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- Nilsson, B O, et al.
(författare)
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Monoclonal antibodies against human blastocysts.
- 1995
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Ingår i: Upsala Journal of Medical Sciences. - 0300-9734 .- 2000-1967. ; 100:3
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Tidskriftsartikel (refereegranskat)abstract
- A panel of monoclonal antibodies against the implanting mouse blastocyst was tested for cross-reactivity to human blastocysts. The monoclonal antibodies were produced by intrasplenic immunization with living mouse blastocysts or egg-cylinders. Among the 13 anti-mouse blastocyst antibodies checked, 6 ones detected antigen epitopes also in human blastocysts. If the mouse-human cross-reacting antibodies detect similar antigens in blastocysts of the two species, the results imply that anti-mouse blastocyst antibodies with specific properties could be used for studying human blastocysts. This procedure opens for a way to obtain monoclonal antibodies for analysing human blastocysts.
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