| 1. |
- Abelev, Betty, et al.
(författare)
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Measurement of prompt J/psi and beauty hadron production cross sections at mid-rapidity in pp collisions at root s=7 TeV
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :11
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Tidskriftsartikel (refereegranskat)abstract
- The ALICE experiment at the LHC has studied J/psi production at mid-rapidity in pp collisions at root s = 7 TeV through its electron pair decay on a data sample corresponding to an integrated luminosity L-int = 5.6 nb(-1). The fraction of J/psi from the decay of long-lived beauty hadrons was determined for J/psi candidates with transverse momentum p(t) > 1,3 GeV/c and rapidity vertical bar y vertical bar < 0.9. The cross section for prompt J/psi mesons, i.e. directly produced J/psi and prompt decays of heavier charmonium states such as the psi(2S) and chi(c) resonances, is sigma(prompt J/psi) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 8.3 +/- 0.8(stat.) +/- 1.1 (syst.)(-1.4)(+1.5) (syst. pol.) mu b. The cross section for the production of b-hadrons decaying to J/psi with p(t) > 1.3 GeV/c and vertical bar y vertical bar < 0.9 is a sigma(J/psi <- hB) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 1.46 +/- 0.38 (stat.)(-0.32)(+0.26) (syst.) mu b. The results are compared to QCD model predictions. The shape of the p(t) and y distributions of b-quarks predicted by perturbative QCD model calculations are used to extrapolate the measured cross section to derive the b (b) over bar pair total cross section and d sigma/dy at mid-rapidity.
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| 2. |
- Abelev, Betty, et al.
(författare)
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Underlying Event measurements in pp collisions at root s=0.9 and 7 TeV with the ALICE experiment at the LHC
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :7
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Tidskriftsartikel (refereegranskat)abstract
- We present measurements of Underlying Event observables in pp collisions at root s = 0 : 9 and 7 TeV. The analysis is performed as a function of the highest charged-particle transverse momentum p(T),L-T in the event. Different regions are defined with respect to the azimuthal direction of the leading (highest transverse momentum) track: Toward, Transverse and Away. The Toward and Away regions collect the fragmentation products of the hardest partonic interaction. The Transverse region is expected to be most sensitive to the Underlying Event activity. The study is performed with charged particles above three different p(T) thresholds: 0.15, 0.5 and 1.0 GeV/c. In the Transverse region we observe an increase in the multiplicity of a factor 2-3 between the lower and higher collision energies, depending on the track p(T) threshold considered. Data are compared to PYTHIA 6.4, PYTHIA 8.1 and PHOJET. On average, all models considered underestimate the multiplicity and summed p(T) in the Transverse region by about 10-30%.
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| 3. |
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| 4. |
- Stanaway, Jeffrey D., et al.
(författare)
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Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017
- 2018
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Ingår i: The Lancet. - 1474-547X .- 0140-6736. ; 392:10159, s. 1923-1994
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Tidskriftsartikel (refereegranskat)abstract
- Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk-outcome pairs, and new data on risk exposure levels and risk- outcome associations. Methods We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk-outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017.
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| 5. |
- Aad, G, et al.
(författare)
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- 2015
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swepub:Mat__t
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| 6. |
- Kumar, Manish, et al.
(författare)
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MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway.
- 2015
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Ingår i: Cell host & microbe. - : elsevier. - 1934-6069 .- 1931-3128. ; 17:3, s. 345-56
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Tidskriftsartikel (refereegranskat)abstract
- The outcome of the interaction between Mycobacterium tuberculosis (Mtb) and a macrophage depends on the interplay between host defense and bacterial immune subversion mechanisms. MicroRNAs critically regulate several host defense mechanisms, but their role in the Mtb-macrophage interplay remains unclear. MicroRNA profiling of Mtb-infected macrophages revealed the downregulation of miR-let-7f in a manner dependent on the Mtb secreted effector ESAT-6. We establish that let-7f targets A20, a feedback inhibitor of the NF-κB pathway. Expression of let-7f decreases and A20 increases with progression of Mtb infection in mice. Mtb survival is attenuated in A20-deficient macrophages, and the production of TNF, IL-1β, and nitrite, which are mediators of immunity to Mtb, is correspondingly increased. Further, let-7f overexpression diminishes Mtb survival and augments the production of cytokines including TNF and IL-1β. These results uncover a role for let-7f and its target A20 in regulating immune responses to Mtb and controlling bacterial burden.
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| 7. |
- Basnet, Shyam Kumar, et al.
(författare)
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The distortion in the EU feed market due to import constraints on genetically modified soy
- 2023
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Ingår i: Agricultural and Food Economics. - 2193-7532. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- Feed importers in some EU member states face constraints on imports of genetically modified (GM) soy, a practice that may compromise the interests of EU livestock farmers. Using the cases of Sweden and Austria, we analyzed price transmission in the soy supply chain originating from Brazil, applying an asymmetric non-linear auto-regressive distributed lag (ARDL) model to identify short-run and long-run asymmetries. The results revealed significant asymmetric effects in how positive and negative price changes are absorbed within the feed industry. Notably, increases in the cost of Brazilian soy swiftly affect the prices for EU farmers, while cost reductions fail to trigger corresponding price decreases. Consequently, stronger constraints on GM soy imports are likely to exacerbate the competitiveness challenges faced by livestock farmers, primarily due to their reliance on non-GM soy. This implies that the restrictions on GM imports need to be relaxed or that low-cost local protein alternatives need to be developed.
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| 8. |
- Eriksson, Mattias, et al.
(författare)
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Environmental consequences of introducing genetically modified soy feed in Sweden
- 2018
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Ingår i: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 176, s. 46-53
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Tidskriftsartikel (refereegranskat)abstract
- Most environmental assessments of soy production and trade do not distinguish between genetically modified (GM) and non-GM soy. In reality though, soybean imports to European Union maintain identity preservation through segregated supply lines. We, therefore, perform an attributional life cycle assessment (ALCA) of the global soy chain separately for the GM and non-GM imports. First a detailed mapping of the soy-feed supply chain is done, beginning from the farm in Latin America to the animal farmer in European Union. Subsequently, life cycle is assessed to calculate the environmental impacts of each supply line for 14 impact categories, including global warming potential. Since non-GM soy based compound feed is expensive, in countries such as Sweden where there is zero tolerance for genetically modified organisms, animal farmers face a higher cost of production. As a result, there exists the possibility for a policy shift towards use of only GM soy. Hence, a consequential life cycle assessment (CLCA) is performed that includes the market effects for a scenario of shifting from GM to non-GM soy. This also ensures robustness in our estimation of the differential environmental impacts. Results from ALCA reveal that there are no significant environmental gains from importing non-GM soy over GM soy. Global warming potential and freshwater ecotoxicity are very high from non-GM imports while GM soy imports have a larger effect on land uses and terrestrial eutrophication. Increased transport distances due to segregation for non-GM soy is a major contributor to the higher negative environmental effects. Results from the CLCA, however, show that GM soy has a higher negative impact in most of the impact categories including global warming potential and freshwater and terrestrial acidification. This is possible when high demand for low cost GM triggers greater production in Latin America and substitution of locally grown protein, such as rapeseed cake, in Sweden. (C) 2017 Elsevier Ltd. All rights reserved.
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| 9. |
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| 10. |
- Eriksson, Mattias, et al.
(författare)
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Food chain sustainability in Sweden : value creation through research?
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The productivity in Swedish food sector has significantly increased during the last decades as has the capacity in distribution networks. Food company mergers combined with reductions in relative price on input resources has created a food production system that is economically more efficient. On the other hand, with some businesses growing disproportionately in comparison to others, a few big players dominate nearly the entire Swedish market. This is especially relevant in the retailing sector and raises concerns on distribution of bargaining power. This could potentially affect economic viability and innovation opportunities of smaller producers and businesses, although the direction of these effects is ambiguous. There are newer trends like private labelling, food frauds and presence of inefficient practices in the chain which need to be understood. There are also concerns such as low Swedish competitiveness, inefficient price pass through and food waste which need to be addressed. This way the sector is confronted with challenges whose interplay is unknown territory. In the face of a dynamic food sector and evolving consumer behavior, the previous successes of the Swedish food industry may have unintendedly become threats to its future sustainability. This report, therefore, scopes the need and potential for greater scientific investigation on challenges in Swedish food sector with the objective of augmenting the sustainability of the overall sector. In doing so, it describes the research front on sustainable food production from a value chain perspective with a focus on the retailer-supplier interface. The report concludes by discussing briefly some challenges and the related potential research directions. The aim is not to provide answers but to illustrate the potential of value creation through systematic analysis.
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