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| 2. |
- Danielsson, Marie, et al.
(författare)
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Mini-seedlings of Picea abies are less attacked by Hylobius abietis than conventional ones : Is plant chemistry the explanation?
- 2008
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Ingår i: Scandinavian Journal of Forest Research. - : Informa UK Limited. - 0282-7581 .- 1651-1891. ; 23:4, s. 299-306
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Tidskriftsartikel (refereegranskat)abstract
- The pine weevil, Hylobius abietis (L.), is a major pest in conifer reforestation areas in the Palaearctic region. Size and chemistry of the seedlings may explain the damage rates in plantations. The performance of 10-week containerized seedlings (mini-seedlings) was compared with 1-year-old conventional seedlings of Norway spruce, Picea abies (L.), in a field experiment in central Sweden. After 2 years the weevil damage was lower for the mini-seedlings than for the conventional seedlings (3.5 vs 55%). After 3 years, the overall survival was 82 and 75%, respectively. Weevil damage was the main cause of mortality for conventional seedlings, whereas mini-seedlings mainly died from drought. Volatiles of the two seedling types were compared by solid-phase microextraction-gas chromatography -mass spectrometry (SPME-GC-MS). Unwounded mini-seedlings and conventional seedlings differed in their compositions of monoterpenes and sesquiterpenes. Miniseedlings mainly emitted limonene, known to be repellent to the pine weevil. When wounded, green leaf volatiles were released by mini-seedlings while the pine weevil attractant alpha-pinene was released by conventional seedlings. Volatiles may partly explain the mini-seedlings' resistance against weevil attack. Further studies are needed to clarify how long this miniseedling effect remains.
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| 3. |
- Eriksson, Jemt Anna, et al.
(författare)
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Gamla Uppsalas landskapshistoria
- 1996
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Ingår i: Arkeologi och miljögeologi i Gamla Uppsala / redaktör: Wladyslaw Duczko. Vol. 2. - : Department of Archaeology, Uppsala University. ; 11, s. 157-178-
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Georgoudaki, Anna-Maria, et al.
(författare)
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Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis
- 2016
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Ingår i: Cell Reports. - : Elsevier BV. - 2211-1247. ; 15:9, s. 2000-2011
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Tidskriftsartikel (refereegranskat)abstract
- Tumors are composed of multiple cell types besides the tumor cells themselves, including innate immune cells such as macrophages. Tumor-associated macrophages (TAMs) are a heterogeneous population of myeloid cells present in the tumor microenvironment (TME). Here, they contribute to immunosuppression, enabling the establishment and persistence of solid tumors as well as metastatic dissemination. We have found that the pattern recognition scavenger receptor MARCO defines a subtype of suppressive TAMs and is linked to clinical outcome. An anti-MARCO monoclonal antibody was developed, which induces anti-tumor activity in breast and colon carcinoma, as well as in melanoma models through reprogramming-TAM-populations to a pro-inflammatory phenotype and increasing tumor immunogenicity. This anti-tumor activity is dependent on the inhibitory Fc-receptor, Fc gamma RIIB, and also enhances the efficacy of checkpoint therapy. These results demonstrate that immunotherapies using antibodies designed to modify myeloid cells of the TME represent a promising mode of cancer treatment.
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| 7. |
- Hellqvist, Magnus, 1964-, et al.
(författare)
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Analys av fynd av mollusker från Trekanten
- 2006
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Ingår i: Trekanten och Björkgården. - Uppsala : Societas Archaeologica Upsaliensis. - 9197599425 ; , s. 219-22
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Vid utgrävningen av boplatsen Trekanten (RAÄ 602), Gamla Uppsala sn i Uppland, har subfossila fynd av land och sötvattenssnäckor samt marina musslor analyserats. Fynden gjordes i jordprover från flera anläggningar som framkom vid utgrävningen. I de flesta provtagna anläggningarna med subfossila fynd av snäckor och musslor (mollusker) har det återfunnits en art i varje anläggning och bara i undantagsfall flera arter. Däremot uppvisar några av anläggningarna ett stort antal individer av samma art. Att tolka ett miljöhistoriskt material baserat på i princip en art i varje anläggning innebär alltid vissa risker, eftersom flera arter stärker tolkningen av ett fyndsammanhang.
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| 8. |
- Hellqvist, Magnus, 1964-, et al.
(författare)
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Insekter från Kyrsta : Analys av makrofossila insektlämningar i anläggningar från Kyrsta.
- 2006
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Ingår i: Kyrsta: Förhistoriska boplatslämningar. - Uppsala : Societas Archaeologica Upsaliensis. - 9197599492 - 9789197599498
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Vid utgrävningen av boplatsen Kyrsta (RAÄ 327), Ärentuna sn, Uppland, togs jordprover för insektsanalys från ett antal anläggningar (tabell 1) tolkade som brunnar. Syftet med denna undersökning var att se hur anläggningen hade utnyttjats, att tolka boplatsens närmiljö och att eventuellt se indikationer på det omgivande landskapets miljö.
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| 9. |
- Hellqvist, Magnus, 1964-, et al.
(författare)
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Land-use history in Gamla Uppsala, southeast Sweden, established on subfossil Coleoptera remains and pollen in fluvial deposits
- 2001
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Ingår i: Grana. - : Taylor & Francis. - 0017-3134 .- 1651-2049. ; 40:3, s. 142-153
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Tidskriftsartikel (refereegranskat)abstract
- Insect and pollen remains in fluvial sediments from the stream bank of river Fyris and one tributary brook, Samnan, in south-eastern Sweden, were studied. The deposits cover the last 400 years, according to 1 4C dates. The insects, dominated by subfossil beetles, originate foremost from stream environments, indicating aquatic development. Scarce finds from a wider area are recorded, particularly in samples from the banks of Fyris river there is a strong influence from surrounding land. Pollen originates from the surrounding cultivated field and grazing areas as well as wet meadows. The dominance of the stream environment changes along the examined core. The land-use history as it is reflected by deposited subfossils are compared with old maps from the area. It is demonstrated that the source areas for subfossil beetle and pollen have changed over time. Consequently, it is difficult to estimate the area for which the land-use history is accurate. For test purposes, the Mutual Climatic Range (MCR) method has been used for reconstructing mean temperatures based on the beetle record.
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