| 1. |
- Ahlqvist, Jan, 1952-
(författare)
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The temporomandibular joint : Tomopraphic and CT assesment of its bone demarcations with reference to adjacent organs
- 1998
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The wall of the temporal bone separating the temporomandibular joint (TMJ) from surroundings organs, can be very thin and also have development defects. Distortion effects in the radiographic reproduction of these bone walls can result in misinterpretations when exanimating suspected pathologic changes in the region. These areas need to be radiographic identified prior to taking any invasive measures. Incorrect assessment of bone thickness may lead to serious sequelae due to the risk of penetration injury during invasive investigation or treatment of the TMJ or ear. The purpose of this project was to gain more detailed knowledge about the anatomy and topography of the TMJ with special reference to its bone demarcations regarding adjacent organs and to evaluate the tomographic and computed tomographic (CT) depiction of these bone walls. To obtain a basic analysis of the tissue anatomy and tomographic and CT reproduction of the TMJ region, autopsy specimens were studied. After CT and conventional tomography, the specimens were sectioned in a microtom. Three- dimensional orientation systems allowed identification of section depth in the radiograms and in the histologic sections, allowing the radiograms in turn to be correlated with the true anatomy. The angle of inclination relative to the perpendicular to established imaging planes the bone walls studied was examined in three projections in order to identify regions where the bone demarcation showed an unfavorable inclination regarding the possibility of valid radiographic representation. The thickness of the bone wall between the TMJ and the middle cranial fossa, measured in the thinnest part, varied between 0.08 and 3.62 mm, averaging 1.14 mm. The bone wall between the TMJ and the middle ear showed less variation in thickness ranging from 0.00 to 1.80 mm. The thickness of the bone wall separating the TMJ from the external auditory canal varied between 1.50 mm (lateral part) and 1.21 mm (central part), with a range of between 0.21 and 4.10 mm. Development defects of this bone wall were found in 5.2 % of the examined joints. The validity in tomographic depiction of these walls was highly dependent on an optimal orientation of the bone wall in relation to the image plane. The variations in the anatomy and sagittal dimension of the external auditory canal led to variations in tomographic blurring, and suggested the need for examinations after patient repositioning in cases of suspected bone resorbing lesions so that image aberration due to unfavorable inclination of the bone wall relative to the image plane may be excluded. CT of these bone walls was valid (± 10 %) for walls thicker than approximately 1 mm, forming an angle of less than 35® with the perpendicular to the scan plane when the bone wall thickness was determined as the full-width-at-half-maximum (FWHM). For bone walls thinner than 1 mm, and for those thicker than 1 mm and at an angle exceeding 35®, partial volume averaging effects resulted in a progressively increasing magnification of bone dimensions. Observer estimations of bone thickness from images obtained using conventional bone window settings (c=400, W=2000) showed good agreement for bone walls thicker than 1 mm and with an angle of inclination relative to the perpendicular to the image plane of less than approximately 25®. For bone walls thinner than 1 mm and for thicker than 1 mm with an inclination exceeding approximately 25®, the estimations resulted in a progressively increasing overestimation amounting 200% for gracile bone walls with an inclination of 45® to 50®. Determination of width or absence of the central white zone in images obtained with the described parameters could help to reduce the risk of overestimation of bone thickness. A considerable part of the bone walls separating the TMJ from the middle cranial fossa and the external auditory canal/middle ear, respectively, have dimensions and inclinations to established imaging planes used at TMJ examinations that make the depiction of these walls highly susceptible to image distortion.
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| 2. |
- Carlsson, J, et al.
(författare)
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Tumour therapy with radionuclides: assessment of progress and problems
- 2003
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Ingår i: Radiotherapy and Oncology. - 1879-0887. ; 66:2, s. 107-111
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Forskningsöversikt (refereegranskat)abstract
- Radionuclide therapy is a promising modality for treatment of tumours of haematopoietic origin while the success for treatment of solid tumours so far has been limited. The authors consider radionuclide therapy mainly as a method to eradicate disseminated tumour cells and small metastases while bulky tumours and large metastases have to be treated surgically or by external radiation therapy. The promising therapeutic results for haematological tumours give hope that radionuclide therapy will have a breakthrough also for treatment of disseminated cells from solid tumours. New knowledge related to this is continuously emerging since new molecular target structures are being characterised and the knowledge on pharmacokinetics and cellular processing of different types of targeting agents increases. There is also improved understanding of the factors of importance for the choice of appropriate radionuclides with respect to their decay properties and the therapeutic applications. Furthermore, new methods to modify the uptake of radionuclides in tumour cells and normal tissues are emerging. However, we still need improvements regarding dosimetry and treatment planning as well as an increased knowledge about the tolerance doses for normal tissues and the radiobiological effects on tumour cells. This is especially important in targeted radionuclide therapy where the dose rates often are lower than 1 Gy/h. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
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| 3. |
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| 4. |
- Eriksson, Louise, 1973-, et al.
(författare)
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Invasive forest pathogens in Europe : Cross-country variationin public awareness but consistency in policy acceptability
- 2019
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Ingår i: Ambio. - : Springer Netherlands. - 0044-7447 .- 1654-7209. ; 48:1, s. 1-12
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Tidskriftsartikel (refereegranskat)abstract
- Political action can reduce introductions of diseases caused by invasive forest pathogens (IPs) and public support is important for effective prevention. The public’s awareness of IP problems and the acceptability of policies aiming to combat these pathogens were surveyed in nine European countries (N = 3469). Although awareness of specific diseases (e.g., ash dieback) varied, problem awareness and policy acceptability were similar across countries. The public was positive towards policies for informational measures and stricter standards for plant production, but less positive towards restricting public access to protected areas. Multilevel models, including individual and country level variables, revealed that media exposure was positively associated with awareness of IP problems, and strengthened the link between problem awareness and policy acceptability. Results suggest that learning about IPs through the media and recognizing the associated problems increase policy acceptability. Overall, the study elaborates on the anthropogenic dimension of diseases caused by IPs.
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| 5. |
- Hietala, Jan, 1962-
(författare)
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Beslutet om Slussen påverkar hela regionen
- 2012
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Ingår i: Dagens nyheter. - : AB Dagens nyheter. - 1101-2447. ; 2012-03-19
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- The present debate on the interchange Slussen from the 1930s in central Stockholm lacks of visions. The discussion has a site-specific dimension, but at the same time also a regional and national dimension, and both discussions need to be conducted simultaneously. What is needed is an analysis of the Stockholm region and the country’s infrastructural problems.
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| 6. |
- Hietala, Jan, 1962-
(författare)
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Eat Work Rest : The Exhibition
- 2011
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Annan publikation (populärvet., debatt m.m.)abstract
- Eat Work Rest is a project about an artist’s private and public spheres. The artist Prince Eugen of Sweden, Duke of Närke (1865-1947) is set in focus. The prince’s life, as all other artists’, was separated in a private and a public sphere, and perhaps even more evidently so in his case due to his birth. The difference between the private and the public cut through the prince’s work as an artist, his social life, his official tasks and even in what was served in his home the palatial villa Waldemarsudde on the sea just outside the city centre of Stockholm. The project Eat Work Rest, consisting of a book and an exhibition, originates from a few sentences 1st curator Göran Söderlund at Prince Eugen’s Waldemarsudde uttered early on the New Year of 2009. We were in his office in the villa. He told that they – the management of the palace – had harboured plans to re-make the Prince’s study on the ground floor for some time. He said it almost as if en passant. The book includes texts by Charlotte Birnbaum, Power Ekroth and Christina Wistman. To give some understanding of the context, it should be mentioned that the interiors of three private chambers in the palace are missing since 1947, and of several guest rooms. These were removed, all according to the provisions of the Prince’s will. The exhibition consists of an installation piece, an associative reconstruction of the vanished study on the first floor and the Prince’s bedchamber, emptied from their original contents soon after the Prince’s death 1947. The chambers are re-constructed as moving digital images based on C.G. Rosenberg’s pictures of 1947, and excerpts from the documentary ‘A Summer Day at Waldemarsudde’, shot by Lennart Bernadotte in 1943, in form of back-projections on silver screen walls, which makes it possible for a viewer to experience the imagery from the inside too. The projections are 3 x 4 m and the installation covers an area of some 500 m2. I recognise both these colleagues as contributors to the final result, in a inter-textual sense. Objects and furniture essential for the original rooms, are on lone from Stopalo AB Stockholm. These furniture are set in new unorthodox positions not unlike large assemblages. In the room Eat we meet a kitchen table, some dining room chairs from the 18th century, a couple of pheasants, an egg-box and an IKEA lamp from the 1970. In the room Work we find a desk from the 18th century, and early 19th century lamp and rake for a tennis court. In the room Rest we find a pair of riding boots, a gentleman’s hat-box, a chair, an electrified chandelier, and an finally a 18th century cast iron dolphin. The objects were presented on 18th century rugs.
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| 7. |
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| 8. |
- Hietala, Jan, 1962-
(författare)
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Strawberry Hill : The First Bourgeois Collection
- 2011. - 1
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Ingår i: Eat Work Rest. - : Exercishallen Norr. - 9789163388002 ; , s. 25-33
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Bokkapitel (populärvet., debatt m.m.)abstract
- The groundbreaking aspects of the collection of curiosities accumulated at the villa Strawberry Hill, built in 1748-77, have been suggested in the past. However, even if the innovative importance of the collection as such has been recognised, the inevitable conclusion has not been drawn: it is the first bourgeois collection of any significance.
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| 9. |
- Hietala, Jan, 1962-
(författare)
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The Origins of the Modern Villa
- 2004
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Ingår i: Site. - Sven Olof Wallenstein. - 1650-7894. ; :12, s. 8-10
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Modern was something Horace Walpole (1707-97) wanted to be. The essay investigates in which sense it is possible to identify a certain methodology used by Walpole in his oeuvre, as a writer on gardens, architecture, collections, art and in his practice as a gardener, architect-builder and collector. It investigates whereas Walpole’s main project the villa Strawberry Hill may be seen as modern in an untimely sense, with its gardens and collection. It compares Walpole with his predecessors, contemporaries and epigones. It relates Walpole to his contemporary discourse and when relevant, to ours. It describes a moment of modernity avant la letre.
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| 10. |
- Kalm, Marie, 1981, et al.
(författare)
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Neurochemical Evidence of Potential Neurotoxicity After Prophylactic Cranial Irradiation.
- 2014
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Ingår i: International journal of radiation oncology, biology, physics. - : Elsevier BV. - 1879-355X .- 0360-3016. ; 89:3, s. 607-614
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Tidskriftsartikel (refereegranskat)abstract
- Toexamine whether cerebrospinal fluid biomarkers for neuroaxonal damage, neuroglial activation, and amyloid β-related processes could characterize the neurochemical response to cranial radiation.
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