| 1. |
|
|
| 2. |
- Andersson, Annika, 1961-, et al.
(författare)
-
Challenges in project management : Grabbing the elephant
- 2007
-
Ingår i: Projects & Profits. ; 7:12, s. 33-37
-
Tidskriftsartikel (refereegranskat)abstract
- Projects and project management tend to have special meanings to the individuals involved in a specific line of research. This article reports on some topics covered in an informal Swedish network devoted to study project management. Ten topics are selected for discussion that fall into three broad categories—projects as practice, productivity in projects and education in a PM curriculum.
|
|
| 3. |
|
|
| 4. |
- Göransson, Viktoria, et al.
(författare)
-
Renal hyaluronan accumulation and hyaluronan synthase expression after ischaemia-reperfusion injury in the rat.
- 2004
-
Ingår i: Nephrol Dial Transplant. - 0931-0509. ; 19:4, s. 823-30
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Hyaluronan (HA) is a connective tissue component with unique water binding and pro-inflammatory properties. It has been suggested that HA is involved in normal renal water handling but also in several pathological conditions such as organ rejection and ischaemia-reperfusion (IR) injury. METHODS: In anaesthetized normal rats we investigated if renal cortical HA accumulation and the intrarenal distribution and expression of HA synthases (Has 1, 2 and 3) correlate with renal dysfunction after renal IR injury. After 20, 30 or 45 min of unilateral renal ischaemia and 72 h of reperfusion, renal function and cortical HA content were measured. Has 1, 2 and 3 mRNA were determined in control and IR kidneys subjected to 45 min ischaemia and 72 h reperfusion. RESULTS: IR kidneys had reduced urine concentrating ability, potassium excretion, glomerular filtration rate (GFR) and renal blood flow. On average, IR kidneys had more than 10 times higher amounts of cortical HA than the contralateral control kidney and their water content was elevated while medullary HA was largely unaffected. Has 2 expression in the cortex was heavily up-regulated in IR kidneys while Has 3 remained at control levels. Has 1 could never be detected. There was a direct correlation between the amount of cortical HA and the time period of ischaemia and also between the cortical amount of HA and depression of functional parameters. CONCLUSIONS: IR injury depresses parameters of renal function, which coincides with an elevated cortical HA content and Has 2 expression. The enhanced Has 2 expression indicates that the cortical HA accumulation is primarily dependent on increased HA synthesis and not impaired degradation/elimination. The water binding and pro-inflammatory properties of HA may contribute to renal dysfunction after IR.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
- Henein, Michael, et al.
(författare)
-
Aortic root, not valve, calcification correlates with coronary artery calcification in patients with severe aortic stenosis : a two-center study
- 2015
-
Ingår i: Atherosclerosis. - : Elsevier. - 0021-9150 .- 1879-1484. ; 243:2, s. 631-637
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The underlying pathology in aortic stenosis (AS) and coronary artery stenosis (CAS) is similar including atherosclerosis and calcification. We hypothesize that coronary artery calcification (CAC) is likely to correlate with aortic root calcification (ARC) rather than with aortic valve calcification (AVC), due to tissue similarity between the two types of vessel rather than with the valve leaflet tissue.MATERIAL AND METHODS: We studied 212 consecutive patients (age 72.5 ± 7.9 years, 91 females) with AS requiring aortic valve replacement (AVR) in two Heart Centers, who underwent multidetector cardiac CT preoperatively. CAC, AVC and ARC were quantified using Agatston scoring. Correlations were tested by Spearman's test and Mann-Whitney U-test was used for comparing different subgroups; bicuspid (BAV) vs tricuspid (TAV) aortic valve.RESULTS: CAC was present in 92%, AVC in 100% and ARC in 82% of patients. CAC correlated with ARC (rho = 0.51, p < 0.001) but not with AVC. The number of calcified coronary arteries correlated with ARC (rho = 0.45, p < 0.001) but not with AVC. 29/152 patients had echocardiographic evidence of BAV and 123 TAV, who were older (p < 0.001) but CAC was associated with TAV even after adjusting for age (p = 0.01). AVC score was associated with BAV after adjusting for age (p = 0.03) but ARC was not. Of the total cohort, 82 patients (39%) had significant coronary stenosis (>50%), but these were not different in the pattern of calcification from those without CAS. CAC was consistently higher in patients with risk factors for atherosclerosis compared to those without.CONCLUSION: The observed relationship between coronary and aortic root calcification suggests a diffuse arterial disease. The lack of relationship between coronary and aortic valve calcification suggests a different pathology.
|
|
| 9. |
- Lundvall, Suzanne, 1957-, et al.
(författare)
-
Öka skolidrotten till tre timmar i veckan
- 2010
-
Ingår i: Göteborgsposten. - 1103-9345. ; :9 maj
-
Tidskriftsartikel (populärvet., debatt m.m.)abstract
- En revidering av grundskolans kursplaner, som är på gång, ska göra dessa mer tydliga och begripliga för lärare, elever och föräldrar. Det är ett lovvärt motiv! Men den föreslagna kursplanen i idrott och hälsa ger anledning till stor oro, skriver bland andra Peter Friberg, professor och överläkare, Sahlgrenska universitetssjukhuset.
|
|
| 10. |
- van Ettinger-Veenstra, Helene M, et al.
(författare)
-
Right-hemispheric brain activation correlates to language performance
- 2010
-
Ingår i: NEUROIMAGE. - : Elsevier BV. - 1053-8119. ; 49:4, s. 3481-3488
-
Tidskriftsartikel (refereegranskat)abstract
- Language function in the right-hemispheric homologues of Brocas and Wernickes areas does not only correlate with left-handedness or pathology, but occurs naturally in right-handed healthy subjects as well. In the current study, two non-invasive methods of assessing language lateralization are correlated with behavioral results in order to link hemispheric dominance to language ability in healthy subjects. Functional magnetic resonance imaging (fMRI) together with a sentence-completion paradigm was used to determine region-specific lateralization indices in the left- and right-sided Brocas and Wernickes areas, the frontal temporal lobe, the anterior cingulate cortex and the parietal lobe. In addition, dichotic listening results were used to determine overall language lateralization and to strengthen conclusions by correlating with fMRI indices. Results showed that fMRI lateralization in the superior parietal, the posterior temporal, and the anterior cingulate cortices correlated to dichotic listening. A decreased right ear advantage (REA), which indicates less left- hemispheric dominance in language, correlated with higher performance in most administered language tasks, including reading, language ability, fluency, and non-word discrimination. Furthermore, right hemispheric involvement in the posterior temporal lobe and the homologue of Brocas area suggests better performance in behavioral language tasks. This strongly indicates a supportive role of the right-hemispheric counterparts of Brocas and Wernickes areas in language performance.
|
|
