| 1. |
- Deiana, Federico, et al.
(författare)
-
Efficiency Assessment of Permanent Magnet Synchronous Machines for High-Speed Flywheel Energy Storage Systems
- 2016
-
Ingår i: Proceedings Of The IECON 2016 - 42Nd Annual Conference Of The IEEE Industrial Electronics Society. - : IEEE. ; , s. 4269-4274
-
Konferensbidrag (refereegranskat)abstract
- The paper presents an accurate efficiency assessment of a novel Permanent Magnet Synchronous Machine (PMSM) to be employed in a High-Speed Flywheel Energy Storage System (HS-FESS). Particularly, the proposed machine configuration aims to minimize core losses by reducing the overall amount of steel. In this regard, some of the specific design solutions adopted are introduced and briefly discussed. Much more details are given on PMSM core losses estimation, which is carried out through an extensive Finite Element Analysis (FEA) by means of JMAG. The FEA results allow the definition of a suitable lumped-parameter electrical model of the proposed PMSM, based on which a detailed PMSM efficiency assessment can be achieved. This is particularly important for identifying the most suitable PMSM operating speed range, within which the overall HS-FESS performance can be optimized.
|
|
| 2. |
- Deiana, Federico, et al.
(författare)
-
Extensive Losses Estimation of a Novel High-Speed Permanent Magnet Synchronous Machine for Flywheel Energy Storage Systems
- 2016
-
Ingår i: 2016 XXII International Conference On Electrical Machines (ICEM). - 9781509025381 ; , s. 1728-1734
-
Konferensbidrag (refereegranskat)abstract
- In this paper, the design criteria and an extensive losses analysis of a novel High-Speed Permanent Magnet Synchronous Machine (HS-PMSM) is presented. The proposed machine topology has been designed for a Flywheel Energy Storage System (FESS) with the aim of optimizing the integration between the flywheel and the HS-PMSM rotor, minimizing the overall losses at the same time. Thus, the conceptual design and sizing criteria of the FESS are introduced at first. Furthermore, a double HS-PMSM is designed, whose main specifications are presented and discussed. Subsequently, HS-PMSM standby and load losses arc determined by an extensive Finite Element Analysis (FEA) through the JMAG software package. Numerical simulations allow the identification of HS-PMSM losses over different operating conditions, confirming the effectiveness of the proposed design approach.
|
|
| 3. |
- Delogu, Giovanna Lucia, et al.
(författare)
-
A new biological prospective for the 2-phenylbenzofurans as inhibitors of α-glucosidase and of the islet amyloid polypeptide formation
- 2021
-
Ingår i: International Journal of Biological Macromolecules. - : Elsevier. - 0141-8130 .- 1879-0003. ; 169, s. 428-435
-
Tidskriftsartikel (refereegranskat)abstract
- In this study, we have investigated a series of hydroxylated 2-phenylbenzofurans compounds for their inhibitory activity against α-amylase and α-glucosidase activity.Inhibitors of carbohydrate degrading enzymes seem to have an important role as antidiabetic drugs.Diabetes mellitus is a wide-spread metabolic disease characterized by elevated levels of blood glucose. The most common is type 2 diabetes, which can lead to severe complications. Since the aggregates of islet amyloid polypeptide (IAPP) are common in diabetic patients, the effect of compounds to inhibit amyloid fibril formation was also determined.All the compounds assayed showed to be more active against α-glucosidase. Compound 16 showed the lowest IC50 value of the series, and it is found to be 167 times more active than acarbose, the reference compound. The enzymatic activity assays showed that compound 16 acts as a mixed-type inhibitor of α-glucosidase. Furthermore, compound 16 displayed effective inhibition of IAPP aggregation and it manifested no significant cytotoxicity.To predict the binding of compound 16 to IAPP and α-glucosidase protein complexes, molecular docking studies were performed.Altogether, our results support that the 2-phenylbenzofuran derivatives could represent a promising candidate for developing molecules able to modulate multiple targets involved in diabetes mellitus disorder.
|
|
