↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Graffman K) "

Sökning: WFRF:(Graffman K)

Resultat 1-6 av 6

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Pahlman, L, et al. (författare) Improved survival with preoperative radiotherapy in resectable rectal cancer 1997 Ingår i: The New England journal of medicine. - 0028-4793. ; 336, s. 980- Tidskriftsartikel (refereegranskat)
2.	Pahlman, L, et al. (författare) Local recurrence rate in a randomised multicentre trial of preoperative radiotherapy compared with operation alone in resectable rectal carcinoma. Swedish Rectal Cancer Trial 1996 Ingår i: The European journal of surgery = Acta chirurgica. - 1102-4151. ; 162:5, s. 397-402 Tidskriftsartikel (refereegranskat)
3.	Aaltonen, K. E., et al. (författare) Gene expression of breast cancer related genes in circulating tumour cells (CTCs) from patients with metastatic breast cancer 2015 Ingår i: Annals of Oncology. - : Elsevier BV. - 0923-7534. ; 26:Suppl. 3, s. 15-15 Tidskriftsartikel (refereegranskat)abstract Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal important knowledge about the metastatic process. The aim of this pilot study was to characterize CTCs with regard to both treatment predictive and more experimental markers by analysing the expression of genes associated with breast cancer.Methods: Blood samples from twelve patients with metastatic breast cancer included in the ongoing CTC-MBC study at Lund University, Sweden (Clinical Trials Id. NCT01322893) were analysed in this pilot study. Systemic treatment included endocrine, targeted and chemotherapy regimen. Blood samples were collected before start of 1st line therapy and at four time points. If progression occurred, a new round of samples was taken. CTCs were isolated from whole blood using the commercial kits AdnaTest EMT1/stem cell and AdnaTest EMT2/stem cell (AdnaGen AG, Langenhagen, Germany). With this method, CTCs are captured using antibodies directed against EpCAM and MUC-1 (EMT1-kit) or EpCAM, HER2 and EGFR (EMT2-kit). Gene expression analyses from CTCs at each time point was performed by TATAA Biocenter (Gothenburg, Sweden) using qPCR. 38 breast cancer related genes were analysed including the oestrogen receptor (ESR), HER2, VEGFR2, ALDH1, PI3K, PTEN and TWIST1.Results: Using positive expression of pseudo-markers EpCAM, MUC1 and HER2 as definition of CTCs, 6 of 12 patients were positive for CTCs. However, gene expression of additional markers in potential CTCs suggests complex patterns such as an increase in TWIST1, ALDH1 and SATB1 at time of progression.Conclusions: We present gene expression data from CTCs isolated before and during therapy in metastatic breast cancer patients. This type of characterisation could provide information of importance for treatment response and clinical outcome.Clinical trial identification: NCT01322893, March 24 2011
4.	Andreasson, S, et al. (författare) [Prevention of alcohol problems in primary health care. Patients receptive to questions concerning alcohol and life style] 2002 Ingår i: Lakartidningen. - 0023-7205. ; 99:43, s. 4252-4255 Tidskriftsartikel (refereegranskat)
5.	Axelsson, O, et al. (författare) Färdighetsträning inom klinisk grundutbildning. Proffspatienter som utbildare. 1995 Ingår i: Läkartidningen. ; 92, s. 3456- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
6.	Brismar, B, et al. (författare) [From being a student to becoming a good physician. A model project improves the student-teacher relation] 1995 Ingår i: Lakartidningen. - 0023-7205. ; 92:24, s. 2509-10 Tidskriftsartikel (refereegranskat)

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Resultat 1-6 av 6

Avgränsa träffmängd

Typ av publikation: tidskriftsartikel (6)

Typ av innehåll: refereegranskat (5); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Graffman, K (3); Brismar, B (3); Bengtsson, NO (2); Hatschek, T (2); Johansson, C. (2); Lundell, G (2); visa fler...; LINDBERG, B (2); Glimelius, B (2); Ost, A (2); Cedermark, B (2); Svensson, C (2); Henriksson, G (2); Westman, M (2); Nilsson, S. (2); Rubio, C (2); Bergstrom, S (2); Lindstrom, C (2); Gustafsson, A (2); Magnusson, I. (2); Nilsson, E (2); Tyden, G. (2); Svensson, JO (2); Bergman, L. (2); Magnusson, O (2); Bohe, M. (2); Hugander, A (2); Ohlsson, E (2); Pahlman, L (2); Jansson, O. (2); Wilking, N (2); Forsgren, L. (2); Fagerberg, M (2); Sjodahl, R (2); EDMAN, P (2); Goldman, S (2); Dahlberg, M. (2); Hellberg, R (2); Ewerth, S (2); Dalen, J (2); Edlund, G (2); Arwidi, A (2); Robertsson, B (2); Svensson, SO (2); Fenyo, G (2); Theve, T (2); Ohman, U (2); Bark, S (2); Holmlund, D (2); Filipsson, S (2); Dafnis, G (2); visa färre...

Lärosäte: Karolinska Institutet (4); Uppsala universitet (2); Lunds universitet (1)

Språk: Engelska (6)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - Nationella bibliotekssystem
LIBRIS.kb.se

pil uppåt

Stäng

Kopiera och spara länken för att återkomma till aktuell vy