiponectin supplementation during suckling on the intraepithelial lymphocyte composition, intestinal barrier function, intestinal gene expression, and gut microbiota in rat. For this purpose, newborn Wistar rats were supplemented daily with leptin, adiponectin, or whey protein concentrate during the first 21 days of life. Lymphocyte composition was established by immunofluorescence staining and flow cytometry analysis; intestinal gene expression by real-time PCR and cecal microbiota were analyzed through 16S rRNA gene sequencing. Although leptin and adiponectin were able to increase the Tc TCRαβ+ and NKT cell proportion, they decreased the NK cell percentage in IEL. Moreover, adipokine supplementation differentially modified CD8+ IEL. While the supplementation of leptin increased the proportion of CD8αα+ IEL (associated to a more intestinal phenotype), adiponectin enhanced that of CD8αβ+ (related to a peripheral phenotype). Furthermore, both adipokines enhanced the gene expression of TNF-α, MUC-2, and MUC-3, and decreased that of FcRn. In addition, the adipokine supplementations decreased the abundance of the Proteobacteria phylum and the presence of Blautia. Moreover, leptin-supplemented animals had lower relative abundance of Sutterella and a higher proportion of Clostridium genus, among others. However, supplementation with adiponectin resulted in lower abundance of the Roseburia genus and a higher proportion of the Enterococcus genus. In conclusion, the supplementation with leptin and adiponectin throughout the suckling period had an impact on both the IEL composition and the gut microbiota pattern, suggesting a modulatory role of these adipokines on the development of intestinal functionality.
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- Oriol, M., et al.
(författare)
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FAME : Supporting continuous requirements elicitation by combining user feedback and monitoring
- 2018
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Ingår i: Proceedings - 2018 IEEE 26th International Requirements Engineering Conference, RE 2018. - : Institute of Electrical and Electronics Engineers Inc.. - 9781538674185 ; , s. 217-227
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Konferensbidrag (refereegranskat)abstract
- Context: Software evolution ensures that software systems in use stay up to date and provide value for end-users. However, it is challenging for requirements engineers to continuously elicit needs for systems used by heterogeneous end-users who are out of organisational reach. Objective: We aim at supporting continuous requirements elicitation by combining user feedback and usage monitoring. Online feedback mechanisms enable end-users to remotely communicate problems, experiences, and opinions, while monitoring provides valuable information about runtime events. It is argued that bringing both information sources together can help requirements engineers to understand end-user needs better. Method/Tool: We present FAME, a framework for the combined and simultaneous collection of feedback and monitoring data in web and mobile contexts to support continuous requirements elicitation. In addition to a detailed discussion of our technical solution, we present the first evidence that FAME can be successfully introduced in real-world contexts. Therefore, we deployed FAME in a web application of a German small and medium-sized enterprise (SME) to collect user feedback and usage data. Results/Conclusion: Our results suggest that FAME not only can be successfully used in industrial environments but that bringing feedback and monitoring data together helps the SME to improve their understanding of end-user needs, ultimately supporting continuous requirements elicitation. © 2018 IEEE.
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- Bridges, J. C., et al.
(författare)
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Petrographic classification of middle ordovician fossil meteorites from Sweden
- 2007
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Ingår i: Meteoritics and Planetary Science. - : Wiley. - 1086-9379 .- 1945-5100. ; 42:10, s. 1781-1789
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Tidskriftsartikel (refereegranskat)abstract
- The maximum diameter of chromite (FeCr2O4) grains within L chondrites reflects the petrographic type of the sample. On the basis of our measurements of nine recent L chondrites, L3 chromite D-mac = 34-50 mu m, L4 = 87-150 mu m, L5 = 76-158 mu m, and L6 = 253-638 mu m. This variation reflects the crystallization of the chromite grains during parent body thermal metamorphism.We use this calibration to classify six fossil meteorites from the Middle Ordovician in Sweden as type 3 (or 4) to 6. The high flux of L chondrites at 470 Ma contained a range of petrographic types and may have had a higher proportion of lower petrographic type meteorites than are found in recent L chondrite falls. The fossil meteorites have in places preserved recognizable chondrule textures, including porphyritic olivine, barred olivine, and radiating pyroxene. A large relict clast and fusion crust have also been tentatively identified in one fossil meteorite. Apart from chromite, all of the original meteorite minerals have been replaced by carbonate (and sheet silicate and sulfate) during diagenesis within the limestone host. The preservation of chondrule definition has allowed us to measure the mean diameters of relict chondrules. The range (0.4-0.6 mm) is consistent with measurements made in the same way on recent L chondrites.
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- Chaplin-Kramer, Rebecca, et al.
(författare)
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Ecosystem service information to benefit sustainability standards for commodity supply chains
- 2015
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Ingår i: Annals of the New York Academy of Sciences. - : Wiley. - 0077-8923 .- 1749-6632. ; 1355, s. 77-97
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Tidskriftsartikel (refereegranskat)abstract
- The growing base of information about ecosystem services generated by ecologists, economists, and other scientists could improve the implementation, monitoring, and evaluation of commodity-sourcing standards being adopted by corporations to mitigate risk in their supply chains and achieve sustainability goals. This review examines various ways that information about ecosystem services could facilitate compliance with and auditing of commodity-sourcing standards. We also identify gaps in the current state of knowledge on the ecological effectiveness of sustainability standards and demonstrate how ecosystem-service information could complement existing monitoring efforts to build credible evidence. This paper is a call to the ecosystem-service scientists to engage in this decision context and tailor the information they are generating to the needs of the standards community, which we argue would offer greater efficiency of standards implementation for producers and enhanced effectiveness for standard scheme owners and corporations, and should thus lead to more sustainable outcomes for people and nature.
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- Milone, A. P., et al.
(författare)
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The ACS survey of Galactic globular clusters XII. Photometric binaries along the main sequence
- 2012
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Ingår i: Astronomy & Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 540
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Tidskriftsartikel (refereegranskat)abstract
- Context. The fraction of binary stars is an important ingredient to interpret globular cluster dynamical evolution and their stellar population. Aims. We investigate the properties of main-sequence binaries measured in a uniform photometric sample of 59 Galactic globular clusters that were observed by HST WFC/ACS as a part of the Globular Cluster Treasury project. Methods. We measured the fraction of binaries and the distribution of mass-ratio as a function of radial location within the cluster, from the central core to beyond the half-mass radius. We studied the radial distribution of binary stars, and the distribution of stellar mass ratios. We investigated monovariate relations between the fraction of binaries and the main parameters of their host clusters. Results. We found that in nearly all the clusters, the total fraction of binaries is significantly smaller than the fraction of binaries in the field, with a few exceptions only. Binary stars are significantly more centrally concentrated than single MS stars in most of the clusters studied in this paper. The distribution of the mass ratio is generally flat (for mass-ratio parameter q > 0.5). We found a significant anti-correlation between the binary fraction in a cluster and its absolute luminosity (mass). Some, less significant correlation with the collisional parameter, the central stellar density, and the central velocity dispersion are present. There is no statistically significant relation between the binary fraction and other cluster parameters. We confirm the correlation between the binary fraction and the fraction of blue stragglers in the cluster.
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