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Sökning: WFRF:(Granath Simon)

  • Resultat 1-7 av 7
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1.
  • Andreasson, Philip, et al. (författare)
  • Quantum error correction for the toric code using deep reinforcement learning
  • 2019
  • Ingår i: Quantum. - : Verein zur Forderung des Open Access Publizierens in den Quantenwissenschaften. - 2521-327X. ; 3
  • Tidskriftsartikel (refereegranskat)abstract
    • We implement a quantum error correction algorithm for bit-flip errors on the topological toric code using deep reinforcement learning. An action-value Q-function encodes the discounted value of moving a defect to a neighboring site on the square grid (the action) depending on the full set of defects on the torus (the syndrome or state). The Q-function is represented by a deep convolutional neural network. Using the translational invariance on the torus allows for viewing each defect from a central perspective which significantly simplifies the state space representation independently of the number of defect pairs. The training is done using experience replay, where data from the algorithm being played out is stored and used for mini-batch upgrade of the Q-network. We find performance which is close to, and for small error rates asymptotically equivalent to, that achieved by the Minimum Weight Perfect Matching algorithm for code distances up to d=7. Our results show that it is possible for a self-trained agent without supervision or support algorithms to find a decoding scheme that performs on par with hand-made algorithms, opening up for future machine engineered decoders for more general error models and error correcting codes.
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  • Bengtsson, Fia, 1986-, et al. (författare)
  • Environmental drivers of Sphagnum growth in peatlands across the Holarctic region
  • 2021
  • Ingår i: Journal of Ecology. - : John Wiley & Sons. - 0022-0477 .- 1365-2745. ; 109:1, s. 417-431
  • Tidskriftsartikel (refereegranskat)abstract
    • The relative importance of global versus local environmental factors for growth and thus carbon uptake of the bryophyte genusSphagnum-the main peat-former and ecosystem engineer in northern peatlands-remains unclear. We measured length growth and net primary production (NPP) of two abundantSphagnumspecies across 99 Holarctic peatlands. We tested the importance of previously proposed abiotic and biotic drivers for peatland carbon uptake (climate, N deposition, water table depth and vascular plant cover) on these two responses. Employing structural equation models (SEMs), we explored both indirect and direct effects of drivers onSphagnumgrowth. Variation in growth was large, but similar within and between peatlands. Length growth showed a stronger response to predictors than NPP. Moreover, the smaller and denserSphagnum fuscumgrowing on hummocks had weaker responses to climatic variation than the larger and looserSphagnum magellanicumgrowing in the wetter conditions. Growth decreased with increasing vascular plant cover within a site. Between sites, precipitation and temperature increased growth forS. magellanicum. The SEMs indicate that indirect effects are important. For example, vascular plant cover increased with a deeper water table, increased nitrogen deposition, precipitation and temperature. These factors also influencedSphagnumgrowth indirectly by affecting moss shoot density. Synthesis. Our results imply that in a warmer climate,S. magellanicumwill increase length growth as long as precipitation is not reduced, whileS. fuscumis more resistant to decreased precipitation, but also less able to take advantage of increased precipitation and temperature. Such species-specific sensitivity to climate may affect competitive outcomes in a changing environment, and potentially the future carbon sink function of peatlands.
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4.
  • Granath, Carl, et al. (författare)
  • Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold
  • 2020
  • Ingår i: BioResearch Open Access. - : Mary Ann Liebert. - 2164-7844 .- 2164-7860. ; 9:1, s. 269-278
  • Tidskriftsartikel (refereegranskat)abstract
    • Aortic valve stenosis is one of the most common cardiovascular diseases in western countries and can only be treated by replacement with a prosthetic valve. Tissue engineering is an emerging and promising treatment option, but in-depth knowledge about the microstructure of native heart valves is lacking, making the development of tissue-engineered heart valves challenging. Specifically, the basement membrane (BM) of heart valves remains incompletely characterized, and decellularization protocols that preserve BM components are necessary to advance the field. This study aims to characterize laminin isoforms expressed in healthy human aortic valves and establish a small animal decellularized aortic valve scaffold for future studies of the BM in tissue engineering. Laminin isoforms were assessed by immunohistochemistry with antibodies specific for individual alpha, beta, and gamma chains. The results indicated that LN-411, LN-421, LN-511, and LN-521 are expressed in human aortic valves (n = 3), forming a continuous monolayer in the endothelial BM, whereas sparsely found in the interstitium. Similar results were seen in rat aortic valves (n = 3). Retention of laminin and other BM components, concomitantly with effective removal of cells and residual DNA, was achieved through 3 h exposure to 1% sodium dodecyl sulfate and 30 min exposure to 1% Triton X-100, followed by nuclease processing in rat aortic valves (n = 3). Our results provide crucial data on the microenvironment of valvular cells relevant for research in both tissue engineering and heart valve biology. We also describe a decellularized rat aortic valve scaffold useful for mechanistic studies on the role of the BM in heart valve regeneration.
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5.
  • Granath, Gustaf, et al. (författare)
  • Environmental and taxonomic controls of carbon and oxygen stable isotope composition in Sphagnum across broad climatic and geographic ranges
  • 2018
  • Ingår i: Biogeosciences. - : Copernicus Publications. - 1726-4170 .- 1726-4189. ; 15:16, s. 5189-5202
  • Tidskriftsartikel (refereegranskat)abstract
    • Rain-fed peatlands are dominated by peat mosses (Sphagnum sp.), which for their growth depend on nutrients, water and CO2 uptake from the atmosphere. As the isotopic composition of carbon (C-12(,)13) and oxygen (O-16(,)18) of these Sphagnum mosses are affected by environmental conditions, Sphagnum tissue accumulated in peat constitutes a potential long-term archive that can be used for climate reconstruction. However, there is inadequate understanding of how isotope values are influenced by environmental conditions, which restricts their current use as environmental and palaeoenvironmental indicators. Here we tested (i) to what extent C and O isotopic variation in living tissue of Sphagnum is speciesspecific and associated with local hydrological gradients, climatic gradients (evapotranspiration, temperature, precipitation) and elevation; (ii) whether the C isotopic signature can be a proxy for net primary productivity (NPP) of Sphagnum; and (iii) to what extent Sphagnum tissue delta O-18 tracks the delta O-18 isotope signature of precipitation. In total, we analysed 337 samples from 93 sites across North America and Eurasia us ing two important peat-forming Sphagnum species (S. magellanicum, S. fuscum) common to the Holarctic realm. There were differences in delta C-13 values between species. For S. magellanicum delta C-13 decreased with increasing height above the water table (HWT, R-2 = 17 %) and was positively correlated to productivity (R-2 = 7 %). Together these two variables explained 46 % of the between-site variation in delta C-13 values. For S. fuscum, productivity was the only significant predictor of delta C-13 but had low explanatory power (total R-2 = 6 %). For delta O-18 values, approximately 90 % of the variation was found between sites. Globally modelled annual delta O-18 values in precipitation explained 69 % of the between-site variation in tissue delta O-18. S. magellanicum showed lower delta O-18 enrichment than S. fuscum (-0.83 %0 lower). Elevation and climatic variables were weak predictors of tissue delta O-18 values after controlling for delta O-18 values of the precipitation. To summarize, our study provides evidence for (a) good predictability of tissue delta O-18 values from modelled annual delta O-18 values in precipitation, and (b) the possibility of relating tissue delta C-13 values to HWT and NPP, but this appears to be species-dependent. These results suggest that isotope composition can be used on a large scale for climatic reconstructions but that such models should be species-specific.
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6.
  • Hosseini, Seyyed Hasan, et al. (författare)
  • Kombinerade X-bandsanläggningar som väderradar : Jämförelse med etablerade metoder för regnmätning
  • 2022
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • In this research report, a new methodology has been developed in order to integrate several X-band radar data sets in to one complete set. Furthermore, a direct and an indirect evaluation have been conducted compared to stationary rain gauges and C-band radar. In the indirect analysis, the input data sets were integrated into runoff models for Ellinge and Lundåkra WWTP where the results were compared to measured incoming flow to the sewage plants.
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7.
  • Piatkowski, Bryan T., et al. (författare)
  • Draft Metagenome Sequences of the Sphagnum (Peat Moss) Microbiome from Ambient and Warmed Environments across Europe
  • 2022
  • Ingår i: Microbiology Resource Announcements. - : American Society for Microbiology. - 2576-098X. ; 11:10
  • Tidskriftsartikel (refereegranskat)abstract
    • We present 49 metagenome assemblies of the microbiome associated with Sphagnum (peat moss) collected from ambient, artificially warmed, and geothermally warmed conditions across Europe. These data will enable further research regarding the impact of climate change on plant-microbe symbiosis, ecology, and ecosystem functioning of northern peatland ecosystems.
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