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- 2019
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Gusev, Alexey, et al.
(författare)
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Structure-induced luminescence and bioactivities of Zinc(II) complexes with 2-(2,4-dichlorophenoxy)-N?-[pyridin-2-ylmethylene]acetohydrazide
- 2023
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Ingår i: Inorganica Chimica Acta. - : ELSEVIER SCIENCE SA. - 0020-1693 .- 1873-3255. ; 551
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Tidskriftsartikel (refereegranskat)abstract
- The structure and photophysical properties of the series of Zn(II) complex with the hydrazone ligand, 2-(2,4dichlorophenoxy)-N -[1-pyridin-2-ylmethylene]acetohydrazide, and different counter anions have been synthesized and characterized by single crystal X-ray diffraction, FT-IR, elemental analyses and ESI-MS. X-ray crystallography has proved the neutral or monoanionic form of ligand upon coordination. All complexes are mononuclear with the tetra/penta/hexacoordinated zinc atoms. The diverse supramolecular architectures of the complexes show that counter-anions have significant impacts on the structures. Furthermore DFT, luminescence properties, antibacterial and herbicide activities of the complexes have been investigated were carried out as well.
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| 3. |
- Gusev, V.A., et al.
(författare)
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Intensification of the impact of high-intensity focused ultrasound (HIFU) with special spatiotemporal modulation
- 2013
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Ingår i: Acoustical Physics. - : Springer. - 1063-7710 .- 1562-6865. ; 59:1, s. 45-50
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Tidskriftsartikel (refereegranskat)abstract
- The principle of forming a special form of powerful acoustic signals is proposed, which makes it possible to ensure precise spatiotemporal beam focusing. The introduction of a transverse-coordinate-dependent local wave frequency is suggested, due to which the equality of the formation lengths of a discontinuity for all rays is achieved. This thereby ensures an increase in nonlinear absorption; as a result, the temperature and radiation action of focused ultrasound on the medium increase.
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| 4. |
- Gusev, V. A., et al.
(författare)
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Nonlinear sound in a gas-saturated sediment layer
- 2015
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Ingår i: Acoustical Physics. - : Maik Nauka/Interperiodica. - 1063-7710 .- 1562-6865. ; 61:2, s. 152-164
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Tidskriftsartikel (refereegranskat)abstract
- Wave propagation in a near-bottom layer containing gas bubbles is analyzed. Evolution equations are derived for intense acoustic waves and wave beams in a medium with an inhomogeneous bubble distribution. The field of an intense beam along the axis of the focusing sound channel is calculated. The coefficients of reflection and passage of sound from a homogeneous medium into a bubble layer and back again are calculated. It is shown that the near-bottom layer can effectively trap rays incident on it and ensure a waveguide propagation character. The presence of bubbles increases both the interval of angles at which the wave penetrates the layer and the interval of angles at which rays undergo total internal reflection and do not depart the layer. The acoustic field in the layer from a point source is calculated.
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| 5. |
- Gusev, V.A., et al.
(författare)
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The Field of Radiative Forces and the Acoustic Streaming in a Liquid Layer on a Solid Half-Space
- 2010
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Ingår i: Acoustical Physics. - : Pleiades Publishing. - 1063-7710 .- 1562-6865. ; 56:6, s. 861-870
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Tidskriftsartikel (refereegranskat)abstract
- The acoustic field and the field of radiative forces that are formed in a liquid layer on a solid substrate are calculated for the case of wave propagation along the interface. The calculations take into account the effects produced by surface tension, viscous stresses at the boundary, and attenuation in the liquid volume on the field characteristics. The dispersion equations and the velocities of wave propagation are determined. The radiative forces acting on a liquid volume element in a standing wave are calculated. The structure of streaming is studied. The effect of streaming on small size particles is considered, and the possibilities of ordered structure formation from them are discussed.
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| 6. |
- Petersen, Julian, et al.
(författare)
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A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology
- 2023
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- In this study we use comparative genomics to uncover a gene with uncharacterized function (1700011H14Rik/C14orf105/CCDC198), which we hereby name FAME (Factor Associated with Metabolism and Energy). We observe that FAME shows an unusually high evolutionary divergence in birds and mammals. Through the comparison of single nucleotide polymorphisms, we identify gene flow of FAME from Neandertals into modern humans. We conduct knockout experiments on animals and observe altered body weight and decreased energy expenditure in Fame knockout animals, corresponding to genome-wide association studies linking FAME with higher body mass index in humans. Gene expression and subcellular localization analyses reveal that FAME is a membrane-bound protein enriched in the kidneys. Although the gene knockout results in structurally normal kidneys, we detect higher albumin in urine and lowered ferritin in the blood. Through experimental validation, we confirm interactions between FAME and ferritin and show co-localization in vesicular and plasma membranes.
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| 7. |
- Richtman Feuerborn, Tatiana, et al.
(författare)
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Modern Siberian dog ancestry was shaped by several thousand years of Eurasian-wide trade and human dispersal
- 2021
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 118:39
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Tidskriftsartikel (refereegranskat)abstract
- Dogs have been essential to life in the Siberian Arctic for over 9,500 y, and this tight link between people and dogs continues in Siberian communities. Although Arctic Siberian groups such as the Nenets received limited gene flow from neighboring groups, archaeological evidence suggests that metallurgy and new subsistence strategies emerged in Northwest Siberia around 2,000 y ago. It is unclear if the Siberian Arctic dog population was as continuous as the people of the region or if instead admixture occurred, possibly in relation to the influx of material culture from other parts of Eurasia. To address this question, we sequenced and analyzed the genomes of 20 ancient and historical Siberian and Eurasian Steppe dogs. Our analyses indicate that while Siberian dogs were genetically homogenous between 9,500 to 7,000 y ago, later introduction of dogs from the Eurasian Steppe and Europe led to substantial admixture. This is clearly the case in the Iamal-Nenets region (Northwestern Siberia) where dogs from the Iron Age period (∼2,000 y ago) possess substantially less ancestry related to European and Steppe dogs than dogs from the medieval period (∼1,000 y ago). Combined with findings of nonlocal materials recovered from these archaeological sites, including glass beads and metal items, these results indicate that Northwest Siberian communities were connected to a larger trade network through which they acquired genetically distinctive dogs from other regions. These exchanges were part of a series of major societal changes, including the rise of large-scale reindeer pastoralism ∼800 y ago.
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| 8. |
- Rudenko, Oleg, et al.
(författare)
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Control of the Self-Assembly Processes in a Droplet of a Colloidal Solution by an Acoustic Field
- 2010
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Ingår i: Acoustical Physics. - : Pleiades Publishing. - 1063-7710 .- 1562-6865. ; 56:6, s. 935-941
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Tidskriftsartikel (refereegranskat)abstract
- The formation of structured films consisting of ensembles of micro- or nanoparticles and possessing preset functional characteristics is studied both experimentally and theoretically. The films are obtained by drying out droplets of colloidal solutions on a solid substrate under the acoustic effect produced by a standing SAW field.
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| 9. |
- Rudenko, Oleg, et al.
(författare)
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Self-similar solutions of a Burgers-type equation with quadratically cubic nonlinearity
- 2016
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Ingår i: Doklady. Mathematics. - : Maik Nauka/Interperiodica. - 1064-5624 .- 1531-8362. ; 93:1, s. 94-98
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Tidskriftsartikel (refereegranskat)abstract
- Self-similar solutions are found for a quadratically cubic second-order partial differential equation governing the behavior of nonlinear waves in various distributed systems, for example, in some metamaterials. They are compared with self-similar solutions of the Burgers equation. One of them describing a single unipolar pulse is shown to satisfy both equations. The other self-similar solutions of the quadratically cubic equation behave differently from the solutions of the Burgers equation. They are constructed by matching the positive and negative branches of the solution, so that the function itself and its first derivative are continuous. One of these solutions corresponds to an asymmetric solitary N-wave of the sonic shock type. Self-similar solutions of a quadratically cubic equation describing the propagation of cylindrically symmetric waves are also found.
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| 10. |
- Xie, Meng, et al.
(författare)
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The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.
- 2024
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Ingår i: Nature communications. - 2041-1723. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- The development of craniofacial skeletal structures is fascinatingly complex and elucidation of the underlying mechanisms will not only provide novel scientific insights, but also help develop more effective clinical approaches to the treatment and/or prevention of the numerous congenital craniofacial malformations. To this end, we performed a genome-wide analysis of RNA transcription from non-coding regulatory elements by CAGE-sequencing of the facial mesenchyme of human embryos and cross-checked the active enhancers thus identified against genes, identified by GWAS for the normal range human facial appearance. Among the identified active cis-enhancers, several belonged to the components of the PI3/AKT/mTORC1/autophagy pathway. To assess the functional role of this pathway, we manipulated it both genetically and pharmacologically in mice and zebrafish. These experiments revealed that mTORC1 signaling modulates craniofacial shaping at the stage of skeletal mesenchymal condensations, with subsequent fine-tuning during clonal intercalation. This ability of mTORC1 pathway to modulate facial shaping, along with its evolutionary conservation and ability to sense external stimuli, in particular dietary amino acids, indicate that the mTORC1 pathway may play a role in facial phenotypic plasticity. Indeed, the level of protein in the diet of pregnant female mice influenced the activity of mTORC1 in fetal craniofacial structures and altered the size of skeletogenic clones, thus exerting an impact on the local geometry and craniofacial shaping. Overall, our findings indicate that the mTORC1 signaling pathway is involved in the effect of environmental conditions on the shaping of craniofacial structures.
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