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- Halldin, Sven, et al.
(författare)
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NOPEX - a northern hemisphere climate processes land surface experiment
- 1998
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Ingår i: Journal of Hydrology. - 0022-1694 .- 1879-2707. ; 212-213, s. 172-187
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Tidskriftsartikel (refereegranskat)abstract
- The interface between land surfaces and the atmosphere is a key area in climate research, where lack of basic knowledge prevents us from reducing the considerable uncertainties about predicted changes. Boreal forests play an important, but not well known, role in the global hydrological and biogeochemical cycles. NOPEX (a NOrthern hemisphere climate Processes land surface EXperiment) is devoted to the study of land surface-atmosphere interaction in a northern European forest-dominated landscape. The main NOPEX region represents the southern edge of the boreal zone. It consists of a highly heterogeneous landscape, with forests, mires, agricultural land and lakes. A second study site, in northern Finland, representing the northern edge of the boreal zone, will be introduced into NOPEX in connection with its coming winter-time field activities. Field activities, dominating the initial phase of NOPEX, are conceived to strike a balance between the need to cover multi-annual observations and the resources required to carry out measurements covering all relevant spatial scales. The long-term data collection activities, the Continuous Climate Monitoring (CCM), form the backbone of the field programme. A suite of Concentrated Field Efforts (CFEs) covering periods of summer, spring and winter brings together scientists from more then 20 countries during month-long campaigns. CFEs have been carried out in May-June 1994 and April-July 1995. A third, winter-time CFE is planned for 1998-99. The System for Information in NOPEX (SINOP) is the database which forms a backbone for modelling and analysis work, dominating the second stage of NOPEX. A series of PhD courses are run in parallell to the research activities. Analysis and modelling are done in four interacting areas, including local-scale processes, meso-scale surface-atmosphere coupling and remote sensing techniques. The fourth area, regionalization methods, aims at bringing the previous three together in order to provide improved parameterization schemes for exchange of energy, momentum, water and CO2 between land and atmosphere in hydrological and meteorological models from the meso to the global scale.
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| 5. |
- Beigi, Farideh, et al.
(författare)
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Immobilized liposome and biomembrane partitioning chromatography of drugs for prediction of drug transport
- 1998
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Ingår i: International Journal of Pharmaceutics. - 0378-5173 .- 1873-3476. ; 164:1-2, s. 129-137
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Tidskriftsartikel (refereegranskat)abstract
- Drug partitioning into lipid bilayers was studied by chromatography on liposomes and biomembranes immobilized in gel beads by freeze–thawing. The drug retention volume was expressed as a capacity factor, Ks, normalized with respect to the amount of immobilized phospholipid. Log Ks values for positively charged drugs on brain phosphatidylserine (PS)/egg phosphatidylcholine (PC) liposomes decreased as the ionic strength was increased, increased as the PS:PC ratio or the pH was increased and varied linearly with the temperature. Log Ks values for beta-blockers, phenothiazines and benzodiazepines on egg phospholipid (EPL) liposomes correlated well with corresponding values on red cell membrane lipid liposomes (r2=0.96), and on human red cell membrane vesicles containing transmembrane proteins (r2=0.96). A fair correlation was observed between the values on EPL liposomes and those on native membranes of adsorbed red cells (r2=0.86). Compared to the data obtained with liposomes, the retentions of hydrophilic drugs became larger and the range of log Ks values more narrow on the vesicles and the membranes, which expose hydrophilic protein surfaces and oligosaccharides. Lower correlations were observed between drug retention on EPL liposomes and egg PC liposomes; and between retention on liposomes (or vesicles) and immobilized artificial membrane (IAM) monolayers of PC analogues. Absorption of orally administered drugs in humans (literature data) was nearly complete for drugs of log Ks values in the interval 1.2–2.5 on vesicles. Both vesicles and liposomes can thus be used for chromatographic analysis of drug–membrane interaction and prediction of drug absorption.
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- Beldring, Stein, et al.
(författare)
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Kinematic wave approximations to hillslope hydrological processes in tills
- 2000
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Ingår i: Hydrological Processes. - 0885-6087 .- 1099-1085. ; 14:4, s. 727-745
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Tidskriftsartikel (refereegranskat)abstract
- This work has been carried out within the framework of NOPEX - a NOrthern hemisphere climate Processes land surface EXperiment. Its purpose is to describe the spatial variability of groundwater levels and soil moisture content and their influence on runoff generation in small catchments in a landscape dominated by boreal forest and till soils, which is characteristic for the Nordic countries. Kinematic wave approximations have been used to describe saturated subsurface flow and saturation overland flow in hillslopes with a thin soil layer overlying a relatively impermeable bedrock. Simultaneous analyses of catchment runoff, groundwater-table depths and soil moisture in the unsaturated zone have been performed by including the kinematic wave descriptions in a precipitation-runoff model. The results have been compared with observed hydrographs and spatial patterns of groundwater levels and soil moisture content in two small experimental catchments. Results from this study indicate that is reasonable to apply the same parameter set when describing hydrological processes in computational elements with similar characteristics at a scale of about 1 km(2) in the NOPEX area.
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- Halldin, Sven, et al.
(författare)
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Energy, water and carbon exchange in a boreal forest landscape - NOPEX experiences
- 1999
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Ingår i: Agricultural and Forest Meteorology. - 0168-1923 .- 1873-2240. ; 98-9:SI, s. 5-29
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Forskningsöversikt (refereegranskat)abstract
- The role of the land surface in controlling climate is still underestimated and access to information from the boreal-forest zone is instrumental to improve this situation. This motivated the organisation of NOPEX (Northern hemisphere climate-Processes land-surface Experiment) in the southern part of the European boreal zone. This paper summarises results from NOPEX in its first phase, dealing with spring- and summertime conditions. Two concentrated field efforts (CFE1 on 27 May-23 June 1994, CFE2 on 18 April-14 July 1995) were carried out with coordinated measurements of energy, water, and CO2 budgets at 13 ground-based sites and at various airborne platforms. Flux aggregation was a central issue in the heterogeneous, patchy NOPEX landscape. It is shown that simple land-use-weighted averaging of fluxes from fields/forests/lakes agree well with regional fluxes. Momentum fluxes can be parameterised over the whole area with a roughness length of approximately 1.5 m, whereas fluxes of sensible heat and other scalars depend on the averaging scale, Local measurements of soil moisture can be classified and meaningful averages can be deduced with a 1 km resolution. Lakes play an important role and differs in both diurnal and annual cycles compared to the forests and fields. Multiannual data from an agricultural and a forest site has allowed quantification and modelling of seldom occuring phenomena. One unexpected result was that the Norunda Common forest acted as a source and not a sink of CO2. The successful completion of CFE1-2 and a pilot winter campaign (CFE3) will lead NOPEX into its final phase, devoted to wintertime processes. Measurements and model results reside in SINOP. the System for Information in NOPEX, open for NOPEX participants. Data from CFE1 and CFE2 are released on CD as an integrated part of this Special Issue. (C) 1999 Elsevier Science B.V. All rights reserved.
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- Hudson, Lawrence N., et al.
(författare)
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The PREDICTS database : a global database of how local terrestrial biodiversity responds to human impacts
- 2014
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Ingår i: Ecology and Evolution. - : Wiley. - 2045-7758. ; 4:24, s. 4701-4735
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Tidskriftsartikel (refereegranskat)abstract
- Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species' threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that support computation of a range of biodiversity indicators, is necessary to enable better understanding of historical declines and to project - and avert - future declines. We describe and assess a new database of more than 1.6 million samples from 78 countries representing over 28,000 species, collated from existing spatial comparisons of local-scale biodiversity exposed to different intensities and types of anthropogenic pressures, from terrestrial sites around the world. The database contains measurements taken in 208 (of 814) ecoregions, 13 (of 14) biomes, 25 (of 35) biodiversity hotspots and 16 (of 17) megadiverse countries. The database contains more than 1% of the total number of all species described, and more than 1% of the described species within many taxonomic groups - including flowering plants, gymnosperms, birds, mammals, reptiles, amphibians, beetles, lepidopterans and hymenopterans. The dataset, which is still being added to, is therefore already considerably larger and more representative than those used by previous quantitative models of biodiversity trends and responses. The database is being assembled as part of the PREDICTS project (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems - ). We make site-level summary data available alongside this article. The full database will be publicly available in 2015.
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