| 1. |
- Choubey, Sandhya, et al.
(författare)
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Sensitivity to neutrino decay with atmospheric neutrinos at the INO-ICAL detector
- 2018
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Ingår i: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:3
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Tidskriftsartikel (refereegranskat)abstract
- Sensitivity of the magnetized Iron Calorimeter (ICAL) detector at the proposed India-based Neutrino Observatory (INO) to invisible decay of the mass eigenstate nu(3) using atmospheric neutrinos is explored. A full three-generation analysis including Earth matter effects is performed in a framework with both decay and oscillations. The wide energy range and baselines offered by atmospheric neutrinos are shown to be excellent for constraining the nu(3) lifetime. We find that with an exposure of 500 kton - yr the ICAL atmospheric experiment could constrain the. 3 lifetime to tau(3)/m(3) > 1.51 x 10(-10) s/eV at the 90% C.L. This is 2 orders of magnitude tighter than the bound from MINOS. The effect of invisible decay on the precision measurement of theta(23) and vertical bar Delta m(32)(2)vertical bar is also studied.
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| 2. |
- Goswami, Chandan, et al.
(författare)
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Transient Receptor Potential channels : What's happening? Reflections in the wake of the 2009 TRP Meeting, Karolinska Institutet, Stockholm
- 2010
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Ingår i: Channels (Austin, Tex.). - : Informa UK Limited. - 1933-6950 .- 1933-6969. ; 4:2, s. 124-135
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Tidskriftsartikel (refereegranskat)abstract
- More than 150 participants from 25 countries gathered in Stockholm during 25(th) to 27(th) Sept 2009 to attend the meeting "TRP channels: from sensory signaling to human disease" and enjoyed an international, intensive and vibrant meeting. This meeting shed lights on the recent advances made in this field of research in different sectors of biology, and identified directions for future research and the areas where TRP channels could be used as potential targets for prevention and treatment of human diseases. The participants of this meeting shared their recent largely unpublished data, state-of-the-art techniques and their critical views which would push research in this field forward in the new decade. Another major outcome of this meeting was the realization that extensive work remains to be done to develop the necessary tools and enhance the quality of research in this area so that the prevailing controversies can be resolved. In this report we summarize the latest scientific excitements, some critical issues, as well as some future directions for research that were addressed and discussed in this meeting.
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| 3. |
- Schoville, Sean D., et al.
(författare)
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A model species for agricultural pest genomics : The genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)
- 2018
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- The Colorado potato beetle is one of the most challenging agricultural pests to manage. It has shown a spectacular ability to adapt to a variety of solanaceaeous plants and variable climates during its global invasion, and, notably, to rapidly evolve insecticide resistance. To examine evidence of rapid evolutionary change, and to understand the genetic basis of herbivory and insecticide resistance, we tested for structural and functional genomic changes relative to other arthropod species using genome sequencing, transcriptomics, and community annotation. Two factors that might facilitate rapid evolutionary change include transposable elements, which comprise at least 17% of the genome and are rapidly evolving compared to other Coleoptera, and high levels of nucleotide diversity in rapidly growing pest populations. Adaptations to plant feeding are evident in gene expansions and differential expression of digestive enzymes in gut tissues, as well as expansions of gustatory receptors for bitter tasting. Surprisingly, the suite of genes involved in insecticide resistance is similar to other beetles. Finally, duplications in the RNAi pathway might explain why Leptinotarsa decemlineata has high sensitivity to dsRNA. The L. decemlineata genome provides opportunities to investigate a broad range of phenotypes and to develop sustainable methods to control this widely successful pest.
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