| 1. |
- Friberg, Bertil, 1950, et al.
(författare)
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Clinical experience of TiUnite implants: a 5-year cross-sectional, retrospective follow-up study.
- 2010
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Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 12:Supplement s1
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Tidskriftsartikel (refereegranskat)abstract
- Background: Little is known of the long-term clinical and radiographic performance of moderately rough surface implants. Purpose: The aim of the present retrospective investigation was to study two pioneer cohorts of patients, that is, the first patients to receive Brånemark System® implants with a moderately rough surface (TiUnite™, Nobel Biocare AB, Göteborg, Sweden) at the present clinic. TiUnite implants were inserted either in compromised bone sites in a mixed-mouth concept together with turned implants or used solely. Patients were followed up over a period of 5 years with regard to implant survival and the marginal bone response. Materials and Methods: Patients who received both implant types (mixed group) comprised 41 subjects, and the second group (TiUnite group) comprised 70 subjects. A total of 110 turned and 68 TiUnite implants were placed in the mixed group, and 212 TiUnite implants in the TiUnite group. Follow-up radiographs were obtained at prosthesis placement and at the 1- and 5-year check-ups, and examined by independent observers. Results: One turned (0.9%) and two TiUnite (2.9%) implants failed in the mixed group, and three implants (1.6%) failed in the TiUnite group, indicating no significant differences between surfaces or groups (p < .05). The mean marginal bone loss at 5 years was 0.6 mm to 0.8 mm, also indicating no significant differences for the two implant types tested in the mixed group. Conclusions: Cumulative survival rates for the two implant surfaces were favorable at 5 years, and the marginal bone loss was low and similar for both implant surfaces.
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| 2. |
- Friberg, Bertil, 1950, et al.
(författare)
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Early failures in 4,641 consecutively placed Brånemark dental implants: a study from stage 1 surgery to the connection of completed prostheses.
- 1991
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Ingår i: The International journal of oral & maxillofacial implants. - 0882-2786. ; 6:2, s. 142-6
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Tidskriftsartikel (refereegranskat)abstract
- This study comprised 4,641 Brånemark dental implants, which were retrospectively followed from stage 1 surgery to completion of the prosthetic restorations. The implants were placed during a 3-year period (1986 to 1988) in 943 jaws, representing 889 patients with complete and partial edentulism. The jaw and sex distribution revealed a predominance of mandibles (564/943) and females (534/943). The mean age of the patients was 57.5 years (range 13 to 88 years) at implant placement. Only 69 (1.5%) fixtures failed to integrate, and most losses were seen in completely edentulous maxillae (46/69), in which the jaw bone exhibited soft quality and severe resorption. A preponderance of failures could also be seen among the shortest fixtures (7 mm). A majority of the mobile implants were recorded at the abutment connection (stage 2) operation (48/69).
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| 3. |
- Friberg, Bertil, 1950, et al.
(författare)
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Rehabilitation of edentulous mandibles by means of 5 TiUnite™ implants after one-stage surgery: A 1-year retrospective study of 90 patients
- 2008
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Ingår i: Clinical Implant Dentistry and Related Research. ; 10:1, s. 47-54
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Tidskriftsartikel (refereegranskat)abstract
- Background: Recently the present team reported the 1-year data of one-stage surgery and mainly early loading performed in edentulous mandibles using 750 turned Brånemark System R implants in 152 patients. Purpose: The aim of the present investigation was to retrospectively evaluate the 1-year results of the same treatment technique, using Brånemark System R implants with an oxidized surface (TiUnite TM). The outcome was compared with that of the former study (control) on turned implants. Materials and Methods: The present study involved 90 individuals with 450 TiUnite TM implants of mainly the Brånemark System R Mark III design, placed in edentulous mandibles and using one stage surgery. The prosthetic procedure was commenced as a mean 8 days after teh surgical intervention. Intraoral radiographs were obtained at prosthesis insertion and at the 1-year annual check-up. Failure rates of test and control groups were compared by means of the Chisquare test. Results: No implants were found to be mobile up to and including the first annual check-up, resulting in an implant cumulative survival rate (CSR) of 100%. The corresponding CSR for the control group was 97.5% and this difference in implant survival was statistically significant, when analyzed with the chi-square test (p<.001). A statistical significant difference was also demonstrated (p<.01) when conducting the same statistical analysis on the patient level. The mean marginal bone resorption during the first year of function was 0.49 mm (SD 0.56) and the corresponding figures for the control study were 0.39 mm (SD 0.46). The central TiUnite TM implant, i.e. the one placed in or in close relation to the symphyseal region showed significantly more bone loss (p<.05) than the corresponding central turned implant of the control study. Distally positioned test implants demonstrated less marginal bone loss than the corresponding central one. Conclusions: The outcome of 450 TiUnite TM implants placed in 90 patients with edentulous manidbles, of which 380 implants in 76 patients were followed for one year, showed an implant CSR of 100%. The figure was significantly different from the control study result of 97.5% on turned surface implants. The levels of marginal bone were close to identical for test and control implants at the 1-year check-up.
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| 4. |
- Friberg, Bertil, 1950, et al.
(författare)
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Rehabilitation of edentulous mandibles by means of four TiUnite implants after one-stage surgery: a 1-year retrospective study of 75 patients.
- 2010
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Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 12:Suppl 1 s1
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Tidskriftsartikel (refereegranskat)abstract
- Background: Recently, the present team reported the 1-year data of a one-stage surgery and mainly early loading with five supporting implants in completely edentulous mandibles, indicating more bone loss at the central implant, placed in the midline of the jaw. Purpose: The aim of the present retrospective investigation was to evaluate the 1-year results of the same treatment technique with four instead of five supporting implants in completely edentulous mandibles. The outcome was compared with that of a former study (control) on five implants per patient during first year of function. Materials and Methods: The present study comprised 75 patients with a total of 300 TiUnite™ implants (Nobel Biocare AB, Göteborg, Sweden) of mainly the Brånemark System ≥ Mark III design. The prosthetic procedure started and was completed on an average of 9.1 days (standard deviation [SD] 4.47) and 33.2 days (SD 16.09) after the surgical intervention, respectively. Intraoral radiographs were obtained at prosthesis insertion and at the 1-year follow-up visit. Failure rates of test and control groups were compared by means of the chi-squared test. Results: All four implants in one patient were found to be mobile at the first annual check-up, resulting in an implant cumulative survival rate (CSR) of 98.5%. The corresponding CSR for the control group was 100% (p > 0.05). The mean marginal bone resorption during the first year of function was 0.3 mm (SD 0.74) as compared with 0.5 (SD 0.56) mm for the control group (p > 0.05). Conclusions: The outcome of 300 TiUnite™ implants placed in 75 patients with edentulous mandibles, of which 268 implants in 67 patients were followed for 1 year, showed an implant CSR of 98.5%. The implant survival was not significantly different from that of the control study result of 100%, in which five instead of four supporting implants were used. The levels of marginal bone were close to identical for the corresponding test and control implants at the 1-year check-up.
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| 5. |
- Friberg, Bertil, 1950, et al.
(författare)
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Rehabilitation of Edentulous Mandibles by Means of Osseointegrated Implants: A 5-Year Follow-Up Study on One or Two-Stage Surgery, Number of Implants, Implant Surfaces, and Age at Surgery
- 2015
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Ingår i: Clinical Implant Dentistry and Related Research. - : Wiley. - 1523-0899. ; 17:3, s. 413-424
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundIn three former reports, the present team has presented the 1-year outcome of four different treatment procedures handling the edentulous mandible; that is, two-stage and one-stage surgery with turned Branemark System (R) (Nobel Biocare AB, Gothenburg, Sweden) implants (Group 1 and 2) and one-stage surgery using either 5 or 4 TiUnite (Nobel Biocare AB, Gothenburg, Sweden) implants (Group 3 and 4). PurposeThe aim of the present investigation was to follow up these patients for a period of 5 years with regard to implant/prosthesis cumulative survival rates, marginal bone loss calculations, clinical complications, and results related to age at surgery. Materials and MethodsA total of 385 patients, provided with 1,838 implants, were originally included in the four patient groups. All patients received fixed prostheses. The overall majority of patients had each five implants placed. Radiographs were obtained at prosthesis delivery, at the 1 and 5-year follow-up. ResultsA total of 1,230 implants in 259 patients (67%) were possible to follow up for 5 years. Implant Cumulative Survival Rates (CSR) in 5 years for Groups 1-4 were 99.7, 97.0, 98.5, and 98.6%. The corresponding prosthesis treatment CSR was 100, 99.3, 98.5, and 98.6%, respectively. Significantly, more patients (p<.05) lost turned implants after one-stage surgery (Group 2). Frequency distributions of implants revealed that >1.2mm bone loss was observed around 75 implants (6.4%). The moderately rough central (midline) implant showed more bone loss than other placed implants (Group 3; p<.05). The youngest half of included patients at surgery (Youngest(50%); n=193) presented significantly higher mortality than older patients as well as compared to normal population (p<.05). Patients in the Younger(50%) group showed also an association to patients with complete loss of all implants and patients with most implants with obvious bone loss after 5 years. ConclusionsAll four treatment procedures served well during the 5 years of follow-up and only eight patients (2.1%) were complete failures or showed obvious bone loss (>1.8mm) at several implants (>2 implants), mostly observed in younger patients. The few complications in relation to implant failure and/or obvious bone loss could be associated to both local impact factors (surface, implant site, surgical protocol) as well as to host response factors (systemic health).
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| 6. |
- Friberg, Bertil, 1950, et al.
(författare)
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Rehabilitation of edentulous mandibles by means of turned Brånemark System implants after one-stage surgery: a 1-year retrospective study of 152 patients.
- 2005
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Ingår i: Clinical implant dentistry and related research. - 1523-0899. ; 7:1, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Rehabilitation of the edentulous mandible with oral implants is today predominantly executed with one-stage surgery and early or immediate loading. It is generally claimed that the outcome is similar to that of the classic two-stage technique. PURPOSE: The aim of the present investigation was to retrospectively evaluate the 1-year results of one-stage surgery and early loading performed in edentulous mandibles in a large group of patients. The outcome was compared with that of a study, from the same clinic (control), that used the two-stage surgical technique in edentulous mandibles and whose data were well controlled. MATERIALS AND METHODS: The study included 152 individuals with 750 turned Brånemark System implants of various designs placed in edentulous mandibles by means of one-stage surgery. The prosthetic procedure was commenced at a mean of 13 days after the surgical intervention. Intraoral apical radiography was performed at the time of prosthesis placement and at the 1-year annual checkup. Comparison of failure rates between the test and the control groups was made by means of the chi-square test. RESULTS: A total of 18 implants in 12 patients in the study group were found to be mobile up to and including the first annual checkup, equivalent to a 1-year implant cumulative survival rate (CSR) of 97.5%. The corresponding CSR for the control group was 99.7%. Differences between the two groups in regard to implant survival reached significant levels when analyzed with the chi-square test (p < .05). No such significant difference was seen on the patient level (p > .05). Because of implant failures one prosthesis in the study group was remade. The mean marginal bone resorption during the first year of function was 0.4 mm in both groups. CONCLUSIONS: The present investigation showed a high but (compared with the classic two-stage technique) somewhat lower CSR after 1 year for the one-stage technique. More prosthetic adjustments due to implant failures were observed in the study group, and the results emphasize the need for large study samples in order to statistically verify small differences between various treatment techniques.
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| 7. |
- Friberg, Bertil, 1950, et al.
(författare)
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Soft Tissue Augmentation in Connection to Dental Implant Treatment Using a Synthetic, Porous Material - A Case Series with a 6-Month Follow-Up.
- 2012
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Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 14:6, s. 872-881
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Tidskriftsartikel (refereegranskat)abstract
- Background: Bony defects/concavities in the aesthetic zone of maxillae may interfere with the results of prosthetic procedures by producing shading superior to the crown. Such regions can be augmented either by bone or soft tissue autografts, allografts, or xenografts. Tissue shrinkage is thus anticipated, and a method to objectively measure the tissue change is valuable. Purpose: The aim of this study was to evaluate the use of a synthetic, porous material made of polyurethaneurea for buccal soft tissue augmentation in connection with implant placement in the maxillary front region. Further, to measure over time the change in buccal contour using a computerized technique. Materials and Methods: Ten patients received 12 Artelon® cylinders (5×10mm) in connection to implant placement. Preoperative and postoperative (at 3 and 6 months) study casts were obtained for computer measurements, using the preoperative reference model as a base. The volume created between the surfaces of the reference model and each of the two following superimposed models was measured in cubic millimeter. Differences in volume from pretreatment to 3 and 6 months, respectively, were compared. Results: The clinical observation during follow-up showed normal healing. The increase in mean buccal tissue volume was 50mm(3) (SD 18) after 3 months and 43mm(3) (SD 21) after 6 months, measured over a 6mm×8mm area in the maxillary front region, in comparison to before insertion of the cylinder. The reduction from 3 to 6 months was not statistically significant (p=.17). Conclusion: A synthetic, porous material for soft tissue augmentation was tested in connection to implant placement in the aesthetic zone of maxillae. The buccal contour was followed-up for 6 months using a computer volumetric technique on preoperative and postoperative study casts. Measured tissue volume showed an obvious increase during the study period. The material was biologically well received.
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| 8. |
- Friberg, Bertil, 1950, et al.
(författare)
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Turned Brånemark System R implants in wide and narrow edentulous maxillae: A retrospecitve clinical study
- 2008
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Ingår i: Clinical Implant Dentistry and Related Research. - : Wiley. - 1708-8208 .- 1523-0899. ; 10:2, s. 78-85
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Tidskriftsartikel (refereegranskat)abstract
- Background: The available jaw bone volume is regarded one most important factor when assessing the prognosis of oral implants in the rehabilitation of the edentulous maxilla. Purpose: The aim of the current investigation was to retrospectively evaluate and compare the outcome of implants placed in edentulous maxillae with either wide or narrow jaw shapes. The marginal bone loss and implant cumulative survival rates (CSRs) were calculated and analyzed with special reference to smoking habits. Materials and Methods: The study included 75 individuals with edentulous maxillae, of which 33 patients exhibited wide (Group A) and 42 patients exhibited narrow jaw shapes (Group B). A total of 506 turned Brånemark System R implants were inserted (226 in Group A and 279 in Group B) and followed clinically up to 7 years. Smoking habits were recorded. Radiographs were obtained at connection of prostheses and at the 1- and 5-year follow-up visit. The marginal bone loss was calculated for the groups and analyzed using Student's t-test. Results: Twenty-eight implants were lost during the study period, revealing implant cumulative survival rates at 7 years of 94.6% (11/226) and 93.6% (17/279) for wide and narrow crests, respectively. No difference in marginal bone loss was seen between the two groups, although a trend towards more bone loss was recorded for patients with wide crests. Smoking habits were more common in Group A (45%) than in Group B (31%). During the first year of function smokers lost significantly more marginal bone than non-smokers (p=0.0447), albeit this difference did not prevail (p>0.05) at the end of the study period. Conclusions: The implant cumulative survival rates at 7 years were equally good for the two groups of patients with various jaw shapes. Initially smokers showed significantly more marginal bone loss than non-smokers.
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| 9. |
- Hall, Jan, et al.
(författare)
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A controlled clinical exploratory study on genetic markers for peri-implantitis
- 2011
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Ingår i: EUROPEAN JOURNAL OF ORAL IMPLANTOLOGY. - 1756-2406. ; 4:4, s. 371-382
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The objective of this controlled exploratory cross-sectional study was to investigate and compare the presence of gene expression of bone resorption/remodelling in peri-implant crevicular fluid samples from healthy subjects and subjects showing obvious clinical and radiographic signs of peri-implantitis. Materials and methods: Peri-implant crevicular fluid (PICF) was sampled from seven healthy subjects and seven subjects with obvious clinical signs of peri-implantitis using paper points. The samples were analysed by quantitative polymerase chain reaction (qPCR). Biomarkers associated with bone degradation/remodelling, such as tartrate-resistant acid phosphatase (TRAP), dickkopf-related protein-1 (DKK-1), osteoprotegerin (OPG), cathepsin K (CatK) and osteocalcin (OC), were of particular interest in the study. Results: The measured levels of genetic markers were similar for the subjects in the healthy and the peri-implantitis group. Only one subject out of seven with strong and clear clinical signs of peri-implantitis exhibited a panel of genetic markers for ongoing bone degradation. This subject was also diagnosed with rheumatoid arthritis. Conclusion: The present data showed that patients with obvious clinical signs of peri-implantitis and a history of bone loss can exhibit similar gene expressions of bone loss/remodelling as clinically healthy implant patients. Absence of bone resorption markers demonstrated that it was not possible to establish ongoing bone degradation in six of seven subjects in the peri-implantitis group. The results suggest that bone resorption was not in progress at the time of PICF sampling, or that cells expressing such markers were not present in significant numbers at the site of PICF sampling.
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| 10. |
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