| 1. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 2. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 3. |
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| 4. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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| 5. |
- Birdsong, Björn K., et al.
(författare)
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Large-scale synthesis of 2D-silica (SiOx) nanosheets using graphene oxide (GO) as a template material
- 2023
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Ingår i: Nanoscale. - : Royal Society of Chemistry (RSC). - 2040-3364 .- 2040-3372. ; 15:31, s. 13037-13048
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Tidskriftsartikel (refereegranskat)abstract
- Graphene oxide (GO) was used in this study as a template to successfully synthesize silicon oxide (SiOx) based 2D-nanomaterials, adapting the same morphological features as the GO sheets. By performing a controlled condensation reaction using low concentrations of GO (<0.5 wt%), the study shows how to obtain 2D-nanoflakes, consisting of GO-flakes coated with a silica precursor that were ca. 500 nm in lateral diameter and ca. 1.5 nm in thickness. XPS revealed that the silanes had linked covalently with the GO sheets at the expense of the oxygen groups present on the GO surface. The GO template was shown to be fully removable through thermal treatment without affecting the nanoflake morphology of the pure SiOx-material, providing a methodology for large-scale preparation of SiOx-based 2D nanosheets with nearly identical dimensions as the GO template. The formation of SiOx sheets using a GO template was investigated for two different silane precursors, (3-aminopropyl) triethoxysilane (APTES) and tetraethyl orthosilicate (TEOS), showing that both precursors were capable of accurately templating the graphene oxide template. Molecular modeling revealed that the choice of silane affected the number of layers coated on the GO sheets. Furthermore, rheological measurements showed that the relative viscosity was significantly affected by the specific surface area of the synthesized particles. The protocol used showed the ability to synthesize these types of nanoparticles using a common aqueous alcohol solvent, and yield larger amounts (∼1 g) of SiOx-sheets than what has been previously reported.
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| 6. |
- Capezza, Antonio Jose, et al.
(författare)
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Biodegradable Fiber-Reinforced Gluten Biocomposites for Replacement of Fossil-Based Plastics
- 2023
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Ingår i: ACS Omega. - : American Chemical Society (ACS). - 2470-1343. ; 9:1, s. 1341-1351
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Tidskriftsartikel (refereegranskat)abstract
- Biocomposites based on wheat gluten and reinforced with carbon fibers were produced in line with the strive to replace fossil-based plastics with microplastic-free alternatives with competing mechanical properties. The materials were first extruded/compounded and then successfully injection molded, making the setup adequate for the current industrial processing of composite plastics. Furthermore, the materials were manufactured at very low extrusion and injection temperatures (70 and 140 degrees C, respectively), saving energy compared to the compounding of commodity plastics. The sole addition of 10 vol % fibers increased yield strength and stiffness by a factor of 2-4 with good adhesion to the protein. The biocomposites were also shown to be biodegradable, lixiviating into innocuous molecules for nature, which is the next step in the development of sustainable bioplastics. The results show that an industrial protein coproduct reinforced with strong fibers can be processed using common plastic processing techniques. The enhanced mechanical performance of the reinforced protein-based matrix herein also contributes to research addressing the production of safe materials with properties matching those of traditional fossil-based plastics.
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| 7. |
- Capezza, Antonio Jose
(författare)
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Sustainable Biobased Protein Superabsorbents from Agricultural Co-Products
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The preparation of sustainable protein superabsorbents from agricultural industry side-streams is reported. Wheat gluten (WG), a co-product from the ethanol/starch industry, was processed into foams with sponge-like behavior and high liquid uptake. The materials were obtained by phase-separation of aqueous WG dispersions followed by ambient drying, or by lyophilization. The use of a natural and non-toxic cross-linker (genipin) resulted in foams with high water swelling properties (~18 g/g in 10 min). The rapid swelling may be of use in bio-based foams in e.g., sanitary pads.As an alternative, potato protein concentrate (PPC, side-stream from the starch industry), was functionalized and prepared as particles. The liquid swelling capacity was compared after acylation with five different agents. It is shown that the PPC can be acylated to replicate the chemistry of synthetic superabsorbent polymers (SAP), showing water swelling capacity >10 g/g. The acylation (using EDTAD) of WG suspensions resulted in protein particles with water and saline uptake of 22 and 5 g/g, respectively. Limited network stability was however observed when acylating WG in low-protein suspensions. This was addressed by mixing the acylated protein with genipin, which provided a stable protein network. The process gave functionalized particles with swelling capacity ~40 g/g and ~80 % retention of swelling in centrifuge retention tests.The extrusion of WG showed that porous WG with water uptake of 500 % can be produced. Further, the scalability of PPC production was pilot-tested by functionalizing potato fruit juice (PFJ), containing the potato protein in its soluble state before the industrial drying used to obtain PPC. This resulted in water swelling capacities >10 g/g, which was comparable to the PPC-functionalized materials. The results pave the way for future optimization of high-throughput production techniques using protein sources in mass production of sustainable protein-based SAPs.
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| 8. |
- Danaei, Goodarz, et al.
(författare)
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Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants
- 2015
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Ingår i: The Lancet Diabetes & Endocrinology. - 2213-8595 .- 2213-8587. ; 3:8, s. 624-637
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Tidskriftsartikel (refereegranskat)abstract
- Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in different regions. Methods We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defining diabetes. Diabetes was defined using HbA(1c) (HbA(1c) >= 6 . 5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT definitions (FPG >= 7 . 0 mmol/L or 2hOGTT >= 11 . 1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using different definitions graphically and by regression analyses. We calculated sensitivity and specificity of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specificity in each survey, and then pooled results using a random-effects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori. Findings Population prevalence of diabetes based on FPG- or-2hOGTT was correlated with prevalence based on FPG alone (r= 0 . 98), but was higher by 2-6 percentage points at different prevalence levels. Prevalence based on HbA(1c) was lower than prevalence based on FPG in 42 . 8% of age-sex-survey groups and higher in another 41 . 6%; in the other 15 . 6%, the two definitions provided similar prevalence estimates. The variation across studies in the relation between glucose-based and HbA(1c)-based prevalences was partly related to participants' age, followed by natural logarithm of per person gross domestic product, the year of survey, mean BMI, and whether the survey population was national, subnational, or from specific communities. Diabetes defined as HbA(1c) 6 . 5% or more had a pooled sensitivity of 52 . 8% (95% CI 51 . 3-54 . 3%) and a pooled specificity of 99 . 74% (99 . 71-99 . 78%) compared with FPG 7 . 0 mmol/L or more for diagnosing previously undiagnosed participants; sensitivity compared with diabetes defined based on FPG-or-2hOGTT was 30 . 5% (28 . 7-32 . 3%). None of the preselected study-level characteristics explained the heterogeneity in the sensitivity of HbA(1c) versus FPG. Interpretation Different biomarkers and definitions for diabetes can provide different estimates of population prevalence of diabetes, and differentially identify people without previous diagnosis as having diabetes. Using an HbA(1c)-based definition alone in health surveys will not identify a substantial proportion of previously undiagnosed people who would be considered as having diabetes using a glucose-based test.
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| 9. |
- Perez-Puyana, Victor M., et al.
(författare)
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Functionalization Routes for Keratin from Poultry Industry Side-Streams-Towards Bio-Based Absorbent Polymers
- 2023
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Ingår i: Polymers. - : MDPI AG. - 2073-4360. ; 15:2, s. 351-
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Tidskriftsartikel (refereegranskat)abstract
- Keratin is a largely available protein that can be obtained from the ca. 3 million tons of feathers that the European poultry industry produces as a side-stream. Here, the functionalization of keratin from poultry feathers was evaluated using a one- versus two-stage process using two functionalization agents (succinic anhydride-SA and ethylene dianhydride-EDTAD). The functionalization resulted in the keratin having improved liquid swelling capacities, reaching up to 400%, 300%, and 85% increase in water, saline, and blood, respectively, compared to non-functionalized keratin. The highest swelling was obtained for samples functionalized with EDTAD (one-stage process), while the highest saline uptake was noted for samples processed with 25 wt% SA (two-stage process). Swelling kinetics modeling indicated that the water uptake by the functionalized samples takes place in two steps, and the EDTAD samples showed the highest diffusivity. It is demonstrated that the one-stage functionalization of keratin utilizing EDTAD results in better performance than two-stages, which allows for resource-saving and, thereby, protecting the environment. The results show some potential for the keratin to be utilized as liquid absorbent materials in water, saline, and blood uptake applications. Using keratin from side-streams is an advantage from a sustainability perspective over biomacromolecules that need to be extracted from virgin biomass.
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