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Träfflista för sökning "WFRF:(Harrow Ian) "

Sökning: WFRF:(Harrow Ian)

  • Resultat 1-8 av 8
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1.
  • Birney, Ewan, et al. (författare)
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
  • 2007
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7146, s. 799-816
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function.
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2.
  • Abd Nikooie Pour, Mina, et al. (författare)
  • Results of the Ontology Alignment Evaluation Initiative 2021
  • 2021
  • Ingår i: Proceedings of the 16th International Workshop on Ontology Matching co-located with the 20th International Semantic Web Conference (ISWC 2021), Virtual conference, October 25, 2021. - : CEUR-WS.org. ; , s. 62-108, s. 62-108
  • Konferensbidrag (refereegranskat)abstract
    • The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.g., blind evaluation, open evaluation, or consensus).The OAEI 2021 campaign offered 13 tracks and was attended by 21 participants.This paper is an overall presentation of that campaign. 
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3.
  • Abd Nikooie Pour, Mina, et al. (författare)
  • Results of theOntology Alignment Evaluation Initiative 2020
  • 2020
  • Ingår i: Proceedings of the 15th International Workshop on Ontology Matching. - Aachen, Germany : CEUR Workshop proceedings. ; , s. 92-138
  • Konferensbidrag (refereegranskat)abstract
    • The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.g., blind evaluation, open evaluation, or consensus).The OAEI 2020 campaign offered 12 tracks with 36 test cases, and was attended by 19 participants. This paper is an overall presentation of that campaign. 
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5.
  • Achichi, Manel, et al. (författare)
  • Results of the Ontology Alignment Evaluation Initiative 2017
  • 2017
  • Ingår i: Proceedings of the 12th International Workshop on Ontology Matching co-located with the 16th International Semantic Web Conference (ISWC 2017). - Aachen, Germany : CEUR Workshop Proceedings. ; , s. 61-113
  • Konferensbidrag (refereegranskat)
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6.
  • Algergawy, Alsayed, et al. (författare)
  • Results of the Ontology Alignment Evaluation Initiative 2018
  • 2018
  • Ingår i: Proceedings of the 13th International Workshop on Ontology Matching. - Aachen, Germany : CEUR Workshop Proceedings. ; , s. 76-116
  • Konferensbidrag (refereegranskat)abstract
    • The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity (from simple thesauri to expressive OWL ontologies) and use different evaluation modalities (e.g., blind evaluation, open evaluation, or consensus). The OAEI 2018 campaign offered 12 tracks with 23 test cases, and was attended by 19 participants. This paper is an overall presentation of that campaign.
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7.
  • Algergawy, Alsayed, et al. (författare)
  • Results of the Ontology Alignment Evaluation Initiative 2019
  • 2019
  • Ingår i: Proceedings of the 14th International Workshop on Ontology Matchingco-located with the 18th International Semantic Web Conference (ISWC 2019). - Aachen : CEUR Workshop Proceedings. ; , s. 46-85
  • Konferensbidrag (refereegranskat)abstract
    • The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity (from simple thesauri to expressive OWL ontologies) and use different evaluation modalities (e.g., blind evaluation,open evaluation, or consensus). The OAEI2019 campaign offered 11 tracks with 29 test cases, and was attended by 20 participants. This paper is an overall presentation of that campaign.
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8.
  • Bateman, Alex, et al. (författare)
  • RNAcentral: A vision for an international database of RNA sequences.
  • 2011
  • Ingår i: RNA (New York, N.Y.). - : Cold Spring Harbor Laboratory. - 1469-9001 .- 1355-8382. ; 17:11, s. 1941-6
  • Tidskriftsartikel (refereegranskat)abstract
    • During the last decade there has been a great increase in the number of noncoding RNA genes identified, including new classes such as microRNAs and piRNAs. There is also a large growth in the amount of experimental characterization of these RNA components. Despite this growth in information, it is still difficult for researchers to access RNA data, because key data resources for noncoding RNAs have not yet been created. The most pressing omission is the lack of a comprehensive RNA sequence database, much like UniProt, which provides a comprehensive set of protein knowledge. In this article we propose the creation of a new open public resource that we term RNAcentral, which will contain a comprehensive collection of RNA sequences and fill an important gap in the provision of biomedical databases. We envision RNA researchers from all over the world joining a federated RNAcentral network, contributing specialized knowledge and databases. RNAcentral would centralize key data that are currently held across a variety of databases, allowing researchers instant access to a single, unified resource. This resource would facilitate the next generation of RNA research and help drive further discoveries, including those that improve food production and human and animal health. We encourage additional RNA database resources and research groups to join this effort. We aim to obtain international network funding to further this endeavor.
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  • Resultat 1-8 av 8

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