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Search: WFRF:(Gron Christian)

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  • Gron, Christian, et al. (author)
  • Kloroform i vand fra skove
  • 2005
  • In: FSL Skovbrugsserien. - 0907-0346. ; 34, s. 77-86
  • Journal article (other academic/artistic)
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  • Laturnus, Frank, et al. (author)
  • Organic waste products in agriculture - Monitoring the waste constituents phthalate esters in soil-crop system by gas chromatography and ion trap tandem mass spectrometry
  • 2007
  • In: JOURNAL OF ENVIRONMENTAL ENGINEERING AND LANDSCAPE MANAGEMENT. - 1648-6897. ; 15:4, s. 253-260
  • Journal article (peer-reviewed)abstract
    • A method is described for monitoring phthalate esters in organic waste products, agricultural soil and crops. Solvent extraction, Ultra Turrax homogenisation and sonification were used to isolate the compounds from the sample matrices. Solid phase extraction was applied for purification, and gas chromatography with tandem mass spectrometry for identification. With the method, six phthalate esters were determined in different matrices. The detection limits were in the range of 1 to 10 mu g kg(-1) wet weight, except for DEHP, which had a detection limit approaching 100 mu g kg(-1) wet weight. Repeatabilities were from 5 to 20% relative standard deviation. Recoveries were from 6 to 100%, depending on the compound analysed. However, except for the polar phthalates DMP and DEP, the recoveries were above 70%. The method feasibility was demonstrated in an investigation of the occurrence of phthalate esters in barley, rape, carrots, agricultural soil, aerobic and anaerobic sludge, household compost and pig manure.
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5.
  • Verder, Henrik, et al. (author)
  • Early Surfactant Guided by Lamellar Body Counts on Gastric Aspirate in Very Preterm Infants
  • 2013
  • In: Neonatology. - : S. Karger AG. - 1661-7800 .- 1661-7819. ; 104:2, s. 116-122
  • Journal article (peer-reviewed)abstract
    • Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation and supported with nasal continuous positive airway pressure (nCPAP) to receive surfactant guided either by LBC (intervention group) or increasing need for oxygen (control group). The primary outcome was mechanical ventilation or death within 5 days. Secondary outcomes included need for oxygen expressed by arterial to alveolar oxygen tension ratio (a/APO(2)) at the age of 6 h and need for oxygen at day 28. Results: The primary outcomes were equal (25%) in the two groups. The intervention group had higher a/APO(2) than the control group at 6 h, median 0.64 versus 0.52 (p < 0.01), and the subgroup with gestational age 26-29 weeks needed fewer days of oxygen supplementation than the controls, median 2 vs. 9 days (p = 0.01), and fewer infants needed oxygen at day 28 (p = 0.04). Furthermore, there was a tendency in the intervention group towards a shorter duration of nCPAP. Too little or viscose aspirate in 23% of the cases was a limitation of the method. Conclusion: Using LBC test as indicator of lung maturity and early surfactant therapy in very preterm newborns, it is possible to reduce the need for oxygen supplementation. Copyright (C) 2013 S. Karger AG, Basel
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