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| 2. |
- Glauser, Roland, et al.
(författare)
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Immediate occlusal loading of Brånemark TiUnite implants placed predominantly in soft bone: 1-year results of a prospective clinical study.
- 2003
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Ingår i: Clinical implant dentistry and related research. - 1523-0899. ; 5 Suppl 1, s. 47-56
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The original Brånemark protocol for dental implant treatment was based on submerged healing prior to loading. However, immediate loading has been reported possible with high success rates for various indications, provided that good bone quality and quantity are present. In many of these studies, machined-surface implants have been used. Recently, a new surface texture has been developed, based on an oxidation processing, that aims to enhance the early bone response (Brånemark System Mk IV TiUnite , Nobel Biocare AB, Gothenburg, Sweden). It has been documented that this surface texture may help to better maintain primary implant stability during the early healing period and that secondary implant stability can be reached earlier compared with results when using a machined surface. Such a positive influence on implant stability might be an advantage when applying an immediate-loading protocol, especially in soft bone regions where a tendency toward reduced success rates has been reported. PURPOSE: The aim of this report was to present the short-term success rates of TiUnite-surfaced immediate occlusally loaded Brånemark System Mk IV implants placed in various regions of the jaws. MATERIALS AND METHODS: Thirty-eight patients received a total of 51 prosthetic reconstructions, all of which were connected on the day the implants were inserted. Of these, 20 were single-tooth restorations, 30 were fixed partial dentures, and 1 was a complete fixed lower jaw restoration. These prostheses were supported by 102 Brånemark System Mk IV TiUnite implants (38 maxillary and 64 mandibular), the majority of which were placed in posterior regions (88%) and mainly in soft bone (76%). Cutting resistance measurements were performed during implant insertion, and resonance frequency measurements were conducted during the course of the study. Furthermore, radiographic examinations were performed in connection with the delivery of the prostheses and at the 1-, 6-, and 12-month follow-up visits. This article reports on the results after 1 year of loading. RESULTS: Three maxillary implants were removed, although stable, in one patient at the 8-week follow-up because of postoperative infection in the adjacent area of guided bone regeneration (GBR). This resulted in a cumulative success rate of the implants of 97.1% after 1 year of prosthetic loading. The mean marginal bone resorption after 1 year of loading was 1.2 +/- 0.9 mm (SD). CONCLUSIONS: The applied immediate loading protocol in combination with a slightly tapered implant and a modified implant surface texture was shown to be a successful treatment alternative even in regions exhibiting soft bone.
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| 3. |
- Glauser, Roland, et al.
(författare)
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Periimplant soft tissue barrier at experimental one-piece mini-implants with different surface topography in humans: A light-microscopic overview and histometric analysis.
- 2005
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Ingår i: Clinical implant dentistry and related research. - 1523-0899. ; 7 Suppl 1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Following connection to the oral cavity, osseointegrated dental implants and surrounding tissues are exposed to microbiologic and biomechanical challenges. The establishment of a firm functional periimplant soft tissue barrier (PSTB) is considered to be important to protect the implant's interface from invasion of bacteria. The current knowledge on the histologic architecture of the PSTB is mainly based on animal experiments. PURPOSE: The aim of this study was to histologically characterize the PSTB formed in humans around experimental one-piece mini-implants with different surface topography. MATERIALS AND METHODS: Five patients received a total of 12 experimental titanium, one-piece mini-implants with an oxidized (n = 4), an acid-etched (n = 4), or a machined (n = 4) surface distal to therapeutic implants. Following transmucosal healing of 8 weeks and at abutment connection of the regular implants, the mini-implants were harvested with a layer of surrounding hard and soft tissue. The specimens were fixed and processed for histologic sectioning according to standard procedures. The most central bucco-oral section cut in the long axis was used for morphologic analyses of the PSTB. The vertical soft tissue morphology was quantified using histometric measurements. RESULTS: The overall height of the soft tissue, that is, the biologic width, was around 4 to 4.5 mm and consisted of an epithelial and a supracrestal connective tissue barrier. The junctional epithelium established the attachment to the implant surface, whereas the collagen fibers and fibroblasts of the connective tissue seal were oriented parallel to the implant. The epithelial attachment was shorter at the oxidized and acid-etched surfaces compared with the machined surfaces. Accordingly, the oxidized and acid-etched mini-implants exhibited a longer zone of connective tissue seal. CONCLUSION: The periimplant soft tissue formed at the experimental one-piece mini-implants in humans was of a character similar to that described in animal studies. The oxidized and acid-etched implants revealed less epithelial downgrowth and longer connective tissue seal than machined implants.
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| 4. |
- Glauser, Roland, et al.
(författare)
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Resonance frequency analysis of implants subjected to immediate or early functional occlusal loading. Successful vs. failing implants.
- 2004
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Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 15:4, s. 428-34
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: The objective of this study was to analyze the development of implant stability by repeated resonance frequency analysis (RFA) measurements during 1 year in 23 patients treated according to an immediate/early-loading protocol. The objective was also to evaluate the possible differences between failing and successful implants. MATERIAL AND METHODS: Eighty-one Brånemark System implants were placed in 23 patients for immediate/early-occlusal loading in all jaw regions. Thirty of the implants were placed in extraction sockets and 62 were subjected to GBR procedures. Apart from clinical and radiographic examinations, the patients were followed with RFA at placement, prosthesis connection and after 1-3, 6 and 12 months. Statistical analyses were carried out to study the possible differences between implants that failed during the study period and implants that remained successful. RESULTS: Nine implants failed (11.2%) during the 1 year of loading. RFA showed a distinct different pattern between the implants that remained stable and the implants that were lost. The implants that failed during the course of the study showed a significantly lower stability already after 1 month. CONCLUSION: Within the limitations of this study, it is concluded that failing implants show a continuous decrease of stability until failure. Low RFA levels after 1 and 2 months seem to indicate an increased risk for future failure. This information may be used to avoid implant failure in the future by unloading implants with decreasing degree of stability with time as diagnosed with the RFA technique.
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| 5. |
- Hämmerle, Christoph H F, et al.
(författare)
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Biology of soft tissue wound healing and regeneration : consensus report of group 1 of the 10th European workshop on periodontology
- 2014
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Ingår i: Journal of Clinical Periodontology. - : John Wiley & Sons. - 0303-6979 .- 1600-051X. ; 41:s15, s. S1-S5
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- BACKGROUND:The scope of this consensus was to review the biological processes of soft tissue wound healing in the oral cavity and to histologically evaluate soft tissue healing in clinical and pre-clinical models. AIMS:To review the current knowledge regarding the biological processes of soft tissue wound healing at teeth, implants and on the edentulous ridge. Furthermore, to review soft tissue wound healing at these sites, when using barrier membranes, growth and differentiation factors and soft tissue substitutes. COLLECTION OF DATA:Searches of the literature with respect to recessions at teeth and soft tissue deficiencies at implants, augmentation of the area of keratinized tissue and soft tissue volume were conducted. The available evidence was collected, categorized and summarized. FUNDAMENTAL PRINCIPLES OF ORAL SOFT TISSUE WOUND HEALING:Oral mucosal and skin wound healing follow a similar pattern of the four phases of haemostasis, inflammation, proliferation and maturation/matrix remodelling. The soft connective tissue determines the characteristics of the overlaying oral epithelium. Within 7-14 days, epithelial healing of surgical wounds at teeth is completed. Soft tissue healing following surgery at implants requires 6-8 weeks for maturation. The resulting tissue resembles scar tissue. Well-designed pre-clinical studies providing histological data have been reported describing soft tissue wound healing, when using barrier membranes, growth and differentiation factors and soft tissue substitutes. Few controlled clinical studies with low numbers of patients are available for some of the treatments reviewed at teeth. Whereas, histological new attachment has been demonstrated in pre-clinical studies resulting from some of the treatments reviewed, human histological data commonly report a lack of new attachment but rather long junctional epithelial attachment and connective tissue adhesion. Regarding soft tissue healing at implants human data are very scarce. CONCLUSIONS:Oral soft tissue healing at teeth, implants and the edentulous ridge follows the same phases as skin wound healing. Histological studies in humans have not reported new attachment formation at teeth for the indications studied. Human histological data of soft tissue wound healing at implants are limited. CLINICAL RECOMMENDATIONS:The use of barriers membranes, growth and differentiation factors and soft tissue substitutes for the treatment of localized gingival/mucosal recessions, insufficient amount of keratinized tissue and insufficient soft tissue volume is at a developing stage.
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| 6. |
- Hämmerle, Christoph H.F., et al.
(författare)
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Submerged and transmucosal healing yield the same clinical outcomes with two-piece implants in the anterior maxilla and mandible: Interim 1-year results of a randomized, controlled clinical trial
- 2012
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Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 23:2, s. 211-219
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To test whether or not transmucosal healing at two-piece implants is as successful as submerged placement regarding crestal bone levels and patient satisfaction. Material and methods: Adults requiring implants in the anterior maxilla or mandible in regions 21-25, 11-15, 31-35 or 41-45 (WHO) were recruited for this randomized, controlled multi-center clinical trial of a 5-year duration. Randomization was performed at implantation allowing for either submerged or transmucosal healing. Final reconstructions were seated 6 months after implantation. Radiographic interproximal crestal bone levels and peri-implant soft tissue parameters were measured at implant placement (IP) (baseline), 6 and 12 months. Patient satisfaction was assessed by a questionnaire. A two-sided t-test (80% power, significance level α=0.05) was performed on bone-level changes at 6 and 12 months. Results: One hundred and twenty-seven subjects were included in the 12-month analysis (submerged [S]: 52.5%, transmucosal [TM]: 47.2%). From IP to 6 months, the change in the crestal bone level was -0.32mm (P<0.001) for the S group and -0.29mm (P<0.001) for the TM group. From IP to 12 months, bone-level changes were statistically significant in both groups (S -0.47 mm, P<0.001; TM -0.48mm, P<0.001). The mean differences of change in the bone levels between the two groups were not statistically significant at either time point, indicating the equivalence of both procedures. For both groups, very good results were obtained for soft tissue parameters and for patient satisfaction. Conclusions: Transmucosal healing of two-piece implants is as successful as the submerged healing mode with respect to tissue integration and patient satisfaction within the first 12 months after IP. © 2011 John Wiley & Sons A/S.
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| 7. |
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| 8. |
- Hämmerle, Christoph H F, et al.
(författare)
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Timing of Implant Placement
- 2008
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Ingår i: Clinical Periodontology and Implant Dentistry. - Oxford : Blackwell Munksgaard. - 9781405160995 ; , s. 1053-1067
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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