| 1. |
- Alling, Björn, et al.
(författare)
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A theoretical investigation of mixing thermodynamics, age-hardening potential, and electronic structure of ternary (M1-xMxB2)-M-1-B-2 alloys with AlB2 type structure
- 2015
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Ingår i: Scientific Reports. - : Nature Publishing Group: Open Access Journals - Option C / Nature Publishing Group. - 2045-2322. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Transition metal diborides are ceramic materials with potential applications as hard protective thin films and electrical contact materials. We investigate the possibility to obtain age hardening through isostructural clustering, including spinodal decomposition, or ordering-induced precipitation in ternary diboride alloys. By means of first-principles mixing thermodynamics calculations, 45 ternary (M1-xMxB2)-M-1-B-2 alloys comprising (MB2)-B-i (M-i = Mg, Al, Sc, Y, Ti, Zr, Hf, V, Nb, Ta) with AlB2 type structure are studied. In particular Al1-xTixB2 is found to be of interest for coherent isostructural decomposition with a strong driving force for phase separation, while having almost concentration independent a and c lattice parameters. The results are explained by revealing the nature of the electronic structure in these alloys, and in particular, the origin of the pseudogap at E-F in TiB2, ZrB2, and HfB2.
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| 2. |
- Ambrosetti, Elena, et al.
(författare)
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A DNA-nanoassembly-based approach to map membrane protein nanoenvironments
- 2020
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Ingår i: Nature Nanotechnology. - Stockholm : Karolinska Institutet, Dept of Medical Biochemistry and Biophysics. - 1748-3387 .- 1748-3395. ; 120:3, s. 273A-274A
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Tidskriftsartikel (refereegranskat)abstract
- Most proteins at the plasma membrane are not uniformly distributed but localize to dynamic domains of nanoscale dimensions. To investigate their functional relevance, there is a need for methods that enable comprehensive analysis of the compositions and spatial organizations of membrane protein nanodomains in cell populations. Here we describe the development of a non-microscopy based method for ensemble analysis of membrane protein nanodomains. The method, termed NANOscale DEciphEring of membrane Protein nanodomains (NanoDeep), is based on the use of DNA nanoassemblies to translate membrane protein organization information into a DNA sequencing readout. Using NanoDeep, we characterised the nanoenvironments of Her2, a membrane receptor of critical relevance in cancer. Importantly, we were able to modulate by design the inventory of proteins analysed by NanoDeep. NanoDeep has the potential to provide new insights into the roles of the composition and spatial organization of protein nanoenvironments in the regulation of membrane protein function.
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| 3. |
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| 4. |
- Assarsson, Rebecka, et al.
(författare)
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Gender inequality and adolescent suicide ideation across Africa, Asia, the South Pacific and Latin America : a cross-sectional study based on the Global School Health Survey (GSHS)
- 2019
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Ingår i: Global Health Action. - : Taylor & Francis. - 1654-9716 .- 1654-9880. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Background: Suicide ideation is a health issue affecting adolescents worldwide. There are significant variations in suicide ideation between countries and genders, which have not been fully explained. Research is especially lacking in countries outside Europe and North America. Gender equality has been shown to matter in other aspects of adolescent mental health, such as life satisfaction, but has not been researched in relation to suicide ideation at national level.Objective: To investigate how national gender inequality is related to self-reported suicide ideation among adolescents, and whether this association differs between boys and girls.Methods: This is a cross-national, cross-sectional study using individual survey data from the Global School-based Student Health Survey, a survey in Africa, Asia, Latin America and the South Pacific, developed and supported by among others the WHO and the CDC; connecting this to national data: the gender inequality index from the UNDP; controlling for GDP per capita and secondary school enrolment. The data was analysed using a multilevel logistic regression method and included 149,306 students from 37 countries.Results: Higher national gender inequality, as measured by the gender inequality index, was significantly associated with a higher likelihood of suicide ideation in both girls and boys (odds ratio: 1.38 p-value: 0.015), but for girls and both sexes this was only after adjusting for selection bias due to secondary school enrolment (as well as GDP/capita). Interaction models showed that this association was stronger in boys than in girls.Conclusions: National gender inequality seems to be associated with higher levels of suicide ideation among adolescents in mainly low- and middle-income countries, especially among boys.
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| 6. |
- Baranowska-Rataj, Anna, 1980-, et al.
(författare)
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Do consequences of parental job displacement for infant health vary across local economic contexts?
- 2024
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Ingår i: RSF: The Russell Sage Foundation Journal of the Social Sciences. - New York : Russell Sage Foundation. - 2377-8253 .- 2377-8261. ; 10:1, s. 57-80
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Tidskriftsartikel (refereegranskat)abstract
- This study examines the consequences of parental job displacement for birth outcomes and investigates how the effects vary with regional unemployment rates. We use Swedish register data and exploit plausibly exogenous variation caused by workplace closure to reduce the bias related to reverse causality and confounding. The differences in birth outcomes between children of parents who experienced job displacement and children of parents who were not displaced turn out to be quite modest. Even in the most disadvantaged regions, with the highest unemployment rates, parental job displacement is not harmful for health at birth. We relate these findings to the institutional setting in Sweden and discuss policy implications for the United States.
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| 7. |
- Baranowska-Rataj, Anna, 1980-, et al.
(författare)
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Effects of parental job loss on children’s mental health : the role of latency, timing and cumulative effects
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Crossover effects of critical life events within families have received growing attention in life-courseresearch. A parent losing a job is among the most distressing events that can befall a family, butexisting research has reached discrepant conclusions concerning if, and if so how, this affects childmental health. Drawing on insights from models of intra-family influence and life courseepidemiological models, we ask if parental job loss have latent or long-term effects on child mentalhealth, if the effects are conditional on the timing of the job loss, and if repeated job losses havecumulative effects.We use intergenerationally linked Swedish register data combined with entropy balance andstructural nested mean models for the analyses. The data allow us to track 400,000 children over 14years and thereby test different life-course models of crossover effects. We identify involuntary joblosses using information on workplace closures, thus reducing the risk of confounding.Results show that paternal but not maternal job loss significantly increases the risk of mental healthproblems among children, that the average effects are modest in size (less than 4% in relativeterms), that they materialize only after some years, and that they are driven by children aged 6-10years. Moreover, we find evidence of cumulative effects, but also of declining marginal harm ofadditional job losses over the life course.
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| 8. |
- Baranowska-Rataj, Anna, 1980-, et al.
(författare)
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Parental unemployment and adolescent wellbeing : The moderating role of educational policies
- 2021
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Crossover effects of parental unemployment on wellbeing of children attract growing attention in research on social inequalities. Recent economic crises call for identifying policies that mitigate the adverse effects of unemployment. Building on the theoretical insights from Capability Approach, we examine the relationship between parental unemployment and wellbeing of adolescents across countries with different educational policies. We use multilevel modelling and microdata on economic and subjective wellbeing of household members from the European Union Statistics on Income and Living Conditions (EU-SILC). We combine microdata on 45,992 adolescents in 32 countries with macro-level indicators of educational policies.We find that parental unemployment is associated with lower adolescent wellbeing, but the magnitude of this association varies depending on access to financial support for participation in education. Adolescents who receive educational allowances and who live in countries with broader access to such support are less harmed by parental unemployment.
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| 9. |
- Baranowska-Rataj, Anna, 1980-, et al.
(författare)
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Parental unemployment and adolescents' subjective wellbeing : the moderating role of educational policies
- 2024
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Ingår i: European Sociological Review. - : Oxford University Press. - 0266-7215 .- 1468-2672. ; 40:2, s. 276-292
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Tidskriftsartikel (refereegranskat)abstract
- Crossover effects of parental unemployment on subjective wellbeing of children attract growing attention in research on social inequalities. Recent economic crises call for identifying policies that mitigate the adverse effects of unemployment. Building on the theoretical insights from Capability Approach, we examine the relationship between parental unemployment and subjective wellbeing of adolescents across countries with different educational policies. We use multilevel modelling and data from the European Union Statistics on Income and Living Conditions (EU-SILC). We combine microdata on 45,992 adolescents in 32 countries with macro-level indicators of educational policies. We find that parental unemployment is associated with lower subjective wellbeing among adolescents, but the magnitude of this association varies depending on access to financial support for participation in education. Adolescents who receive educational allowances and who live in countries with broader access to such support are less harmed by parental unemployment.
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| 10. |
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