| 1. |
- Regev, A, et al.
(författare)
-
The Human Cell Atlas
- 2017
-
Ingår i: eLife. - : ELIFE SCIENCES PUBLICATIONS LTD. - 2050-084X. ; 6
-
Tidskriftsartikel (refereegranskat)
|
|
| 2. |
|
|
| 3. |
- Hansson, B. A. M., et al.
(författare)
-
Characterisation of a liquid-xenon jet laser-plasma extreme-ultraviolet source
- 2004
-
Ingår i: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 75:6, s. 2122-2129
-
Tidskriftsartikel (refereegranskat)abstract
- A liquid-xenon-jet laser-plasma source for extreme-ultraviolet (EUV) and soft-x-ray generation has been characterized. Being a source candidate for EUV lithography (EUVL), we especially focus on parameters important for the integration of the source in EUVL systems. The deep-ultraviolet (DUV) out-of-band radiation (=120–400 nm) was quantified, to within a factor of two, using a flying-circus tool together with a transmission-grating spectrograph resulting in a total DUV conversion efficiency (CE) of ~0.33%/2sr. The size and the shape of the xenon plasma was investigated using an in-band-only EUV microscope, based on a spherical Mo/Si multilayer mirror and a charge-coupled device detector. Scalability of the source size from 20–270 µm full width at half maximum was shown. The maximum repetition-rate sustainable by the liquid-xenon-jet target was simulated by a double-pulse experiment indicating feasibility of >17 kHz operation. The xenon-ion energy distribution from the plasma was determined in a time-of-flight experiment with a Faraday-cup detector showing the presence of multi-kilo-electron-volt ions. Sputtering of silicon witness plates exposed to the plasma was observed, while a xenon background of >1 mbar was shown to eliminate the sputtering. It is concluded that the source has potential to meet the requirements of future EUVL systems.
|
|
| 4. |
- Hemberg, O., et al.
(författare)
-
Stability of droplet-target laser-plasma soft x-ray sources
- 2000
-
Ingår i: Journal of Applied Physics. - : AIP Publishing. - 0021-8979 .- 1089-7550. ; 88:9, s. 5421-5425
-
Tidskriftsartikel (refereegranskat)abstract
- The spatial stability of microscopic target droplets used for laser-plasma soft x-ray generation in vacuum is investigated. A long-term drift in drop position is characterized with an ultrafast laser-diode imaging system. The drift is experimentally and theoretically shown to be due to a temperature-induced increase in target-liquid viscosity as a result of evaporation. Finally, the drift is compensated for and stable, long-term unattended operation of the source is demonstrated with an automatic phase-delay drop-to-laser synchronizing system. This is important for future compact lithography and microscopy systems.
|
|
| 5. |
- Hertz, Hans M., et al.
(författare)
-
Electron-Impact Liquid-Metal-Jet Hard x-Ray Sources
- 2014
-
Ingår i: Comprehensive Biomedical Physics. - : Elsevier. - 9780444536327 ; , s. 91-109
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The power and brightness of electron-impact microfocus x-ray sources have long been limited by thermal damage in the target. This is a major constraint for a wide range of biomedical applications, from imaging to diffraction. Here, we describe the development of an x-ray microfocus source based on a new target concept, the liquid-metal jet (LMJ). The regenerative nature of this target allows for significantly higher e-beam power density than on conventional targets, resulting in this source showing promise for >. 100. × higher brightness than state-of-the-art sources. We first discuss the basic physics of the two important subsystems of the source, LMJ in vacuum and focused electron-beam systems, and then describe the properties of several versions of the source, from early prototypes to the first LMJ sources now reaching the market. Finally, we review some early applications of the source for biomedical imaging and diffraction.
|
|
| 6. |
- Hertz, Hans M., et al.
(författare)
-
Laboratory x-ray micro imaging : Sources, optics, systems and applications
- 2009
-
Ingår i: Journal of Physics, Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 186
-
Tidskriftsartikel (refereegranskat)abstract
- We summarize the recent progress in laboratory-scale soft and hard x-ray micro imaging in Stockholm. Our soft x-ray work is based on liquid-jet laser-plasma sources which are combined with diffractive and multilayer optics to form laboratory x-ray microscopes. In the hard x-ray regime the imaging is based on a liquid-metal-jet electron-impact source which provides the necessary coherence to allow phase-contrast imaging with high fidelity.
|
|
| 7. |
- Hertz, Hans M., et al.
(författare)
-
Liquid-jet laser-plasma X-ray sources for microscopy and lithography
- 2001
-
Ingår i: Journal de Physique IV. - : EDP Sciences. - 1155-4339 .- 1764-7177. ; 11:PR2, s. 389-396
-
Tidskriftsartikel (refereegranskat)abstract
- We review the development of compact laser-plasma soft x-ray sources based on microscopic liquid-drop or liquid-jet targets. It is shown that such sources provide practically debris-free, high-flux operation at water-window and EUV wavelengths. This regenerative and solid-density target system holds promise for the generation of high-average power using high-repetition-rate lasers. Application of the source to compact x-ray microscopy, multi layer-op tics characterization and EUV lithography is briefly discussed.
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
- Howick, Virginia M., et al.
(författare)
-
The Malaria Cell Atlas : Single parasite transcriptomes across the complete Plasmodium life cycle
- 2019
-
Ingår i: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 365:6455
-
Tidskriftsartikel (refereegranskat)abstract
- Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We profiled the single-cell transcriptomes of thousands of individual parasites, deriving the first high-resolution transcriptional atlas of the entire Plasmodium berghei life cycle. We then used our atlas to precisely define developmental stages of single cells from three different human malaria parasite species, including parasites isolated directly from infected individuals. The Malaria Cell Atlas provides both a comprehensive view of gene usage in a eukaryotic parasite and an open-access reference dataset for the study of malaria parasites.
|
|
