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- Al Shakirchi, M, et al.
(författare)
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The Effects of Aspergillus fumigatus Colonization on Lung Function in Patients with Cystic Fibrosis
- 2021
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Ingår i: Journal of fungi (Basel, Switzerland). - : MDPI AG. - 2309-608X. ; 7:11
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Tidskriftsartikel (refereegranskat)abstract
- Aspergillus fumigatus is commonly isolated from CF airways. However, the impact on CF lung progression is not completely understood. In this study, using a 16-year retrospective observational cohort study (2000–2015) that included 132 patients, we determined the annual lung function, measured as percent predicted forced expiratory volume in the first second (ppFEV1), decline before and after the first colonization with A. fumigatus. Further, in the same individual, the ratios of lung function when patients were colonized with A. fumigatus and when they were not were calculated. The impact of eradication, with antifungal treatment or spontaneously, was assessed. The annual ppFEV1 was significantly lower after the first colonization with A. fumigatus. Furthermore, within the same individual, colonization with A. fumigatus for two and three years in a row was associated with 4.3% and 7.9% lower ppFEV1, respectively, compared to when not colonized. Finally, patients who eradicated A. fumigatus the following two years after colonization exhibited 9.9% and 14.5% higher ppFEV1 compared to patients who continued to produce cultures with A. fumigatus for two and three years. Our study demonstrated that A. fumigatus colonization was associated with a negative impact on lung function in the long term and eradication, spontaneously or with treatment, was associated with a better pulmonary outcome.
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- Ausmees, A, et al.
(författare)
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Observation of excitation-energy-dependent Xe 4d(5/2,3/2)(-1) lifetime widths
- 1999
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Ingår i: JOURNAL OF PHYSICS B-ATOMIC MOLECULAR AND OPTICAL PHYSICS. - : IOP PUBLISHING LTD. ; 32:9
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- The creation and decay of photon-excited Xe 4d(5/2,3/2)(-1) core-hole states has been studied in the photon energy region 70-110 eV, where photon absorption is dominated by the strong shape resonance. Unprecedented experimental quality has enabled the stu
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- Björneholm, O., et al.
(författare)
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Doppler splitting of in-flight auger decay of dissociating oxygen molecules : The localization of delocalized core holes
- 2000
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Ingår i: Physical Review Letters. - : AMERICAN PHYSICAL SOC. - 0031-9007 .- 1079-7114. ; 84:13, s. 2826-2829
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Tidskriftsartikel (refereegranskat)abstract
- By exploiting the core-excitation-induced dissociation of O-2, we find that the Auger emission exhibits a Doppler-like energy shift. We show this to be a manifestation of localization of the core hole and propose that the problem of core-hole localization versus delocalization in core-hole spectroscopies may be resolved by considering the nature of the measurement.
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- Burmeister, F, et al.
(författare)
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Nonadiabatic effects in photoelectron spectra of HCl and DCl. I. Experiment
- 2002
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Ingår i: Physical Review A (Atomic, Molecular and Optical Physics). - 1050-2947. ; 65:1
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Tidskriftsartikel (refereegranskat)abstract
- The HCl inner-valence photoelectron band at 26 eV binding energy has been recorded at high resolution. Discrete peaks arising from at least two separate vibrational progressions are superimposed on the broad continuum. Fano profiles are visible in one of the progressions. This indicates interference between superimposed electronic states, where weak avoided crossing allows two adiabatic states to couple. In the isotopic DCl molecular spectrum, the discrete lines are less pronounced, due to slower dissociation and therefore less coupling between the continuum and the bound state.
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- de, Brito AN, et al.
(författare)
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Femtosecond dissociation dynamics of core-excited molecular water
- 1999
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Ingår i: CHEMICAL PHYSICS LETTERS. - : ELSEVIER SCIENCE BV. - 0009-2614. ; 309:5-6, s. 377-385
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The fragmentation of the water molecule upon resonant core excitation and subsequent Auger decay has been studied by electron-ion coincidence spectroscopy. A qualitative comparison between the fragmentation patterns for H2O and D2O reveals that the anti-b
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