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Sökning: WFRF:(Holmlund U)

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  • Ballantyne, Kaye N., et al. (författare)
  • Toward Male Individualization with Rapidly Mutating Y-Chromosomal Short Tandem Repeats
  • 2014
  • Ingår i: Human Mutation. - : John Wiley & Sons. - 1059-7794 .- 1098-1004. ; 35:8, s. 1021-1032
  • Tidskriftsartikel (refereegranskat)abstract
    • Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs in 14,644 related and unrelated males from 111 worldwide populations. Strikingly, greater than99% of the 12,272 unrelated males were completely individualized. Haplotype diversity was extremely high (global: 0.9999985, regional: 0.99836-0.9999988). Haplotype sharing between populations was almost absent except for six (0.05%) of the 12,156 haplotypes. Haplotype sharing within populations was generally rare (0.8% nonunique haplotypes), significantly lower in urban (0.9%) than rural (2.1%) and highest in endogamous groups (14.3%). Analysis of molecular variance revealed 99.98% of variation within populations, 0.018% among populations within groups, and 0.002% among groups. Of the 2,372 newly and 156 previously typed male relative pairs, 29% were differentiated including 27% of the 2,378 father-son pairs. Relative to Yfiler, haplotype diversity was increased in 86% of the populations tested and overall male relative differentiation was raised by 23.5%. Our study demonstrates the value of RMY-STRs in identifying and separating unrelated and related males and provides a reference database.
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  • Budelmann, D., et al. (författare)
  • Antiferromagnetic and superconducting proximity effects in YBa2Cu3O7-delta/PrBa2Cu3O7-delta superlattices
  • 2003
  • Ingår i: Physical Review B Condensed Matter. - 0163-1829 .- 1095-3795. ; 67, s. 140507-
  • Tidskriftsartikel (refereegranskat)abstract
    • We investigate the interplay between the antiferromagnetic and superconducting order parameters in YBa2Cu3O7-delta/PrBa2Cu3O7-delta superlattices by inelastic light scattering. The ratio of superconducting to antiferromagnetic order is varied through different modulations 4/6, 4/9, and 4/12 of (Y/Pr)Ba2Cu3O7-delta layers. This allows us to identify the proximity effect of the superconducting order parameter into the antiferromagnetic barrier as signified, e.g., by the sharpening of the two-magnon excitation. This proximity effect as well as gap feature and phonon anomalies reveals the delicate interplay between superconducting and antiferromagnetic order parameters.
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  • Holmlund, L., et al. (författare)
  • Exploring reasons for sick leave due to common mental disorders from the perspective of employees and managers - what has gender got to do with it?
  • 2022
  • Ingår i: International Journal of Qualitative Studies on Health and Well-Being. - : Informa UK Limited. - 1748-2623 .- 1748-2631. ; 17:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose The purpose of this study was to explore the employee and the managerial experience of reasons for sick leave due to CMDs in relation to work and private life, through the lens of a transactional perspective of everyday life occupation and gender norms. Methods Semi-structured interviews were conducted with 17 employees on sick leave due to CMDs and 11 managers. By using transactional and gender perspectives in a reflexive thematic analysis, themes were generated in a constant comparative process. Findings Four themes were identified: a) struggling to keep up with work pressure and worker norms; b) struggling with insecurity in an unsupportive work environment; c) managing private responsibilities through flexible work schedules, and d) managing emotions alongside unfavourable working conditions. Conclusion Sick leave due to CMDs was understood as related to experiences of accumulated events situated in different social, cultural, and societal contexts of everyday life. Practices and policies should encourage an open dialogue about work and private life and health between employees and managers. To build healthy and sustainable work environments practices should also aim for increased awareness of social norms. A better understanding may facilitate the identification of situations in work and private life that are problematic for the employee.
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