| 1. |
- Håkansson, H., et al.
(författare)
-
In vivo and in vitro toxicity of fractionated fish lipids, with particular regard to their content of chlorinated organic compounds
- 1991
-
Ingår i: Pharmacology and Toxicology. - : Wiley. - 0901-9928 .- 1600-0773. ; 69:6, s. 459-471
-
Tidskriftsartikel (refereegranskat)abstract
- Six different lipid matrices (the intact lipid (IL), four lipid fractions with different polarity, and the free fatty acids (FFAs) obtained by hydrolysis of the triacylglycerol (TAG) containing fraction) were obtained from salmon (Salmo salar) and eel (Anguilla anguilla), each collected at a contaminated and a comparatively uncontaminated catch site along the coast of Scandinavia. The lipid matrices were studied in toxicological test systems representing various biological functions of different organ systems from several species and trophic levels. The results were evaluated with particular respect to the concentrations of extractable organically bound chlorine (EOCl) in the matrices tested. In some test systems, the specimens with a higher EOCl concentration appeared to be more toxic. For example, the TAG containing fraction (F2) from Idefjord eel, having a higher EOCl content than F2 from Oslofjord eel, reduced the number and hatchability of eggs laid by zebrafish. Both IL and F2 of Idefjord eel increased mortality and reduced the oxygen/nitrogen-ratio in blue mussels. Non-polar compounds (F1) from Bothnian Sea salmon induced 7-ethoxyresurofin O-deethylase (EROD) activity in rainbow trout hepatocytes, whereas F1 from Senja salmon did not. F1 from Bothnian Sea salmon also reduced the number of T-cells in foetal mouse thymus anlagen in vitro compared with the cell number in anlagen exposed to F1 from Senja salmon. A positive correlation between EOCl concentration and test response was found for EROD activity in rainbow trout hepatocytes and for ATP-leakage in Erlich ascites tumour cells when testing the phospolipid containing fraction (F4). However, in most test systems the fish oils, irrespective of EOCl content, were of low toxicity, and the observed effects need to be verified in future studies.
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Garnier-Laplace, J., et al.
(författare)
-
Issues and practices in the use of effects data from FREDERICA in the ERICA Integrated Approach
- 2008
-
Ingår i: Journal of Environmental Radioactivity. - : Elsevier BV. - 0265-931X .- 1879-1700. ; 99:9, s. 1474-1483
-
Tidskriftsartikel (refereegranskat)abstract
- The ERICA Integrated Approach requires that a risk assessment screening dose rate is defined for the risk characterisation within Tiers 1 and 2. At Tier 3, no numerical screening dose rate is used, and the risk characterisation is driven by methods that can evaluate the possible effects of ionising radiation on reproduction, mortality and morbidity. Species sensitivity distribution has been used to derive the ERICA risk assessment predicted no-effect dose rate (PNEDR). The method used was based on the mathematical processing of data from FRED (FASSET radiation effects database merged with the EPIC database to form FREDERICA) and resulted in a PNEDR of 10 mu Gy/h. This rate was assumed to ascribe sufficient protection of all ecosystems from detrimental effects on structure and function under chronic exposure. The value was weighed against a number of points of comparison: (i) PNEDR values obtained by application of the safety factor method, (ii) background levels, (iii) dose rates triggering effects on radioactively contaminated sites and (iv) former guidelines from literature reviews. In Tier 3, the effects analysis must be driven by the problem formulation and is thus highly case specific. Instead of specific recommendations on numeric values, guidance on the sorts of methods that may be applied for refined effect analysis is Provided and illustrated.
|
|
| 5. |
|
|
| 6. |
- Stalmokaitė, Ignė, et al.
(författare)
-
Exploring social justice in marine spatial planning : planner and stakeholder perspectives and experiences in the Baltic Sea Region
- 2023
-
Ingår i: Journal of Environmental Planning and Management. - : Routledge. - 0964-0568 .- 1360-0559.
-
Tidskriftsartikel (refereegranskat)abstract
- This article contributes to the increasing traction of social justice in marine spatial planning (MSP) by exploring perceptions and experiences of social justice from the viewpoint of planners and different social groups who were included and (self)excluded in MSP processes. The study builds on empirical material from Poland, Latvia, and Germany consisting of interviews, MSP legislation, and documents that were analysed through the lens of a multidimensional social justice framework centring on recognition, representation, distribution, and capabilities. Results indicate that MSP institutional arrangements constrain possibilities for marginalised and less consolidated actor groups (residents, coastal tourism, and small-scale fisheries) to enjoy the same degree of recognition that is given to groups representing strategic national interests (renewable energy and shipping). We also highlight the role of planners’ self-reflectivity in enhancing/depriving capabilities of vulnerable social groups whose wellbeing and multidimensional relationships with the sea call for institutional responses adaptive to specific planning contexts.
|
|
| 7. |
|
|
