| 1. |
- Eberhardson, Michael, et al.
(författare)
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Tumour necrosis factor inhibitors in Crohn's disease and the effect on surgery rates
- 2022
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Ingår i: Colorectal Disease. - : Wiley. - 1462-8910 .- 1463-1318. ; 24:4, s. 470-483
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Surgery is an important therapeutic option for Crohn's disease. The need for first bowel surgery seems to have decreased with the introduction of tumour necrosis factor inhibitors (TNFi; adalimumab or infliximab). However, the impact of TNFi on the need for intestinal surgery in Crohn's disease patients irrespective of prior bowel resection is not known. The aim of this work is to compare the incidence of bowel surgery in Crohn's disease patients who remain on TNFi treatment versus those who discontinue it. Method: We performed a nationwide register-based observational cohort study in Sweden of all incident and prevalent cases of Crohn's disease who started first-line TNFi treatment between 2006 and 2017. Patients were categorized according to TNFi treatment retention less than or beyond 1 year. The study cohort was evaluated with regard to incidence of bowel surgery from 12 months after the first ever TNFi dispensation. Results: We identified 5003 Crohn's disease patients with TNFi exposure: 3748 surgery naïve and 1255 with bowel surgery prior to TNFi initiation. Of these patients, 7% (n = 353) were subjected to abdominal surgery during the first 12 months after the start of TNFi and were subsequently excluded from the main analysis. A majority (62%) continued TNFi for 12 months or more. Treatment with TNFi for less than 12 months was associated with a significantly higher surgery rate compared with patients who continued on TNFi for 12 months or more (hazard ratio 1.26, 95% CI 1.09–1.46; p = 0.002). Conclusion: Treatment with TNFi for less than 12 months was associated with a higher risk of bowel surgery in Crohn's disease patients compared with those who continued TNFi for 12 months or more.
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| 2. |
- Aaltonen, T., et al.
(författare)
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Combination of Tevatron Searches for the Standard Model Higgs Boson in the W+W- Decay Mode
- 2010
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 104:6, s. 061802-
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Tidskriftsartikel (refereegranskat)abstract
- We combine searches by the CDF and D0 Collaborations for a Higgs boson decaying to W+W-. The data correspond to an integrated total luminosity of 4.8 (CDF) and 5.4 (D0) fb(-1) of p (p) over bar collisions at root s = 1.96 TeV at the Fermilab Tevatron collider. No excess is observed above background expectation, and resulting limits on Higgs boson production exclude a standard model Higgs boson in the mass range 162-166 GeV at the 95% C.L.
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| 3. |
- Abazov, M, et al.
(författare)
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A novel method for modeling the recoil in W boson events at hadron colliders
- 2009
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 609:2-3, s. 250-262
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Tidskriftsartikel (refereegranskat)abstract
- We present a new method for modeling the hadronic recoil in W -> lv events produced at hadron colliders. The recoil is chosen from a library of recoils in Z -> ll data events and overlaid on a simulated W -> lv event. Implementation of this method requires that the data recoil library describe the proper-ties of the measured recoil as a function of the true, rather than the measured, transverse momentum of the boson. We address this issue using a multidimensional Bayesian unfolding technique. We estimate the statistical and systematic uncertainties from this method for the W boson mass and width measurements assuming 1 fb(-1) of data from the Fermilab Tevatron. The uncertainties are found to be small and comparable to those of a more traditional parameterized recoil model. For the highprecision measurements that will be possible with data from Run 11 of the Fermilab Tevatron and from the CERN LHC, the method presented in this paper may be advantageous, since it does not require an understanding of the measured recoil from first principles.
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| 4. |
- Abazov, M, et al.
(författare)
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Combination of t(t)over-bar cross section measurements and constraints on the mass of the top quark and its decays into charged Higgs bosons
- 2009
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Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 80, s. 071102-
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Tidskriftsartikel (refereegranskat)abstract
- We combine measurements of the top quark pair production cross section in p (p) over bar collisions in the l + jets, ll, and tau l final states ( where l is an electron or muon) at a center of mass energy of root s = 1.96 TeV in 1 fb(-1) of data collected with the D0 detector. For a top quark mass of 170 GeV/c(2), we obtain sigma(t (t) over bar) = 8.18(-0.87)(+0.98) pb in agreement with the theoretical prediction. Based on predictions from higher order quantum chromodynamics, we extract a mass for the top quark from the combined t (t) over bar cross section, consistent with the world average of the top quark mass. In addition, the ratios of t (t) over bar cross sections in different final states are used to set upper limits on the branching fractions B(t -> H(+)b -> tau(+) vb) and B(t -> H(+)b -> c (s) over barb) as a function of the charged Higgs boson mass.
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| 5. |
- Abazov, M, et al.
(författare)
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Direct Measurement of the Mass Difference between Top and Antitop Quarks
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:13, s. 132001-
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Tidskriftsartikel (refereegranskat)abstract
- We present a measurement of the mass difference between t and (t) over bar quarks in lepton + jets final states of t (t) over bar events in 1 fb(-1) of data collected with the D0 detector from Fermilab Tevatron Collider p (p) over bar collisions at root s = 1.96 TeV. The measured mass difference of 3.8 +/- 3.7 GeV is consistent with the equality of t and (t) over bar masses. This is the first direct measurement of a mass difference between a quark and its antiquark partner.
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| 6. |
- Abazov, M, et al.
(författare)
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Direct Measurement of the W Boson Width
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:23, s. 231802-
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Tidskriftsartikel (refereegranskat)abstract
- We present a direct measurement of the width of the W boson using the shape of the transverse mass distribution of W -> e nu candidate events. Data from approximately 1 fb(-1) of integrated luminosity recorded at s=1.96 TeV by the D0 detector at the Fermilab Tevatron pp collider are analyzed. We use the same methods and data sample that were used for our recently published W boson mass measurement, except for the modeling of the recoil, which is done with a new method based on a recoil library. Our result, 2.028 +/- 0.072 GeV, is in agreement with the predictions of the standard model.
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| 7. |
- Abazov, M, et al.
(författare)
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Evidence of WW and WZ Production with lepton plus jets Final States in pp Collisions at root s=1.96 TeV
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:16, s. 161801-
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Tidskriftsartikel (refereegranskat)abstract
- We present first evidence for WW+WZ production in lepton+jets final states at a hadron collider. The data correspond to 1.07 fb(-1) of integrated luminosity collected with the D0 detector at the Fermilab Tevatron in pp collisions at root s=1.96 TeV. The observed cross section for WW+WZ production is 20.2 +/- 4.5 pb, consistent with the standard model and more precise than previous measurements in fully leptonic final states. The probability that background fluctuations alone produce this excess is < 5.4x10(-6), which corresponds to a significance of 4.4 standard deviations.
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| 8. |
- Abazov, M, et al.
(författare)
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Measurement of B-s(0) Mixing Parameters from the Flavor-Tagged Decay B-s(0)-> J/psi phi
- 2008
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 101:24, s. 241801-:101, s. 241801-
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Tidskriftsartikel (refereegranskat)abstract
- From an analysis of the flavor-tagged decay B-s(0)-> J/psi phi we obtain the width difference between the B-s(0) light and heavy mass eigenstates, Delta Gamma(s)=0.19 +/- 0.07(stat)(-0.01)(+0.02)(syst) ps(-1), and the CP-violating phase, phi(s)=-0.57(-0.30)(+0.24)(stat)(-0.02)(+0.08)(syst). The allowed 90% CL intervals of Delta Gamma(s) and phi(s) are 0.06
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| 9. |
- Abazov, M, et al.
(författare)
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Measurement of differential Z/gamma* plus jet plus X cross sections in p(p)over-bar collisions at root S=1.96 TeV
- 2008
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 669:5, s. 278-286
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Tidskriftsartikel (refereegranskat)abstract
- We present new measurements of differential cross sections for Z/gamma* (-> mu mu) + jet + X production in a 1 fb(-1) data sample collected with the DO detector in p (p) over bar collisions at root s = 1.96 TeV. Results include the first measurements differential in the Z/gamma* transverse momentum and rapidity, as well as new measurements differential in the leading jet transverse momentum and rapidity. Next-to-leading order perturbative QCD predictions are compared to the measurements, and reasonable agreement is observed, except in the region of low Z/gamma* transverse momentum. Predictions from two event generators based on matrix elements and parton showers, and one pure parton shower event generator are also compared to the measurements. These show significant overall normalization differences to the data and have varied success in describing the shape of the distributions.
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| 10. |
- Abazov, M, et al.
(författare)
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Measurement of Dijet Angular Distributions at s=1.96 TeV and Searches for Quark Compositeness and Extra Spatial Dimensions
- 2009
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:19, s. 191803-
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Tidskriftsartikel (refereegranskat)abstract
- We present the first measurement of dijet angular distributions in pp collisions at s=1.96 TeV at the Fermilab Tevatron Collider. The measurement is based on a dataset corresponding to an integrated luminosity of 0.7 fb(-1) collected with the D0 detector. Dijet angular distributions have been measured over a range of dijet masses, from 0.25 TeV to above 1.1 TeV. The data are in good agreement with the predictions of perturbative QCD and are used to constrain new physics models including quark compositeness, large extra dimensions, and TeV-1 scale extra dimensions. For all models considered, we set the most stringent direct limits to date.
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