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- Hellström, Anders, et al.
(författare)
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Nostalgia and Hope : Narrative Master Frames Across Contemporary Europe
- 2020
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Ingår i: Nostalgia and Hope: Intersections between Politics of Culture, Welfare, and Migration in Europe. - Cham : Springer International Publishing. - 2364-4087 .- 2364-4095. - 9783030416942 - 9783030416935 ; , s. 1-16
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Bokkapitel (refereegranskat)abstract
- After the fall of the Berlin wall and the end of the Cold War, a certain sense of optimism swept across Europe. Some 25 years later, everything seems radically different. With the considerable inroads made into mainstream politics by right-wing populist parties across the continent, there is no shortage of gloom and worry. Nevertheless, despite numerous examples of retrogressive forms of mobilization, there are also many cases of progressive mobilization. To capture this dynamic complexity, we posit politics as a site of struggle that constitutes an arena for the conflicting demands of the two master frames of nostalgia and hope. Following this logic of a polarized political terrain, the volume is divided into three parts that address both right-wing populist politics across Europe (Part I) and politics beyond party politics through either retrogressive mobilization (Part II) or emancipatory initiatives (Part III).
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| 5. |
- Hellström, Martin, et al.
(författare)
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Schuld und Scham : Psychologische Hemmung oder weltbewegende Kraft?
- 2014
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Ingår i: Leitkulturen und Wertediskussionen. Zur Darstellung von Zeitgeschichte in deutschsprachiger Gegenwartsliteratur. - : iudicium. - 9783862054527 ; , s. 39-57
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Den antologi som artikeln publiceras i bearbetar frågan om värderinger och led-kulturer (Leitkulturen) i Europa. Artikeln undersöker mot bakgrund av olika litterära verk hur begreppen 'skam' och 'skuld' bearbetas och under de senaste 200 åren har förändrats vad gäller valör och betydelse. Det visar sig att de har stor betydelse för en individs identitetskonstruktion, men att de förlorar sin betydelse pga en förandrad syn på just identiteten. I en värld där det finns en totalitet av sambanden och där allt befinner sig i ett allomfattande nätverk är individens gränser allt mer flytande, vilket korresponderar med att bl.a. moraliska begrepp tappar sin betydelse och kraft. Dagens värdedebatt är således inte bara konservativ vad gäller enskilda (moraliska) värderingar utan framför allt pga av att dessa värderingar kopplas till en föråldarad syn på individen där den inte uppfattas som splittrad och indragen i óändliga nätverk utan som avgränasad och överblickbar.
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| 6. |
- Hadrévi, Jenny, et al.
(författare)
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Systemic differences in serum metabolome : a cross sectional comparison of women with localised and widespread pain and controls
- 2015
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Chronic musculoskeletal pain exists either as localised to a single region or as widespread to multiple sites in several quadrants of the body. Prospective studies indicate that widespread pain could act as a far end of a continuum of musculoskeletal pain that started with chronic localised pain. The mechanism by which the transition from localised pain to widespread occurs is not clear, although many studies suggest it to be an altered metabolism. In this study, systemic metabolic differences between women with chronic localised neck-shoulder pain (NP), women with chronic widespread pain (CWP) and women who were healthy (CON) were assessed. Blood samples were analysed taking a metabolomics approach using gas chromatography mass spectrometry (GC-MS) and orthogonal partial least square discriminant analysis (OPLS-DA). The metabolomics analysis showed a clear systematic difference in the metabolic profiles between the subjects with NP and the CON but only a weak systematic difference between the subjects with CWP and the CON. This most likely reflects a difference in the portion of the metabolome influenced by the two pain conditions. In the NP group, the overall metabolic profile suggests that processes related to energy utilisation and lipid metabolism could be central aspects of mechanisms maintaining disorder.
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| 8. |
- Hellström, Martin, et al.
(författare)
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Expression of the CD44 receptor in the blood vessel system : an experimental study in rat.
- 2005
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Ingår i: Cells Tissues Organs. - : S. Karger AG. - 1422-6405 .- 1422-6421. ; 179:3, s. 102-108
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Tidskriftsartikel (refereegranskat)abstract
- The CD44 receptor is a transmembrane glycoprotein expressed on a variety of cells like endothelial, epithelial and smooth muscle cells. This molecule has many important functions, e.g. in cell-cell and cell-matrix interactions and signal transduction. The main ligand for CD44 is hyaluronan (HYA). HYA is a glycosaminoglycan with structural and cell biological properties. The localization of HYA in the vessel wall of arteries and veins in the healthy adult and newborn rat has been described earlier. In this study the occurrence of the CD44 receptor was investigated in the same vessels and compared to the localization of HYA. Both CD44 and its ligand showed an increased expression in the vessel wall of newborn rats compared to that of adult rats. Although HYA is abundant in the adventitia of adult rats, virtually no expression of CD44 was observed. Our results indicate that the CD44 receptor expression is increased during the stage of maturation of the vessel tree whereas the CD44 receptor is less needed by HYA in the healthy vessel wall.
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| 9. |
- Hellström, Martin, et al.
(författare)
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Hyaluronan is differently located in arteries and veins : an immunohistochemical study in the rat
- 2003
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Ingår i: Cells Tissues Organs. - : S. Karger AG. - 1422-6405 .- 1422-6421. ; 173:4, s. 227-233
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Tidskriftsartikel (refereegranskat)abstract
- The matrix components of the vessel wall are of great importance for the function of the vessel system of which both endurance and elasticity are prerequisites. One component of the vessel wall is the glycosaminoglycan hyaluronan (HYA) with its unique physico-chemical properties, e.g. viscoelasticity and barrier function. The present study aimed to map and compare the normal localisation and distribution of hyaluronan in the arteries and veins of both adult and newborn rats, using a specific staining method utilizing a hyaluronan-binding protein. The hyaluronan stained clearly different in veins and arteries both in newborn and adult rats. In the veins, the tunica intima stained intensely whereas the corresponding area in the arteries only showed a weak and scattered staining pattern. In the adult rats, the matrix between the smooth muscle cells of the tunica media of the veins had a clearly positive staining pattern compared to the media in the arteries which showed only a few scattered areas of positive staining. In the newborn rats, the media of the arteries stained more intensely. In both newborn and adult rats, the adventitia stained intensely both in veins and arteries. Moreover, the HYA-staining pattern differed in veins in different regions of the body. Since HYA is known to be involved in many different biological processes, the results are of importance to understand physiological properties of the vessel tree and to explain the development of vascular diseases.
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| 10. |
- Hellström, Martin, et al.
(författare)
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The structure of the basement membrane zone differs between keloids, hypertrophic scars and normal skin : A possible background to an impaired function
- 2014
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Ingår i: Journal of Plastic, Reconstructive & Aesthetic Surgery. - : Elsevier BV. - 1748-6815 .- 1878-0539. ; 67:11, s. 1564-1572
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Tidskriftsartikel (refereegranskat)abstract
- Scar tissues were collected from patients with keloids, hypertrophic scars and mature scars. Normal skin was obtained from healthy individuals. Clinical attributes were used to select which tissue to obtain but the distribution of the specific hyaluronan (HA) staining was then used for the definite classification of the various scar types. Light microscopic and ultrastructural analyses were performed with an HA-binding probe, antibodies for collagen I and III and staining for mast cells. Ultrastructural studies of keloids revealed an altered collagen structure in the dermal layers, with an abundance of collagen fibres of similar diameter in both the reticular dermis (RD) and the papillary dermis (PD) compared to normal skin. Furthermore, the keloids displayed epidermal changes, which involved the basement membrane (BM), with fewer hemidesmosomes and an altered shape of desmosomes in the entire enlarged spinous layer. The frequency of mast cells found in keloids was lower than in other scar tissues and normal skin. These alterations in epidermis could influence the hydrodynamic and cell regulatory properties of the wounded skin with impaired function and insufficient regulative capacity to hinder the ever-growing collagen tissue that is characteristic for keloids. (C) 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
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