| 1. |
- Koivula, Tiia, et al.
(författare)
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Sex comparison of white blood cell responses to acute vigorous-intensity aerobic exercise
- 2023
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Ingår i: Acta Physiologica. - Chichester : Wiley-Blackwell. - 1748-1708 .- 1748-1716. ; 239:S728, s. 44-45
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Tidskriftsartikel (refereegranskat)abstract
- Background: It is widely accepted that exercise alters the number and function of circulating leukocytes, and many factors are suggested to influence this phenomenon. The aim here was to compare white blood cell mobilization between sexes after acute vigorous-intensity exercise bout.Methods: The study included healthy and physically active subjects, 10 men (aged 26 (SD 7) years) and 10 women (aged 33 (SD 8) years). Participants performed a 30-min cycling ergometer exercise at 70% VO2max. Blood samples were drawn at rest and 3 min, 1 and 2 h post-exercise. Changes in total leukocyte, neutrophil, lymphocyte, monocyte, eosinophil, and basophil count were analyzed and corrected for plasma volume change.Results: Women had higher lymphocyte counts and lower eosinophil proportion of total leukocytes compared to men at all time points. Acute exercise significantly increased the number of total leukocytes and all leukocyte subpopulations excluding eosinophils in both women and men. The mobilization of all leukocyte subpopulations was similar in both sexes, but mobilization of total leukocytes, as a percentage change from rest, was greater in men. Increase in total leukocyte, neutrophil, and lymphocyte counts correlated positively with lactate concentration at 3-min timepoint and decrease in lymphocyte and basophil count after exercise correlated negatively with mean exercising heart rate in both sexes.Conclusion: Our findings indicate that mobilization of total leukocytes is greater in men. The sex-difference however is small and not observed in any leukocyte subpopulations. Further, exercise intensity driven physiological perturbation has a role in immune cell mobilization.
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| 2. |
- Dabaieh, Marwa, et al.
(författare)
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A comparative study of life cycle carbon emissions and embodied energy between sun-dried bricks and fired clay bricks
- 2020
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Ingår i: Journal of Cleaner Production. - : Elsevier. - 0959-6526 .- 1879-1786. ; 275
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Tidskriftsartikel (refereegranskat)abstract
- This study presents a comparison of the life cycle carbon emission (LCCO2) and embodied energy calculation between two kinds of bricks, sun-dried and fired clay, as means of evaluating the energy and climate impact of each brick type and the economics of production. Focus is paid to the differences across the whole production chain between sun-dried clay bricks, which represent the traditional norm, and fired clay bricks, which are the most widely-used walling materials in conventional buildings. A case study was carried out in Dakhla Oasis in the Western Desert of Egypt. The results of this study show that if sun-dried bricks are used instead of fired bricks, a reduction of up to 5907 kg CO(2)e (in CO2 emissions) and 5305 MJ of embodied energy for every1000 bricks produced could be achieved. The paper concludes by offering alternative scenarios for brick-making and suggestions for improving sun-dried brick production. The methodology used in this study contributes to the development of an investigative-comparative way to assess choices between building materials. It also intends to help inform local homeowners and building practitioners not only in Egypt, but also globally, about resource depletion, energy consumption, and harmful emissions from fired industrial bricks as a common building construction material. (C) 2020 The Authors. Published by Elsevier Ltd.
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| 3. |
- Dabaieh, Marwa, et al.
(författare)
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A life cycle assessment of a 'minus carbon' refugee house : global warming potential and sensitivity analysis
- 2020
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Ingår i: Archnet-IJAR. - : Emerald Group Publishing Limited. - 1994-6961 .- 1938-7806. ; 14:3, s. 559-579
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Tidskriftsartikel (refereegranskat)abstract
- Purpose - Over the last eight years, the Middle East has experienced a series of high profile conflicts which have resulted in over 5.6 million Syrians forced to migrate to neighbouring countries within the MENA (Middle East and North Africa) region or to Europe. That have exerted huge pressure on hosting countries trying to accommodate refugees in decent shelters and in quick manner. Temporary shelters normally carry a high environmental burden due to their short lifespan, and the majority are fabricated from industrialised materials. This study assesses the carbon impact for a minus carbon experimental refugee house in Sweden using life cycle assessment (LCA) as tool. SimaPro and GaBi software were used for the calculations and the ReCiPe midpoint method for impact assessment. The results show that using local plant-based materials such as straw, reeds and wood, together with clay dug from close to the construction site, can drastically reduce the carbon footprint of temporary shelters and even attain a negative carbon impact of 226.2 kg CO2 eq/m2. Based on the results of the uncertainty importance analysis, the overall global warming potential impact without and with sequestration potential are mostly sensitive to the variability of the GWP impact of wood fibre insulation. Design/methodology/approach - The methodology is designed to calculate the GWP impact of the refugee house over its entire life cycle (production, operation and maintenance and end of life). Then, the sensitivity analysis was performed to explore the impact of input uncertainties (selection of material from the database and the method) on the total GWP impact of the refugee house with and without sequestration. The ISO standards (International Standard 14040 2006; International Standard 14044 2006) divide the LCA framework into four steps of Goal and scope, inventory analysis, impact assessment, and interpretation. Findings - This study has shown an example for proof of concept for a low impact refugee house prototype using straw, reeds, clay, lime and wood as the principle raw materials for building construction. Using natural materials, especially plant-based fibres, as the main construction materials, proved to achieve a minus carbon outcome over the life cycle of the building. The GWP of the shelter house without and with sequestration are found to be 254.7 kg CO2 eq/m(2) and -226.2 kg CO2 eq/m(2), respectively. Originality/value - As there are still very few studies concerned with the environmental impact of temporary refugee housing, this study contributes to the pool of knowledge by introducing a complete LCA calculation for a physical house prototype as a proof of concept on how using low impact raw materials for construction combined with passive solutions for heating and cooling can reach a minus carbon outcome. The GWP of the shelter house without and with sequestration are found to be 254.7 kg CO2 eq/m2 and -226.2 kg CO2 eq/m2.
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| 4. |
- Heinonen, Jukka, et al.
(författare)
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An Empirical Inquiry on the Effect of Cleaner Local Energy Production on Consumer Carbon Footprint
- 2012
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Ingår i: Design for Innovative Value Towards a Sustainable Society. - Dordrecht : Springer Netherlands. - 9789400730106 ; , s. 160-164
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Bokkapitel (refereegranskat)abstract
- This study analyzes the effect of cleaner local energy production on the consumer carbon footprint. The results in consumption based carbon footprint assessments have traditionally indicated that a significant change in consumption patterns or lifestyles would be needed to achieve the often aspired, ambitious 50- 80% cutoffs in the carbon emissions on a community level. However, it is also known that a majority of the emissions related to all goods and services derives from energy. Thus cleaner local energy would not affect only the emissions from housing in the consumer carbon footprint but also the carbon load from the consumption of goods and services produced with the same energy.
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| 5. |
- Heinonen, Jukka, et al.
(författare)
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City level carbon mitigation strategies : What are their true impacts?
- 2012
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Ingår i: International Journal of Sustainable Building Technology and Urban Development. - 2093-761X. ; 3:1, s. 54-59
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Tidskriftsartikel (refereegranskat)abstract
- This paper addresses the problems associated with ambitious greenhouse gas (GHG) emission cut-off targets set for cities in recent years. Even though many cities have adopted an active approach to sustainability issues and climate change mitigation, they often lack appropriate and effective tools for achieving the cut-off targets. The primary purpose of this paper is to demonstrate the utilisation of a consumption based GHG emission assessment model in city level carbon management. The demonstration is executed by an evaluation of four different scenarios for city level carbon mitigation, including the construction of low-emission buildings, increasing the use of renewable energy sources, restricting urban sprawl and reducing private driving together with an increase in the share of public transportation. The study shows that a life cycle assessment (LCA) model like the one utilised here can be operated effectively in city level carbon management. Furthermore, the comprehensive, consumption based assessment model, even though used locally, provides a global view on a global issue. The results of the assessment suggest that the only way to significantly reduce the carbon emissions, within a short time period, on a city level is to change the carbon intensity of the local energy production. Other mitigation strategies might be of importance too, but the limitations and dimensions of the impacts should be understood.
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| 6. |
- Heinonen, Jukka, et al.
(författare)
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Dense downtown living more carbon intense due to higher consumption : A case study of Helsinki
- 2011
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Ingår i: Environmental Research Letters. - : IOP Publishing. - 1748-9326. ; 6:3
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Tidskriftsartikel (refereegranskat)abstract
- Hindering urban sprawl is one of the main goals for contemporary urban planning. Urban density is considered crucial in climate change mitigation since it reduces automobile dependence and decreases unit sizes, for example. This letter analyzes the effect of density in a city context. In the study the Finnish capital Helsinki is divided into two areas of different urban densities: the high density downtown area and the more scarcely populated suburbs. The study is a continuation of a recently published study on the implications of urban structure on carbon emissions, and analyzes further the main finding of the first study - that higher urban density might have negligible or even reverse effect on the per capita carbon emissions. Similarly to the previous study, a consumption based tiered hybrid life cycle assessment (LCA) approach is employed in order to produce a comprehensive assessment, free of territorial boundaries and system cutoffs typical of traditional LCAs. Based on the findings of the previous study, it is hypothesized that when assessing city level carbon dioxide emissions from a wider, consumer oriented LCA perspective, increased urban density may not necessarily reduce carbon emissions. Surprisingly, the study finds that carbon dioxide equivalent (CO2e) emissions are substantially higher in the dense downtown area than in the surrounding suburbs, which is suggested to imply that the increased consumption due to the higher standard of living increases emissions more than the higher density is able to reduce them. The results demonstrate that, while increasing urban density can be justified from a number of ecological, social and economic viewpoints, density is not necessarily a key parameter in the particular case of climate change. In cities like Helsinki, where wealth is concentrated in the downtown area, climate policies should give higher priority to the energy consumption of buildings, to alternative energy production and distribution modes, as well as to low carbon consumption within the city.
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| 7. |
- Jack, Tullia, et al.
(författare)
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How individuals make sense of their climate impacts in the capitalocene : mixed methods insights from calculating carbon footprints
- 2023
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Ingår i: Sustainability Science. - 1862-4065.
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Tidskriftsartikel (refereegranskat)abstract
- Many people want to play their part to tackle climate change, but often do not know where to start. Carbon Footprint (CF) Calculators pose potential for helping individuals situate themselves in climate impacting systems of which they are a part. However, little is currently known about whether and how individuals who complete CF calculators understand their CF in the context of climate change. This article explores how people make sense of their CFs and locate themselves in the capitalocene. It draws on theories of social practices, environmental ethics, valuation, and knowledge-use to analyse data from 500+ Danes who completed a CF calculator (https://carbonfootprint.hi.is) and interviews with 30 Danes who were asked to complete the CF calculator. In this article, we describe how Danes’ CFs are impacted, looking at how survey respondents rate importance of mitigating climate change, importance of personal actions, and importance of public steering, as well as disposable income, living space, and family type. We also show how interviewees reflect over their consumption activities and possibilities. Those with high income nearly always had high CF but felt like they had little agency to change the system and rather justified their high-emitting practices such as flying, while those with low CF felt they had more agency in the system. The results show that high-CF individuals resist voluntary reduction of their emissions despite the presence of environmental ethics. Thus, we conclude that systemic solutions have the foremost capacity to reduce carbon emissions.
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| 8. |
- Kai, Lehtimaki, et al.
(författare)
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Successful management of super-refractory status epilepticus with thalamic deep brain stimulation
- 2017
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Ingår i: Annals of Neurology. - : WILEY-BLACKWELL. - 0364-5134 .- 1531-8249. ; 81:1, s. 142-146
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Tidskriftsartikel (refereegranskat)abstract
- Super-refractory status epilepticus is a condition characterized by recurrence of status epilepticus despite use of deep general anesthesia, and it has high morbidity and mortality rates. We report a case of a 17-year-old boy with a prolonged super-refractory status epilepticus that eventually resolved after commencing deep brain stimulation of the centromedian nucleus of the thalamus. Later attempt to reduce stimulation parameters resulted in immediate relapse of status epilepticus, suggesting a pivotal role of deep brain stimulation in the treatment response. Deep brain stimulation may be a treatment option in super-refractory status epilepticus when other treatment options have failed. ANN NEUROL 2017;81:142-146
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| 9. |
- Kudomi, Nobuyuki, et al.
(författare)
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Myocardial Blood Flow and Metabolic Rate of Oxygen Measurement in the Right and Left Ventricles at Rest and During Exercise Using 15O-Labeled Compounds and PET
- 2019
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Ingår i: Frontiers in Physiology. - Lausanne : Frontiers Media S.A.. - 1664-042X. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- Aims: Simultaneous measurement of right (RV) and left ventricle (LV) myocardial blood flow (MBF), oxygen extraction fraction (OEF), and oxygen consumption (MVO2) non-invasively in humans would provide new possibilities to understand cardiac physiology and different patho-physiological states. Methods: We developed and tested an optimized novel method to measure MBF, OEF, and MVO2 simultaneously both in the RV and LV free wall (FW) using positron emission tomography in healthy young men at rest and during supine bicycle exercise. Results: Resting MBF was not significantly different between the three myocardial regions. Exercise increased MBF in the LVFW and septum, but MBF was lower in the RV compared to septum and LVFW during exercise. Resting OEF was similar between the three different myocardial regions (similar to 70%) and increased in response to exercise similarly in all regions. MVO2 increased approximately two to three times from rest to exercise in all myocardial regions, but was significantly lower in the RV during exercise as compared to septum LVFW. Conclusion: MBF, OEF, and MVO2 can be assessed simultaneously in the RV and LV myocardia at rest and during exercise. Although there are no major differences in the MBF and OEF between LV and RV myocardial regions in the resting myocardium, MVO2 per gram of myocardium appears to be lower the RV in the exercising healthy human heart due to lower mean blood flow. The presented method may provide valuable insights for the assessment of MBF, OEF and MVO2 in hearts in different pathophysiological states.
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| 10. |
- Kyrö, Riikka, et al.
(författare)
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Occupants have little influence on the overall energy consumption in district heated apartment buildings
- 2011
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Ingår i: Energy and Buildings. - : Elsevier BV. - 0378-7788. ; 43:12, s. 3484-3490
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this research is twofold: first, to evaluate how occupant behavior in a neutral environment influences the overall greenhouse gas emissions and energy consumption of multi-family apartment buildings, and second: to establish which activities associated with housing companies produce the most greenhouse gas emissions. The research comprised of a multiple cases of housing companies dating from the late 1960s and located in the Finnish capital Helsinki. The studied housing companies represent the least energy efficient third of the Finnish residential building stock, approaching obligatory large scale refurbishments. The analysis is conducted in two phases with a so called hybrid life-cycle assessment (LCA) technique. Using the technique, both economic and metric consumption data are analyzed to estimate the greenhouse gas emissions generated by activities associated with housing. In line with previous research, the study identifies heating energy as the single most significant contributor to greenhouse gas emissions. The results also show that the carbon load associated with housing activities makes up one third of an individual resident's overall carbon footprint. Contrary to often stated belief, the study indicates that occupant behavior has only limited effect on the energy consumption and, consequently, carbon emissions derived from housing, particularly when multi-family housing connected to district heating is concerned. However, apartment size seems to have a two-way impact, the smallest and the largest being the least energy efficient.
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