| 1. |
- Baliakas, Panagiotis, 1977-, et al.
(författare)
-
Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up
- 2019
-
Ingår i: HemaSphere. - : LIPPINCOTT WILLIAMS & WILKINS. - 2572-9241. ; 3:6
-
Tidskriftsartikel (refereegranskat)abstract
- Myeloid neoplasms (MNs) with germline predisposition have recently been recognized as novel entities in the latest World Health Organization (WHO) classification for MNs. Individuals with MNs due to germline predisposition exhibit increased risk for the development of MNs, mainly acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Setting the diagnosis of MN with germline predisposition is of crucial clinical significance since it may tailor therapy, dictate the selection of donor for allogeneic hematopoietic stem cell transplantation (allo-HSCT), determine the conditioning regimen, enable relevant prophylactic measures and early intervention or contribute to avoid unnecessary or even harmful medication. Finally, it allows for genetic counseling and follow-up of at-risk family members. Identification of these patients in the clinical setting is challenging, as there is no consensus due to lack of evidence regarding the criteria defining the patients who should be tested for these conditions. In addition, even in cases with a strong suspicion of a MN with germline predisposition, no standard diagnostic algorithm is available. We present the first version of the Nordic recommendations for diagnostics, surveillance and management including considerations for allo-HSCT for patients and carriers of a germline mutation predisposing to the development of MNs.
|
|
| 2. |
|
|
| 3. |
- Friis, Elisabeth, et al.
(författare)
-
Ud af naturen, ind under bregnerne
- 2018. - 1
-
Ingår i: Naturens sprog : Historier fra virkeligheden om fortryllelse - Historier fra virkeligheden om fortryllelse. - 9788741003405 ; , s. 87-96
-
Bokkapitel (refereegranskat)
|
|
| 4. |
- Kehoe, Laura, et al.
(författare)
-
Inclusion, Transparency, and Enforcement: How the EU-Mercosur Trade Agreement Fails the Sustainability Test Comment
- 2020
-
Ingår i: One Earth. - : Elsevier BV. - 2590-3322 .- 2590-3330. ; 3:3, s. 268-272
-
Tidskriftsartikel (refereegranskat)abstract
- Trade agreements could help to protect human rights, critical ecosystems, and the climate-but only if sustainability becomes a cornerstone of international trade. The EU-Mercosur trade agreement fails to meet our three tenets of sustainable trade agreements: (1) inclusion of local communities, (2) transparency mechanisms to trace commodities and provide open-access information, and (3) enforcement to legally uphold sustainability commitments.
|
|
| 5. |
- Kehoe, Laura, et al.
(författare)
-
Make EU trade with Brazil sustainable
- 2019
-
Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
|
|
| 6. |
- Liu, Jianguo, et al.
(författare)
-
Spillover systems in a telecoupled Anthropocene : typology, methods, and governance for global sustainability
- 2018
-
Ingår i: Current Opinion in Environmental Sustainability. - : Elsevier BV. - 1877-3435. ; 33, s. 58-69
-
Forskningsöversikt (refereegranskat)abstract
- The world has become increasingly telecoupled through distant flows of information, energy, people, organisms, goods, and matter. Recent advances suggest that telecouplings such as trade and species invasion often generate spillover systems with profound effects. To untangle spillover complexity, we make the first attempt to develop a typology of spillover systems based on six criteria: flows from and to sending and receiving systems, distances from sending and receiving systems, types of spillover effects, sizes of spillover systems, roles of agents in spillover systems, and the origin of spillover systems. Furthermore, we highlight a portfolio of qualitative and quantitative methods for detecting the often-overlooked spillover systems. To effectively govern spillover systems for global sustainability, we propose an overall goal (minimize negative and maximize positive spillover effects) and three general principles (fairness, responsibility, and capability).
|
|
| 7. |
- Seaquist, Jonathan, et al.
(författare)
-
Toolbox: : Operationalising Telecoupling using Network Analysis
- 2019
-
Ingår i: Telecoupling: : Exploring Land-Use Change in a Globalised World - Exploring Land-Use Change in a Globalised World. - Cham : Springer International Publishing. - 9783030111045 - 9783030111052 ; , s. 199-211
-
Bokkapitel (refereegranskat)
|
|
