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Sökning: WFRF:(Helminen Hanna)

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2.
  • Koistinen, Arto P, et al. (författare)
  • Short-term exercise-induced improvements in bone properties are for the most part not maintained during aging in hamsters.
  • 2014
  • Ingår i: Experimental Gerontology. - : Elsevier BV. - 1873-6815 .- 0531-5565. ; 51, s. 46-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Physical exercise during growth affects composition, structure and mechanical properties of bone. In this study we investigated whether the beneficial effects of exercise during the early growth phase have long-lasting effects or not. Female Syrian golden hamsters (total n=152) were used in this study. Half of the hamsters had access to running wheels during their rapid growth phase (from 1 to 3months of age). The hamsters were sacrificed at the ages of 1, 3, 12, and 15months. The diaphysis of the mineralized humerus was analyzed with microCT and subjected to three-point-bending mechanical testing. The trabecular bone in the tibial metaphysis was also analyzed with microCT. The collagen matrix of the humerus bone was studied by tensile testing after decalcification. The weight of the hamsters as well as the length of the bone and the volumetric bone mineral density (BMDvol) of the humerus was higher in the running group at the early age (3months). Moreover, the mineralized bone showed improved mechanical properties in humerus and had greater trabecular thickness in the subchondral bone of tibia in the runners. However, by the age of 12 and 15months, these differences were equalized with the sedentary group. The tensile strength and Young's modulus of decalcified humerus were higher in the runners at early stage, indicating a stronger collagen network. In tibial metaphysis, trabecular thickness was significantly higher for the runners in the old age groups (12 and 15months). Our study demonstrates that physical exercise during growth improves either directly or indirectly through weight gain bone properties of the hamsters. However, the beneficial effects were for the most part not maintained during aging.
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3.
  • Norrbo, Isabella, et al. (författare)
  • Lanthanide and Heavy Metal Free Long White Persistent Luminescence from Ti Doped Li-Hackmanite : A Versatile, Low-Cost Material
  • 2017
  • Ingår i: Advanced Functional Materials. - : Wiley. - 1616-301X .- 1616-3028. ; 27:17
  • Tidskriftsartikel (refereegranskat)abstract
    • Persistent luminescence (PeL) materials are used in everyday glow-in-the-dark applications and they show high potential for, e.g., medical imaging, night-vision surveillance, and enhancement of solar cells. However, the best performing materials contain rare earths and/or other heavy metal and expensive elements such as Ga and Ge, increasing the production costs. Here, (Li,Na)(8)Al6Si6O24(Cl,S)(2):Ti, a heavy-metal-and rare-earth-free low-cost material is presented. It can give white PeL that stays 7 h above the 0.3 mcd m(-2) limit and is observable for more than 100 h with a spectrometer. This is a record-long duration for white PeL and visible PeL without rare earths. The material has great potential to be applied in white light emitting devices (LEDs) combined with self-sustained night vision using only a single phosphor. The material also exhibits PeL in aqueous suspensions and is capable of showing easily detectable photoluminescence even in nanomolar concentrations, indicating potential for use as a diagnostic marker. Because it is excitable with sunlight, this material is expected to additionally be well-suited for outdoor applications.
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4.
  • Glasbey, JC, et al. (författare)
  • 2021
  • swepub:Mat__t
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