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Sökning: WFRF:(Grigorieva E)

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1.
  • Abdesselam, A., et al. (författare)
  • The ATLAS semiconductor tracker end-cap module
  • 2007
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 575:3, s. 353-389
  • Tidskriftsartikel (refereegranskat)abstract
    • The challenges for the tracking detector systems at the LHC are unprecedented in terms of the number of channels, the required read-out speed and the expected radiation levels. The ATLAS Semiconductor Tracker. (SCT) end-caps have a total of about 3 million electronics channels each reading out every 25 ns into its own on-chip 3.3 mu s buffer. The highest anticipated dose after 10 years operation is 1.4x10(14) cm(-2) in units of 1 MeV neutron equivalent (assuming the damage factors scale with the non-ionising energy loss). The forward tracker has 1976 double-sided modules, mostly of area similar to 70 cm(2), each having 2 x 768 strips read out by six ASICs per side. The requirement to achieve an average perpendicular radiation length of 1.5% X-0, while coping with up to 7 W dissipation per module (after irradiation), leads to stringent constraints on the thermal design. The additional requirement of 1500e(-) equivalent noise charge (ENC) rising to only 1800e(-) ENC after irradiation, provides stringent design constraints on both the high-density Cu/Polyimide flex read-out circuit and the ABCD3TA read-out ASICs. Finally, the accuracy of module assembly must not compromise the 16 mu m (r phi) resolution perpendicular to the strip directions or 580 mu m radial resolution coming from the 40 mrad front-back stereo angle. A total of 2210 modules were built to the tight tolerances and specifications required for the SCT. This was 234 more than the 1976 required and represents a yield of 93%. The component flow was at times tight, but the module production rate of 40-50 per week was maintained despite this. The distributed production was not found to be a major logistical problem and it allowed additional flexibility to take advantage of where the effort was available, including any spare capacity, for building the end-cap modules. The collaboration that produced the ATLAS SCT end-cap modules kept in close contact at all times so that the effects of shortages or stoppages at different sites could be rapidly resolved.
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  • Evgenieva, Tsvetina, et al. (författare)
  • Three-point observation in the troposphere over Sofia-Plana Mountain,Bulgaria
  • 2011
  • Ingår i: International Journal of Remote Sensing. - : Informa UK Limited. - 0143-1161 .- 1366-5901. ; 32:24, s. 9343-9363
  • Tidskriftsartikel (refereegranskat)abstract
    • Based on a novel combination of approaches and instruments, this article presents campaign-based results from atmospheric boundary layer (ABL) height and aerosol optical depth (AOD) measurements carried out at two different experimental sites in Sofia, as well as from three-point measurements of aerosol number concentrations. Several instruments (lidar (developed by the IE), ceilometer, aerosol particle counter, sun photometer and meteorological sensors) were used in this study. Based on joint interpretation of the instruments' data we assess the influence of the atmospheric aerosol in the planetary boundary layer and the significant influence of aerosol layers and high clouds on AOD values. Measurements of AOD in the city basin gave values in the range 0.22-0.41 for cloud-free skies, and up to around 0.8 under partly cloudy conditions. The information obtained during the two campaigns indicates that aerosol particle concentrations were lower in park areas than along heavy-traffic thoroughfares in the city, but higher than in the mountain area. In conclusion, our study demonstrates the potential of employing a broad array of instruments for the study of boundary layer and aerosol over large, valley-situated and heavily urbanized city areas.
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  • Foster, Katie E, et al. (författare)
  • EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.
  • 2010
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 107:30
  • Tidskriftsartikel (refereegranskat)abstract
    • Thymus organogenesis requires coordinated interactions of multiple cell types, including neural crest (NC) cells, to orchestrate the formation, separation, and subsequent migration of the developing thymus from the third pharyngeal pouch to the thoracic cavity. The molecular mechanisms driving these processes are unclear; however, NC-derived mesenchyme has been shown to play an important role. Here, we show that, in the absence of ephrin-B2 expression on thymic NC-derived mesenchyme, the thymus remains in the cervical area instead of migrating into the thoracic cavity. Analysis of individual NC-derived thymic mesenchymal cells shows that, in the absence of ephrin-B2, their motility is impaired as a result of defective EphB receptor signaling. This implies a NC-derived cell-specific role of EphB-ephrin-B2 interactions in the collective migration of the thymic rudiment during organogenesis.
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  • Resultat 1-10 av 11

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