| 1. |
- Chen, Daru, et al.
(författare)
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Single-longitudinal-mode erbium-doped fiber laser based on a fiber Bragg grating Fabry-Perot filter
- 2007
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Ingår i: Laser physics. - 1054-660X .- 1555-6611. ; 17:10, s. 1246-1248
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Tidskriftsartikel (refereegranskat)abstract
- A novel single-longitudinal-mode (SLM) erbium-doped fiber laser with a simple linear cavity based on a fiber Bragg grating Fabry-Perot filter (FBG-FPF) and a narrowband (similar to 0.06 nm) FBG is proposed and demonstrated experimentally. Two uniform FBGs form the FBG-FPF, which has two ultranarrow transmission bands with a bandwidth of 0.12 pm and a wavelength spacing of 0.095 nm. By slightly tuning the central wavelength of the narrowband FBG, SLM lasing at 1549.658 or 1549.563 nm (corresponding to the two transmission peaks of the FBG-FPF) is achieved with a laser output power of similar to 4 mW, when the pump power is similar to 75 mW.
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| 2. |
- Feng, Zhenhua, et al.
(författare)
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Multicore-Fiber-Enabled WSDM Optical Access Network With Centralized Carrier Delivery and RSOA-Based Adaptive Modulation
- 2015
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Ingår i: IEEE PHOTONICS JOURNAL. - : Institute of Electrical and Electronics Engineers (IEEE). - 1943-0655. ; 7:4
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Tidskriftsartikel (refereegranskat)abstract
- We proposed and experimentally demonstrated a wavelength-space division multiplexing (WSDM) optical access network architecture with centralized optical carrier delivery utilizing multicore fibers (MCFs) and adaptive modulation based on reflective semiconductor amplifier (RSOA). In our experiment, five of the outer cores are used for undirectional downstream (DS) transmission only, whereas the remaining outer core is utilized as a dedicated channel to transmit upstream (US) signals. Optical carriers for US are delivered from the optical line terminal (OLT) to the optical network unit (ONU) via the inner core and then transmitted back to the OLT after amplification and modulation by the RSOA in the colorless ONU side. The mobile backhaul (MB) service is also supported by the inner core. Wavelengths used in US transmission should be different from that of the MB in order to avoid the Rayleigh backscattering effect in bidirectional transmission. With quadrature phase-shift keying-orthogonal frequency-division multiplexing (QPSK-OFDM) modulation format, the aggregation DS capacity reaches 250 Gb/s using five outer cores and ten wavelengths, and it can be further scaled to 1 Tb/s using 20 wavelengths modulated with 16 QAM-OFDM. For US transmission, 2.5 Gb/s QPSK-OFDM transmission can be achieved just using a low-bandwidth RSOA, and adaptive modulation is applied to the RSOA to further enhance the US data rate to 3.12 Gb/s. As an emulation of high-speed MB transmission, 48 Gb/s inphase and quadrature (IQ) modulated popularization division multiplexing (PDM)-QPSK signal is transmitted in the inner core of MCF and coherently detected in the OLT side. Both DS and US optical signals exhibit acceptable performance with sufficient power budget.
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| 3. |
- Fu, Hongyan, et al.
(författare)
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A tunable single-passband microwave photonic filter with positive and negative taps using a fiber Mach-Zehnder interferometer and phase modulation
- 2010
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Ingår i: Optics and Laser Technology. - : Elsevier BV. - 0030-3992 .- 1879-2545. ; 42:1, s. 81-84
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, a tunable single-passband microwave photonic filter with positive and negative taps based on phase modulation and a fiber Mach-Zehnder interferometer (FMZI)) is presented, theoretically analyzed and experimentally demonstrated. The FMZI as the slicing filter results in a single-bandpass characteristic for the presented filter, and by using phase modulation, a number of negative taps are generated, thus making the baseband resonance suppressed, which is desirable for microwave photonic filter's application. The wavelength spacing of the FMZI can be tuned by employing an optical variable delay line, making the present filter continuously tunable. A tunable single-passband microwave photonic filter without baseband resonance is achieved in the experiment. The present filter shows an extinction ratio of up to similar to 20dB and good tuning linearity.
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| 4. |
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| 5. |
- Fu, Hongyan, et al.
(författare)
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High-Frequency Fiber Bragg Grating Sensing Interrogation System Using Sagnac-Loop-Based Microwave Photonic Filtering
- 2009
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Ingår i: IEEE Photonics Technology Letters. - : Institute of Electrical and Electronics Engineers (IEEE). - 1041-1135 .- 1941-0174. ; 21:8, s. 519-521
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Tidskriftsartikel (refereegranskat)abstract
- A novel high-frequency fiber Bragg grating (FBG) sensing interrogation system by using fiber Sagnac-loop-based microwave photonic filtering is proposed and experimentally demonstrated. By adopting the microwave photonic filtering, the wavelength shift of sensing FBG can be converted into amplitude variation of the modulated electronic radio-frequency (RF) signal. In the experiment, the strain applied onto the sensing FBG has been demodulated by measuring the intensity of the recovered RF signal, and by modulating the RF signal with different frequencies, different interrogation sensitivities can be achieved.
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| 6. |
- Fu, Hongyan, et al.
(författare)
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Transversal-Load Sensor by Using Local Pressure on a Chirped Fiber Bragg Grating
- 2010
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Ingår i: IEEE Sensors Journal. - : Institute of Electrical and Electronics Engineers (IEEE). - 1530-437X .- 1558-1748. ; 10:6, s. 1140-1141
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Tidskriftsartikel (refereegranskat)abstract
- A transversal-load sensor based on the local pressure-induced refractive index change in a chirped fiber Bragg grating (CFBG) is proposed. The local pressure induced refractive index change in the touch point can generate a main transmission peak and several subpeaks on the long wavelength side of the reflection band of the CFBG. The difference of the wavelength shifts for the main transmission peak and the first subpeak is used to measure transversal-load with temperature compensation capability.
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| 7. |
- Fu, Hongyan, et al.
(författare)
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Transversal Loading Sensor Based on Tunable Beat Frequency of a Dual-Wavelength Fiber Laser
- 2009
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Ingår i: IEEE Photonics Technology Letters. - : Institute of Electrical and Electronics Engineers (IEEE). - 1041-1135 .- 1941-0174. ; 21:14, s. 987-989
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Tidskriftsartikel (refereegranskat)abstract
- Microwave signal generation by using the photonic beating from a phase-shift fiber Bragg grating (PS-FBG)-based dual-wavelength laser is proposed and experimentally demonstrated. The dual-wavelength laser is formed by a linear cavity, in which a PS-FBG is used as a dual-wavelength selective component. Transversal loading on the PS-FBG enhances the birefringence of the optical fiber and consequently makes the transmission peak of the PS-FBG splitting into two sharp transmission peaks of orthogonal polarizations. The wavelength spacing between the two transmission peaks increases with the transversal loading on the PS-FBG, thus making the polarization beating frequency increase. This property is exploited in a transversal loading sensor.
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| 8. |
- Fu, Hongyan, et al.
(författare)
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Tunable all-optical microwave notch filter with a negative tap based on a semiconductor optical amplifier and a dispersive medium
- 2009
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Ingår i: Optics and Laser Technology. - : Elsevier BV. - 0030-3992 .- 1879-2545. ; 41:3, s. 213-216
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Tidskriftsartikel (refereegranskat)abstract
- A tunable all-optical microwave notch filter with a negative tap based on a semiconductor optical amplifier and a dispersive medium is demonstrated. A negative tap is realized through the cross gain modulation in the semiconductor optical amplifier. The free spectrum range of the notch filter can be tuned by tuning the wavelength of one of the two laser sources. The influence of the amplitude mismatch of the two lasers on the performance of the filter is analyzed. The present notch filter is easy to implement and cost-effective.
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| 9. |
- Gao, S., et al.
(författare)
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Microwave frequency up/downconversion based on dual-wavelength fibre laser
- 2009
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Ingår i: Electronics Letters. - : Institution of Engineering and Technology (IET). - 0013-5194 .- 1350-911X. ; 45:18, s. 932-933
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Tidskriftsartikel (refereegranskat)abstract
- A novel method of microwave frequency up/downconversion is proposed for microwave/millimetre-wave-based radio-over-fibre (RoF) systems. The uplink and downlink are both based on dual-wavelength single-longitudinal-mode fibre laser modulation and heterodyning, which provides the possibility to realise bidirectional RoF transmissions.
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| 10. |
- Ji, Linong, et al.
(författare)
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ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study
- 2024
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Ingår i: DIABETES THERAPY. - 1869-6953 .- 1869-6961.
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: ISIS 449884, a 2 '-O-methoxyethyl antisense oligonucleotide that targets the glucagon receptor (GCGR), has demonstrated an ability to reduce hepatic glucose output and lower the blood glucose level. The primary objective of this study was to investigate the safety and efficacy of ISIS 449884 as an add-on to metformin in a population of Chinese patients with type 2 diabetes mellitus (T2DM). Method: This was a multicenter, placebo-controlled (2:1), randomized, double-blind, parallel-enrollment, multiple-dose phase II study in Chinese patients with T2DM. A total of 90 patients who were uncontrolled by stable metformin monotherapy were randomized into three cohorts. Thirty subjects were enrolled in each cohort and received injections of ISIS 449884 (50 mg or 60 mg weekly or 100 mg every other week) or a corresponding volume of placebo (0.25 mL and 0.3 mL weekly or 0.5 mL every other week) subcutaneously in a 2:1 ratio for 16 weeks. Results: The primary efficacy endpoint was analyzed in 88 subjects (ISIS 449884, n = 59; placebo, n = 29). The corrected LS mean change from baseline in glycated hemoglobin (HbA1c) at week 17 in the pooled ISIS 449884 treatment group was - 1.31% (95% CI - 1.66%, - 0.96%), and that in the pooled placebo group was 0.15% (95% CI - 0.37%, 0.66%). The LS mean difference between the two groups was - 1.46% (95% CI - 1.92%, - 1.00%, P < 0.001). Treatment-emergent adverse events (TEAEs) occurred in 53/60 subjects (88.3%) and 25/30 subjects (83.3%) in the pooled ISIS 449884 treatment group and the pooled placebo group, respectively, with similar incidences. Drug-related TEAEs occurred in 41/60 subjects (68.3%) and 9/30 subjects (30.0%), respectively. TEAEs of grade 3 or higher occurred in 5/60 (8.3%) subjects and 2/30 (6.7%) subjects, respectively, and none of them were drug related. Conclusions: The ISIS 449884 injection add-on to metformin significantly reduced HbA1c in patients with T2DM uncontrolled by stable metformin monotherapy and showed an acceptable benefit/risk profile.
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