| 1. |
|
|
| 2. |
|
|
| 3. |
- Brännström, Jonas, et al.
(författare)
-
Clinical application of long-term intensity and pitch matches in fluctuating low-frequency hearing loss.
- 2008
-
Ingår i: International Journal of Audiology. - : Informa UK Limited. - 1708-8186 .- 1499-2027. ; 47:7, s. 412-419
-
Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study was to measure changes in intensity and pitch matches to better assess disease activity in fluctuating hearing loss. Long-term suprathreshold audiometry was carried out at home on a subject with a unilateral fluctuating low-frequency hearing loss during a period when the subject demonstrated no symptoms and a period when the subject reported hearing loss, aural pressure, and tinnitus. Daily measurements of binaural intensity and pitch matches were made. Day-to-day fluctuations were clearly accentuated during the period when the subject experienced symptoms. Specifically, deviations from the reference tone were only observed for binaural pitch matches at 1 kHz during the period without symptoms; however, highly fluctuating binaural intensity and pitch matches were observed at 0.25 kHz during the period with symptoms. These fluctuations were not observed in a normal-hearing group. The results suggest that long-term measurements of binaural intensity and pitch matches can be used to monitor disease activity in fluctuating low-frequency hearing loss.
|
|
| 4. |
- Brännström, Jonas, et al.
(författare)
-
Effects on cochlear frequency selectivity after hypobaric pressure exposure.
- 2008
-
Ingår i: The Journal of the Acoustical Society of America. - : Acoustical Society of America (ASA). - 1520-8524 .- 0001-4966. ; 123:5
-
Tidskriftsartikel (refereegranskat)abstract
- The effects of hypobaric pressure chamber exposure was measured in noise in ten patients with monaural fluctuating low-frequency hearing loss (FLFHL) such as Meniere's disease using psychophysical tuning curves (PTC), transiently evoked otoacoustic emissions (TEOAE), binaural pitch matches and speech recognition scores (SRS) in noise. In the literature, reversible hearing losses have been observed in about 50 % of the patients, but sometimes improved SRS can be observed in patients without hearing threshold improvement. This indicates possible effects of pressure treatment on cochlear frequency selectivity. The relative overpressure in the middle ear obtained after repeated exposures in hypobaric pressure chamber (total duration 18.5 to 28 minutes) was used to impose pressure gradients to the inner ear. The results indicated that the treatment effects were small, but slightly improved SRS in noise, TEOAEs emission strength and PTCs were observed after treatment. Pure tone hearing thresholds improved only for patients exposed to longer treatment durations. Subjective improvement at follow-up could not be predicted from the results. Although the effects were small, the data suggest that hypobaric pressure treatment may improve cochlear frequency selectivity in the affected ear in patients with monaural FLFHL.
|
|
| 5. |
- Brännström, Jonas, et al.
(författare)
-
Long-term measurement of binaural intensity and pitch matches. II. Fluctuating low-frequency hearing loss.
- 2008
-
Ingår i: International Journal of Audiology. - : Informa UK Limited. - 1708-8186 .- 1499-2027. ; 47:11, s. 675-687
-
Tidskriftsartikel (refereegranskat)abstract
- Thirteen subjects made consecutive long-term recordings of binaural intensity and pitch matches in their homes using portable equipment to assess hearing fluctuations. Two groups of subjects were used; one with monaural fluctuating low-frequency hearing loss (FLFHL) without vertigo, and one with monaural Meniere's disease (i.e. FLFHL with vertigo). The subjects measured binaural pitch matches using a 0.25- or 1-kHz reference tone presented at 60 dB SPL to one ear, and a loudness-matched test tone of adjustable frequency presented to the other ear during one to several weeks. Their results were compared to those previously obtained from ten normal-hearing subjects. Both groups of subjects showed fluctuations in binaural intensity and pitch matches not seen in the normal-hearing group. We calculated the average day-to-day difference in matched intensity and frequency for each subject's test period as a measure of disease activity. This measure indicated that the group with Meniere's disease has a higher disease activity than the group with FLFHL without vertigo, and that both these groups of subjects had higher disease activity than normal-hearing subjects.
|
|
| 6. |
- Brännström, Jonas, et al.
(författare)
-
Long-term measurement of binaural intensity matches and pitch matches. I. Normal hearing.
- 2008
-
Ingår i: International Journal of Audiology. - : Informa UK Limited. - 1708-8186 .- 1499-2027. ; 47:2, s. 59-66
-
Tidskriftsartikel (refereegranskat)abstract
- Changes in pitch perception and hearing thresholds over time have been observed in subjects with monaural fluctuating low-frequency hearing loss and Ménière's disease. Long-term suprathreshold audiometry and binaural pitch matches could provide information of these changes. Ten normal subjects were tested for stability of binaural intensity and pitch matches during 9-22 days in their homes with newly developed portable test equipment. Binaural pitch matches were measured using a 0.25- or 1-kHz reference tone presented at 60 dB SPL to one ear, and a loudness-matched test tone of adjustable frequency presented to the other ear. The results showed stable binaural intensity matches (individual inter-quartile ranges, IQRs, 1.2 to 5.7 dB), but binaural pitch matches varied greatly (IQR -0.6 to 5.3% at 0.25 kHz; IQR -1.6 to 7.9% at 1 kHz). Binaural pitch-matching was much better in subjects who could define pitch precisely during monaural pitch matching. It was concluded that in future long-term evaluations of patients with fluctuating inner-ear function, binaural intensity matches could be suitable for all, but binaural pitch matching only for selected patients.
|
|
| 7. |
|
|
| 8. |
- Brännström, K J, et al.
(författare)
-
Hypobaric pressure exposure effects on cochlear frequency selectivity in fluctuating, low-frequency hearing loss.
- 2009
-
Ingår i: Journal of Laryngology and Otology. - 1748-5460. ; 123, s. 710-717
-
Tidskriftsartikel (refereegranskat)abstract
- Aim:To study the effects of hypobaric pressure chamber exposure on the cochlear frequency selectivity of subjects with monaural, fluctuating, low-frequency hearing loss, such as occurs in Ménière's disease.Methods:We used a hypobaric pressure chamber to create relative underpressure in the ear canal, in order to impose positive pressure gradients on the inner ear. Psychophysical tuning curves, transiently evoked otoacoustic emissions and speech recognition scores in noise were measured in 10 subjects with fluctuating, low-frequency hearing loss, before and after pressure exposure.Results:After the exposure, subjects' overall pure tone averages showed no improvement, but individual results showed improved speech recognition scores in noise (six subjects), increased transiently evoked otoacoustic emission strength (three subjects) and increased psychophysical tuning curve steepness (two subjects). Deteriorations were also seen, mainly in psychophysical tuning curves. No association could be established between the different tests, and the measured parameters could not predict subjective improvement.Conclusion:The results suggest variable effects of hypobaric pressure exposure on inner-ear physiology.
|
|
| 9. |
- Einarsson, Einar-Jon, et al.
(författare)
-
Long term hearing degeneration after platinum-based chemotherapy in childhood.
- 2010
-
Ingår i: International Journal of Audiology. - : Informa UK Limited. - 1708-8186 .- 1499-2027. ; 49:10, s. 765-771
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to investigate long-term development of hearing in subjects who had received platinum-based chemotherapy in childhood or adolescence. Another aim was to assess the self-reported hearing loss handicap and compare it to audiometric measurements. Medical records from individuals diagnosed with childhood cancer and treated with platinum-based chemotherapy between 1985 and 2000 at the University Hospital in Lund Sweden were reviewed retrospectively. Fifteen subjects, who fulfilled the eligibility criteria set for the study, underwent a thorough audiometric evaluation. The results show that the hearing loss, in subjects with ototoxicity had increased after the end of treatment, to include also the lower frequencies. The largest deterioration in hearing thresholds, up to 55 dB HL, was found at frequencies above 2 kHz. The findings also reveal that the subjects have a considerably greater hearing loss handicap and disability than would be expected from the results of the audiometric evaluations. The conclusion of this study is that children and adolescence treated with platinum-based chemotherapy should have regular audiometric follow-up examinations, also many years after the end of treatment. Furthermore, assessments of self-reported hearing disability should be made during and after chemotherapy.
|
|
| 10. |
- Engervall, K, et al.
(författare)
-
Borreliosis as a cause of peripheral facial palsy: a multi-center study
- 1995
-
Ingår i: ORL. - 0301-1569. ; 57:4, s. 202-206
-
Tidskriftsartikel (refereegranskat)abstract
- Borreliosis is known to be a common cause of peripheral facial palsy in Stockholm and its vicinity. The aim of the present study was to investigate the frequency and characteristics of borreliosis among patients with peripheral facial palsy in different parts of Sweden. All serological tests were performed in one laboratory. Ten Swedish Ear Nose and Throat clinics participated in a prospective 1-year study of patients seeking medical attention for acute peripheral facial palsy. Twenty-eight (6%) out of totally 446 patients fulfilled the criteria for the diagnosis of borreliosis. The frequency varied between 1 and 16% and was highest along the southeast coast of Sweden whereas no case was reported from the northern part of the country. Borreliosis was more common among children with facial palsy than among adults. The infection occurred during all seasons although it appears to be less frequent during the spring months. Only a minority of the borrelial patients had a history of a preceding tick bite or erythema migrans. The fairly low overall frequency of this secondary stage of borreliosis in the study may be a result of better knowledge of the disease and earlier treatment of its early manifestations. In Sweden's endemic areas borreliosis is a common cause of peripheral facial palsy, and therefore all patients with facial palsy in these regions should be examined for borrelial infection.
|
|
