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Sökning: WFRF:(Hägerhed Engman Linda)

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1.
  • Angelova, Radostina A., et al. (författare)
  • The response rate in postal epidemiological studies in the context of national cultural behaviour
  • 2012
  • Ingår i: 10th International Conference on Healthy Buildings 2012. - 9781627480758 ; , s. 1429-1434
  • Konferensbidrag (refereegranskat)abstract
    • The purpose of this study was to analyse the effect of national cultural differences on the response rate, obtained in questionnaire based epidemiological studies on allergy and asthma, performed in Sweden (DBH) and Bulgaria (ALLHOME). The two studies used one and the same methodology, but the obtained response rate was different: 78.8% in DBH and 34.5% in ALLHOME. The differences in the obtained response rate and the reasons for these differences were analyzed on the basis of the Hofstede's cultural dimensions' indexes, which clearly show the distinction in the national cultural behaviour of people in Sweden and Bulgaria. It was found that national culture could strongly influence the response behaviour of people in epidemiological studies and Hofstede's indexes can be useful tool when designing and performing epidemiological studies, and in particular - questionnaire surveys.
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  • Bornehag, Carl-Gustaf, et al. (författare)
  • The association between asthma and allergic symptoms in children and phthalates in house dust : a nested case-control study
  • 2004
  • Ingår i: Journal of Environmental Health Perspectives. - : National Institute of Environmental Health Sciences (NIEHS). - 0091-6765 .- 1552-9924. ; 112:14, s. 1393-1397
  • Tidskriftsartikel (refereegranskat)abstract
    • Global phthalate ester production has increased from very low levels at the end of World War II to approximately 3.5 million metric tons/year. The aim of the present study was to investigate potential associations between persistent allergic symptoms in children, which have increased markedly in developed countries over the past three decades, and the concentration of phthalates in dust collected from their homes. This investigation is a case-control study nested within a cohort of 10,852 children. From the cohort, we selected 198 cases with persistent allergic symptoms and 202 controls without allergic symptoms. A clinical and a technical team investigated each child and her or his environment. We found higher median concentrations of butyl benzyl phthalate (BBzP) in dust among cases than among controls (0.15 vs. 0.12 mg/g dust). Analyzing the case group by symptoms showed that BBzP was associated with rhinitis (p = 0.001) and eczema (p = 0.001), whereas di(2-ethylhexyl) phthalate (DEHP) was associated with asthma (p = 0.022). Furthermore, dose-response relationships for these associations are supported by trend analyses. This study shows that phthalates, within the range of what is normally found in indoor environments, are associated with allergic symptoms in children. We believe that the different associations of symptoms for the three major phthalates-BBzP, DEHP, and di-n-butyl phthalate-can be explained by a combination of chemical physical properties and toxicologic potential. Given the phthalate exposures of children worldwide, the results from this study of Swedish children have global implications.
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