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- Ioannou, Aggelos D., et al.
(författare)
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UNILOGIC: A Novel Architecture for Highly Parallel Reconfigurable Systems
- 2020
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Ingår i: ACM Transactions on Reconfigurable Technology and Systems. - : Association for Computing Machinery (ACM). - 1936-7414 .- 1936-7406. ; 13:4
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Tidskriftsartikel (refereegranskat)abstract
- One of the main characteristics of High-performance Computing (HPC) applications is that they become increasingly performance and power demanding, pushing HPC systems to their limits. Existing HPC systems have not yet reached exascale performance mainly due to power limitations. Extrapolating from today's top HPC systems, about 100-200 MWatts would be required to sustain an exaflop-level of performance. A promising solution for tackling power limitations is the deployment of energy-efficient reconfigurable resources (in the form of Field-programmable Gate Arrays (FPGAs)) tightly integrated with conventional CPUs. However, current FPGA tools and programming environments are optimized for accelerating a single application or even task on a single FPGA device. In this work, we present UNILOGIC (Unified Logic), a novel HPC-tailored parallel architecture that efficiently incorporates FPGAs. UNILOGIC adopts the Partitioned Global Address Space (PGAS) model and extends it to include hardware accelerators, i.e., tasks implemented on the reconfigurable resources. The main advantages of UNILOGIC are that (i) the hardware accelerators can be accessed directly by any processor in the system, and (ii) the hardware accelerators can access any memory location in the system. In this way, the proposed architecture offers a unified environment where all the reconfigurable resources can be seamlessly used by any processor/operating system. The UNILOGIC architecture also provides hardware virtualization of the reconfigurable logic so that the hardware accelerators can be shared among multiple applications or tasks. The FPGA layer of the architecture is implemented by splitting its reconfigurable resources into (i) a static partition, which provides the PGAS-related communication infrastructure, and (ii) fixed-size and dynamically reconfigurable slots that can be programmed and accessed independently or combined together to support both line and coarse grain reconfiguration.(1) Finally, the UNILOGIC architecture has been evaluated on a custom prototype that consists of two 1U chassis, each of which includes eight interconnected daughter boards, called Quad-FPGA Daughter Boards (QFDBs); each QFDB supports four tightly coupled Xilinx Zynq Ultrascalei MPSoCs as well as 64 Gigabytes of DDR4 memory, and thus, the prototype features a total of 64 Zynq MPSoCs and 1 Terabyte of memory. We tuned and evaluated the UNILOGIC prototype using both low-level (baremetal) performance tests, as well as two popular real-world HPC applications, one compute-intensive and one data-intensive. Our evaluation shows that UNILOGIC offers impressive performance that ranges from being 2.5 to 400 times faster and 46 to 300 times more energy efficient compared to conventional parallel systems utilizing only high-end CPUs, while it also outperforms GPUs by a factor ranging from 3 to 6 times in terms of time to solution, and from 10 to 20 times in terms of energy to solution.
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| 2. |
- Kerry, Roger, et al.
(författare)
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A modern way to teach and practice manual therapy
- 2024
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Ingår i: Chiropractic and Manual Therapies. - : Springer Nature. - 2045-709X. ; 32:1
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Forskningsöversikt (refereegranskat)abstract
- Background: Musculoskeletal conditions are the leading contributor to global disability and health burden. Manual therapy (MT) interventions are commonly recommended in clinical guidelines and used in the management of musculoskeletal conditions. Traditional systems of manual therapy (TMT), including physiotherapy, osteopathy, chiropractic, and soft tissue therapy have been built on principles such as clinician-centred assessment, patho-anatomical reasoning, and technique specificity. These historical principles are not supported by current evidence. However, data from clinical trials support the clinical and cost effectiveness of manual therapy as an intervention for musculoskeletal conditions, when used as part of a package of care.Purpose: The purpose of this paper is to propose a modern evidence-guided framework for the teaching and practice of MT which avoids reference to and reliance on the outdated principles of TMT. This framework is based on three fundamental humanistic dimensions common in all aspects of healthcare: safety, comfort, and efficiency. These practical elements are contextualised by positive communication, a collaborative context, and person-centred care. The framework facilitates best-practice, reasoning, and communication and is exemplified here with two case studies.Methods: A literature review stimulated by a new method of teaching manual therapy, reflecting contemporary evidence, being trialled at a United Kingdom education institute. A group of experienced, internationally-based academics, clinicians, and researchers from across the spectrum of manual therapy was convened. Perspectives were elicited through reviews of contemporary literature and discussions in an iterative process. Public presentations were made to multidisciplinary groups and feedback was incorporated. Consensus was achieved through repeated discussion of relevant elements.Conclusions: Manual therapy interventions should include both passive and active, person-empowering interventions such as exercise, education, and lifestyle adaptations. These should be delivered in a contextualised healing environment with a well-developed person-practitioner therapeutic alliance. Teaching manual therapy should follow this model.
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| 3. |
- Kundakci, Burak, et al.
(författare)
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International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia
- 2022
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Ingår i: Seminars in Arthritis & Rheumatism. - : Elsevier BV. - 0049-0172 .- 1532-866X. ; 57
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To develop evidence-based expert recommendations for non-pharmacological treatments for pain, fatigue, sleep problems, and depression in fibromyalgia.Methods: An international, multidisciplinary Delphi exercise was conducted. Authors of EULAR and the Canadian Fibromyalgia Guidelines Group, members of the American Pain Society and clinicians with expertise in fibromyalgia were invited. Participants were asked to select non-pharmacological interventions that could be offered for specific fibromyalgia symptoms and to classify them as either core or adjunctive treatments. An evidence summary was provided to aid the decision making. Items receiving >70% votes were accepted, those receiving <30% votes were rejected and those obtaining 30-70% votes were recirculated for up to two additional rounds.Results: Seventeen experts participated (Europe (n = 10), North America (n = 6), and Israel (n = 1)) in the Delphi exercise and completed all three rounds. Aerobic exercise, education, sleep hygiene and cognitive behavioural therapy were recommended as core treatments for all symptoms. Mind-body exercises were recommended as core interventions for pain, fatigue and sleep problems. Mindfulness was voted core treatment for depression, and adjunctive treatment for other symptoms. Other interventions, namely music, relaxation, hot bath, and local heat were voted as adjunctive treatments, varying between symptoms.Conclusions: This study provided evidence-based expert consensus recommendations on non-pharmacological treatments for fibromyalgia that may be used to individualise treatments in clinical practice targeting the diverse symptoms associated with fibromyalgia.
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